9 completed, 3 terminated, 1 withdrawn. 8 Phase 2, 4 Phase 1, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 8 | Completed 4, Terminated 3, Withdrawn 1 |
| Phase 1 | 4 | Completed 4 |
| Phase 3 | 2 | Completed 2 |
Follow denufosol tetrasodium: new trials by email Literature Review of denufosol tetrasodium trials Research Report on denufosol tetrasodium
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study of Denufosol Tetrasodium Inhalation Solution in Patients With Cystic Fibrosis (CF) Lung Disease Denufosol Tetrasodium (INS37217) Inhalation Solution, Placebo - Cystic Fibrosis | Phase 3 | Completed | Merck Sharp & Dohme LLC | 466 | 2008-02-01 | 2015-11-02 |
| Study of Denufosol Inhalation Solution in Patients With Mild to Moderate Cystic Fibrosis Lung Disease denufosol tetrasodium (INS37217) Inhalation Solution - Cystic Fibrosis | Phase 2 | Terminated | Merck Sharp & Dohme LLC | 6 | 2007-08-01 | 2015-04-03 |
| Study of Denufosol Inhalation Solution in Patients With Mild Cystic Fibrosis Lung Disease denufosol tetrasodium (INS37217) Inhalation Solution, Placebo - 0.9% w/v sodium chloride solution - Cystic Fibrosis | Phase 3 | Completed | Merck Sharp & Dohme LLC | 352 | 2006-07-01 | 2015-11-04 |
| Study to Treat Uveitis Associated Macular Edema denufosol tetrasodium (INS37217) Intravitreal Injection - Cystoid Macular Edema, Uveitis | Phase 2 | Terminated | Merck Sharp & Dohme LLC | 15 | 2005-09-01 | 2016-11-29 |
| A Study in Pediatric Patients With Cystic Fibrosis Lung Disease denufosol tetrasodium (INS37217) - Cystic Fibrosis | Phase 2 | Completed | Merck Sharp & Dohme LLC | 13 | 2005-08-01 | 2013-05-22 |
| A Study of Denufosol Tetrasodium Intravitreal Injection in Subjects With Post Cataract Extraction Macular Edema denufosol tetrasodium (INS37217) Intravitreal Injection - Macular Edema, Cystoid | Phase 2 | Withdrawn | Merck Sharp & Dohme LLC | 2005-08-01 | 2013-05-21 | |
| Study of Denufosol Tetrasodium in Patients With Cystic Fibrosis Lung Disease denufosol tetrasodium (INS37217) - Cystic Fibrosis | Phase 2 | Completed | Merck Sharp & Dohme LLC | 72 | 2005-01-01 | 2015-10-20 |
| Study of Denufosol (INS37217) in Subjects With Rhegmatogenous Retinal Detachment denufosol tetrasodium (INS37217) Intravitreal Injection - Retinal Detachment | Phase 2 | Terminated | Merck Sharp & Dohme LLC | 23 | 2004-06-01 | 2015-04-10 |
| A Pharmacokinetic Evaluation Study in Healthy Volunteers denufosol tetrasodium (INS37217) - Healthy | Phase 1 | Completed | Merck Sharp & Dohme LLC | 12 | 2003-04-01 | 2015-10-16 |
| Study of INS37217 Inhalation Solution in Mild to Moderate Cystic Fibrosis Lung Disease denufosol tetrasodium (INS37217) - Cystic Fibrosis | Phase 2 | Completed | Merck Sharp & Dohme LLC | 90 | 2003-04-01 | 2015-01-29 |
| A Pharmacokinetic Evaluation Study in Healthy Volunteers denufosol tetrasodium (INS37217) - Healthy | Phase 1 | Completed | Merck Sharp & Dohme LLC | 4 | 2002-11-01 | 2015-10-12 |
| A Study in Adult and Pediatric Patients With Cystic Fibrosis denufosol tetrasodium (INS37217) Inhalation Solution - Cystic Fibrosis | Phase 1 / Phase 2 | Completed | Merck Sharp & Dohme LLC | 63 | 2001-06-01 | 2015-02-16 |
| A Study in Subjects With Retinal Detachment denufosol tetrasodium (INS37217) Intravitreal Injection - Retinal Detachment | Phase 1 | Completed | Merck Sharp & Dohme LLC | 14 | 2001-05-01 | 2015-10-09 |
Cystic Fibrosis (7) · Lung Diseases (2) · Macular Edema (2) · Retinal Detachment (2) · Retinal Perforations (1) · Uveitis (1)
United States (3) · Australia (1) · Canada (1) · New Zealand (1)
Amy Schaberg, BSN (9) · Felix Ratjen, MD, PhD (1) · Robin Deterding, MD (1)