18 completed, 8 terminated, 7 unknown, 3 recruiting. 12 Phase 2, 9 Not applicable, 9 Phase 4, 7 Phase 1, 5 Phase 3.
Follow Dexamethasone sodium phosphate: new trials by email Literature Review of Dexamethasone sodium phosphate trials Research Report on Dexamethasone sodium phosphate
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Intravenous Dexamethasone (0 vs 4 vs 8 mg) as an Adjunct to PENG Block for Postoperative Analgesia in Total Hip Arthroplasty: A Randomized Double-Blind Trial Dexamethasone 4mg, Placebo, Dexamethasone 8mg - Osteoarthritis, Hip, Hip Osteoarthritis | Not applicable | Recruiting | Poznan University of Medical Sciences | 198 | 2026-05-08 | 2026-07-01 |
| Modified Thoracolumbar Interfascial Plane Block vs Retrolaminar Block for Pain in Lumbar Spine Surgeries Morphine, Bupivacaine, Dexamethasone - Postoperative Pain After Spinal Surgery | Not applicable | Recruiting | Zagazig University | 42 | 2025-10-01 | 2026-10-20 |
| Effect of IV Dexamethasone on Post-op Urinary Retention After Spinal Anesthesia Dexamethasone (IV), Normal Saline (0.9% NaCl) - Post Operative Urinary Retention, Spinal Aneshtesia | Not applicable | Active not recruiting | Al-Quds University | 1084 | 2025-08-20 | 2026-07-14 |
| Open-Label Extension of EryDex Study IEDAT-04-2022 Dexamethasone sodium phosphate - Ataxia Telangiectasia | Phase 3 | Terminated | Quince Therapeutics S.p.A. | 101 | 2024-12-11 | 2026-05-05 |
| Evaluate the Neurological Effects of EryDex on Subjects With A-T Dexamethasone sodium phosphate, Placebo - Ataxia Telangiectasia | Phase 3 | Completed | Quince Therapeutics S.p.A. | 105 | 2024-06-24 | 2026-04-30 |
| Effect of Single-Dose Dexamethasone on Postoperative Pain After Cesarean Section Under Spinal Anesthesia Dexamethasone (IV), Normal Saline 0.9% Infusion Solution - Spinal Anesthesia, Cesarean Section Pain | Phase 4 | Completed | KRL Hospital, Islamabad | 80 | 2024-03-01 | 2026-07-21 |
| PANDORA: Paravertebral AdjuNctive DexamethasOne Palmitate Reducing Chronic Pain After Caridiac Surgery Dexamethasone Palmitate, Dexamethasone Sodium Phosphate - Chronic Postoperative Pain | Not applicable | Completed | Xijing Hospital | 562 | 2023-07-11 | 2026-10-14 |
| Venetoclax Basket Trial for High Risk Hematologic Malignancies Venetoclax, Azacitidine, Cytarabine - Myelodysplastic Syndromes, de Novo, Myelodysplastic Syndromes, Secondary | Phase 1 | Recruiting | Andrew E. Place, MD | 30 | 2023-03-29 | 2026-03-12 |
| Effect of Submucosal Cryotherapy on Postoperative Endodontic Pain Cryotherapy, Diclofenac sodium, Dexamethasone sodium phosphate - Post-endodontic Pain | Not applicable | Completed | Ain Shams University | 52 | 2023-03-20 | 2024-02-08 |
| Intravitreal and Intracameral DEX in NPDR Dexamethasone sodium phosphate - Non-Proliferative Diabetic Retinopathy | Phase 3 | Enrolling by invitation | Affiliated Hospital of Nantong University | 80 | 2022-01-31 | 2025-04-30 |
| Sterile Amniotic Fluid Filtrate Epidural Injection. Amniotic Fluid Allograft, Dexamethasone sodium phosphate - Lumbar Spinal Stenosis | Phase 1 / Phase 2 | Completed | University of Utah | 58 | 2021-06-16 | 2026-09-25 |
| Comparison of the Efficacy of Different Steroids in the Treatment of Abnormal Scars (Keloids, Hypertrophic Scars) Betamethasone acetate + Betamethasone sodium phosphate, Dexamethasone sodium phosphate, Methylprednisolone acetate - Keloid, Hypertrophic Scar | Not applicable | Unknown | Tel-Aviv Sourasky Medical Center | 40 | 2020-11-01 | 2020-10-20 |
| Effect of Preoperative Steroid in Total Knee Arthroplasty Dexamethasone Sodium Phosphate, Saline Solution - Arthropathy of Knee | Phase 3 | Unknown | Assiut University | 86 | 2020-01-01 | 2019-12-23 |
| Extended and Controlled Release Liposomal Formulated Dexamethasone for Chronic Knee OA Pain TLC599, DSP, Normal Saline - Osteoarthritis of the Knee | Phase 3 | Completed | Taiwan Liposome Company | 504 | 2019-11-26 | 2024-10-08 |
| Intravenous Dexamethasone to Prolong Caudal Block Analgesia in Children Undergoing Hip Surgery Dexamethasone, Normal Saline, Caudal Block Anesthesia - Pain, Postoperative, Developmental Dysplasia of the Hip | Phase 4 | Completed | National Institute of Neurology, Tunisia | 54 | 2019-09-01 | 2026-10-26 |
| IV Steroids Versus Steroids Included in Block for Orthopedic Lower Limb Surgery Placebos, Dexamethasone Sodium Phosphate - Lower Limb Injury | Early Phase 1 | Completed | University of Arizona | 50 | 2019-06-05 | 2021-07-21 |
| A Phase 2, Open Label, Pharmacokinetic (PK) Study of TLC599 in Subjects With Osteoarthritis of the Knee TLC599, DSP - Osteoarthritis of the Knee | Phase 2 | Completed | Taiwan Liposome Company | 102 | 2019-01-21 | 2024-10-23 |
| Comparative Evaluation of the Effect of Prophylactic Intraligamentary Injection of Dexamethasone and Piroxicam on Postoperative Pain in Teeth With Symptomatic Irreversible Pulpitis Dexamethasone sodium phosphate, Piroxicam Injectable Solution, Mepivacaine HCL - Postoperative Pain | Not applicable | Unknown | Cairo University | 42 | 2018-12-25 | 2018-11-23 |
| Iontophoresis With Dexamethasone and Physical Therapy to Treat Apophysitis of the Knee in Pediatrics Dexamethasone Sodium Phosphate, Iontophoresis, Physical Therapy - Apophysitis; Juvenile | Phase 2 | Terminated | Children's Health System, Inc. | 45 | 2018-11-05 | 2024-03-06 |
| Local Anaesthetic and Steroid in the Ureter Levobupivacaine, Dexamethasone Sodium Phosphate, Placebos - Pain, Postoperative, Ureter Stone | Not applicable | Unknown | The Adelaide and Meath Hospital, incorporating The National Children's Hospital | 150 | 2018-11-01 | 2018-01-17 |
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Pain, Postoperative (7) · Multiple Myeloma (5) · Leukemia (4) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (4) · Recurrence (3) · Ataxia Telangiectasia (2) · Breast Neoplasms (2) · Leukemia, Myeloid, Acute (2) · Lymphoma (2) · Macular Edema (2) · Myelodysplastic Syndromes (2) · Nausea (2) · Neoplasms, Plasma Cell (2) · Osteoarthritis, Knee (2) · Vomiting (2)
Barbara Ann Karmanos Cancer Institute (3) · Quince Therapeutics S.p.A. (3) · Ain Shams University (2) · Taiwan Liposome Company (2) · Tampere University Hospital (2) · Therapeutic Advances in Childhood Leukemia Consortium (2) · Affiliated Hospital of Nantong University (1) · Al-Quds University (1) · Andrew E. Place, MD (1) · Assiut University (1) · Cairo University (1) · Celgene Corporation (1) · Children's Health System, Inc. (1) · Eastern Cooperative Oncology Group (1) · KRL Hospital, Islamabad (1)
United States (20) · Canada (4) · Egypt (3) · Italy (3) · Poland (3) · Australia (2) · China (2) · Denmark (2) · Finland (2) · Germany (2) · Norway (2) · Spain (2) · Switzerland (2) · United Kingdom (2) · Ireland (1)
Dirk Thye, MD (2) · Jeffrey A. Zonder, MD (2) · Abeer J Dar Hasan, MD (1) · Andrew E Place, MD, PhD (1) · Carl Brown, PhD (1) · Chong Lei, MD&phD (1) · Dana Reesman, PT, DPT (1) · Deborah T. Blumenthal, MD (1) · Hans C Lee (1) · Hatem Bakr, asst. prof (1) · Heather Grossman, MD (1) · Josee Paradis, MD (1) · Kenneth Taylor, MD (1) · Khadeja Elhossieny, Assist Prof (1)
PMID 23233571, PMID 23243282, PMID 24421329, PMID 27267105, PMID 27826874, PMID 29416652, PMID 31969338, PMID 33742240, PMID 39819928, PMID 41915069, PMID 42600624
P30CA022453 (3), 2017 (2), P30CA068485 (1), P30CA072720 (1), UM1CA186688 (1)