10 completed, 8 active not recruiting, 6 recruiting, 3 not yet recruiting. 27 Phase 3, 6 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 27 | Completed 10, Active not recruiting 8, Recruiting 6, Not yet recruiting 3 |
| Phase 2 | 6 | Not yet recruiting 3, Active not recruiting 2, Completed 1 |
Follow deltacortene: new trials by email Literature Review of deltacortene trials Research Report on deltacortene
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Testing the Use of High Dose Testosterone Followed by Darolutamide Compared to the Usual Care for Patients With Metastatic Prostate Cancer Abiraterone Acetate, Biospecimen Collection, Bone Scan - Metastatic Castration-Resistant Prostate Adenocarcinoma, Stage IVB Prostate Cancer AJCC v8 | Phase 2 / Phase 3 | Not yet recruiting | ECOG-ACRIN Cancer Research Group | 432 | 2027-01-06 | 2026-10-01 |
| Testing the Addition of a New Anti-Cancer Drug, Glofitamab to Usual Chemotherapy for Burkitt and Double Hit Lymphoma Biospecimen Collection, Bone Marrow Biopsy, Carboplatin - Recurrent Burkitt Lymphoma, Recurrent High Grade B-Cell Lymphoma With MYC and BCL2 Rearrangements | Phase 2 / Phase 3 | Not yet recruiting | National Cancer Institute (NCI) | 271 | 2026-10-30 | 2026-08-19 |
| Testing the Addition of Daratumumab to Chemotherapy for Treating Patients With Newly-Diagnosed T-Cell Lymphoblastic Leukemia (T-ALL) and T-Cell Lymphoblastic Lymphoma (T-LL) Biopsy Procedure, Biospecimen Collection, Bone Marrow Aspiration - Stage II T Lymphoblastic Leukemia/Lymphoma, Stage III T Lymphoblastic Leukemia/Lymphoma | Phase 2 / Phase 3 | Not yet recruiting | Children's Oncology Group | 1708 | 2026-08-28 | 2026-07-30 |
| Adding Pirtobrutinib to the Usual Treatment for People With Newly Diagnosed Richter Transformation, The PIRAMID Trial Biospecimen Collection, Computed Tomography, Cyclophosphamide - Richter Syndrome, Transformed Chronic Lymphocytic Leukemia to Diffuse Large B-Cell Lymphoma | Phase 3 | Recruiting | SWOG Cancer Research Network | 102 | 2026-08-04 | 2026-10-13 |
| REVELUTION-2: Relugolix+Abiraterone Acetate (AA) Versus Leuprolide+AA Cardiac Trial Abiraterone Acetate, Bicalutamide, Biospecimen Collection - Recurrent Prostate Carcinoma, Stage III Prostate Cancer AJCC v8 | Phase 3 | Recruiting | Emory University | 72 | 2025-01-31 | 2026-02-24 |
| Testing Whether the Addition of Carboplatin Chemotherapy to Cabazitaxel Chemotherapy Will Improve Outcomes Compared to Cabazitaxel Alone in People With Castrate-Resistant Prostate Cancer That Has Spread Beyond the Prostate to Other Parts of the Body Biospecimen Collection, Bone Scan, Cabazitaxel - Castration-Resistant Prostate Carcinoma, Stage IVB Prostate Cancer AJCC v8 | Phase 3 | Recruiting | SWOG Cancer Research Network | 528 | 2024-11-27 | 2026-01-22 |
| A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab Biospecimen Collection, Bleomycin Sulfate, Brentuximab Vedotin - Lugano Classification Limited Stage Hodgkin Lymphoma AJCC v8 | Phase 3 | Recruiting | National Cancer Institute (NCI) | 1875 | 2023-05-11 | 2026-10-29 |
| Nivolumab in Combination With Chemo-Immunotherapy for the Treatment of Newly Diagnosed Primary Mediastinal B-Cell Lymphoma Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy - Primary Mediastinal Large B-Cell Lymphoma | Phase 3 | Active not recruiting | National Cancer Institute (NCI) | 244 | 2021-10-05 | 2026-10-01 |
| Testing CC-486 (Oral Azacitidine) Plus the Standard Drug Therapy in Patients 75 Years or Older With Newly Diagnosed Diffuse Large B Cell Lymphoma Biospecimen Collection, Computed Tomography, Cyclophosphamide - Ann Arbor Stage III Diffuse Large B-Cell Lymphoma, Ann Arbor Stage IIX (Bulky) Diffuse Large B-Cell Lymphoma | Phase 2 / Phase 3 | Active not recruiting | National Cancer Institute (NCI) | 422 | 2021-05-20 | 2026-10-27 |
| Testing the Use of Steroids and Tyrosine Kinase Inhibitors With Blinatumomab or Chemotherapy for Newly Diagnosed BCR-ABL-Positive Acute Lymphoblastic Leukemia in Adults Biospecimen Collection, Blinatumomab, Bone Marrow Aspiration and Biopsy - B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1 | Phase 3 | Active not recruiting | National Cancer Institute (NCI) | 348 | 2021-01-25 | 2026-10-26 |
| Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy Biospecimen Collection, Blinatumomab, Bone Marrow Aspiration - B Acute Lymphoblastic Leukemia, B Lymphoblastic Lymphoma | Phase 3 | Recruiting | Children's Oncology Group | 5951 | 2019-10-31 | 2026-08-25 |
| Testing the Addition of a New Anti-cancer Drug, Venetoclax, to Usual Chemotherapy for High Grade B-cell Lymphomas Biospecimen Collection, Bone Marrow Biopsy, Computed Tomography - Diffuse Large B-Cell Lymphoma, Diffuse Large B-Cell Lymphoma, Not Otherwise Specified | Phase 2 / Phase 3 | Active not recruiting | National Cancer Institute (NCI) | 363 | 2019-10-22 | 2026-10-26 |
| A Study to Investigate Blinatumomab in Combination With Chemotherapy in Patients With Newly Diagnosed B-Lymphoblastic Leukemia Asparaginase Erwinia chrysanthemi, Blinatumomab, Cyclophosphamide - B Acute Lymphoblastic Leukemia, B Lymphoblastic Lymphoma | Phase 3 | Active not recruiting | National Cancer Institute (NCI) | 6720 | 2019-07-03 | 2026-10-01 |
| Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer Abiraterone, Bicalutamide, Degarelix - Castration Levels of Testosterone, Metastatic Prostatic Adenocarcinoma | Phase 3 | Recruiting | SWOG Cancer Research Network | 1273 | 2018-09-24 | 2026-10-08 |
| Brentuximab Vedotin and Combination Chemotherapy in Treating Children and Young Adults With Stage IIB, Stage IIIB, IVA, or IVB Hodgkin Lymphoma Bleomycin Sulfate, Brentuximab Vedotin, Cyclophosphamide - Ann Arbor Stage IIB Hodgkin Lymphoma, Ann Arbor Stage IIIB Hodgkin Lymphoma | Phase 3 | Active not recruiting | National Cancer Institute (NCI) | 600 | 2015-03-19 | 2026-10-01 |
| Combination Chemotherapy With or Without Blinatumomab in Treating Patients With Newly Diagnosed BCR-ABL-Negative B Lineage Acute Lymphoblastic Leukemia Allogeneic Hematopoietic Stem Cell Transplantation, Biospecimen Collection, Blinatumomab - Acute Lymphoblastic Leukemia, B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative | Phase 3 | Active not recruiting | National Cancer Institute (NCI) | 488 | 2014-05-19 | 2026-09-21 |
| Combination Chemotherapy in Treating Young Patients With Newly Diagnosed High-Risk B Acute Lymphoblastic Leukemia and Ph-Like TKI Sensitive Mutations Clofarabine, Cyclophosphamide, Cytarabine - B Acute Lymphoblastic Leukemia, B Acute Lymphoblastic Leukemia, BCR-ABL1-Like | Phase 3 | Completed | National Cancer Institute (NCI) | 5949 | 2012-02-29 | 2026-06-02 |
| Calaspargase Pegol or Pegaspargase and Combination Chemotherapy in Treating Younger Patients With Newly Diagnosed High-Risk Acute Lymphoblastic Leukemia Calaspargase Pegol-mknl, Cyclophosphamide, Cytarabine - Acute Lymphoblastic Leukemia, Adult B Acute Lymphoblastic Leukemia | Phase 3 | Completed | Children's Oncology Group | 166 | 2008-07-21 | 2021-04-27 |
| Dasatinib and Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Acute Lymphoblastic Leukemia Asparaginase, Cyclophosphamide, Cytarabine - Acute Lymphoblastic Leukemia, Adult B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1 | Phase 2 / Phase 3 | Completed | National Cancer Institute (NCI) | 63 | 2008-07-14 | 2020-04-13 |
| Melphalan, Prednisone, and Thalidomide or Lenalidomide in Treating Patients With Newly Diagnosed Multiple Myeloma Laboratory Biomarker Analysis, Lenalidomide, Melphalan - Multiple Myeloma | Phase 3 | Active not recruiting | National Cancer Institute (NCI) | 306 | 2008-02-29 | 2026-10-01 |
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Burkitt Lymphoma (7) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (5) · Prostatic Neoplasms (4) · Hodgkin Disease (2) · Leukemia, Biphenotypic, Acute (2) · Lymphoma, Large B-Cell, Diffuse (2) · Precursor B-Cell Lymphoblastic Leukemia-Lymphoma (2) · Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (2) · Down Syndrome (1) · Glomerulonephritis, IGA (1) · Lymphoma (1) · Lymphoma, B-Cell, Marginal Zone (1) · Multiple Myeloma (1) · Neuroblastoma (1) · Proteinuria (1)
National Cancer Institute (NCI) (13) · Children's Oncology Group (7) · SWOG Cancer Research Network (3) · A. Manzoni Hospital (1) · ECOG-ACRIN Cancer Research Group (1) · Emory University (1) · Fondazione Michelangelo (1)
United States (22) · Canada (13) · Australia (10) · Puerto Rico (10) · New Zealand (8) · Switzerland (5) · Israel (4) · Chile (1) · Colombia (1) · Ireland (1) · Italy (1) · Mexico (1)
Alessandro M Gianni, MD (1) · Alexander K Stewart (1) · Anne L Angiolillo (1) · Brian Chapin (1) · Debra Friedman (1) · Elizabeth A Brem (1) · Eric C Larsen (1) · Jennifer L McNeer (1) · Jeremy S Abramson (1) · Joanne M Hilden (1) · Kara M Kelly (1) · Keith J August (1) · Kristie A Blum (1) · Lisa G Roth (1) · Mark R Litzow (1)
PMID 37505794, PMID 37890117, PMID 39121442, PMID 41671463, PMID 42085640, PMID 21774708, PMID 24970932, PMID 25311218, PMID 26124497, PMID 26157076, PMID 26265699, PMID 26590194, PMID 29284596, PMID 29296710, PMID 29376112, PMID 29812996, PMID 30138085, PMID 30626253, PMID 32414848, PMID 32496902, PMID 32552472, PMID 32589970, PMID 32813610, PMID 33242441, PMID 33496745, PMID 33512412, PMID 33844429, PMID 34302711, PMID 34634256, PMID 34662378, PMID 34686472, PMID 36322844, PMID 36603187, PMID 36868525, PMID 37556734, PMID 37947987, PMID 38446568, PMID 39047240, PMID 39058966, PMID 39058968, PMID 39651791, PMID 39969278, PMID 40135712, PMID 40533067, PMID 40700618, PMID 40990939, PMID 41592282, PMID 42660130, PMID 42832396
U10CA180886 (10), U10CA098543 (8), U10CA180820 (4), U10CA180888 (4), U10CA021115 (2), U10CA180821 (2), P30CA138292 (1), U10CA013539 (1), U24CA196172 (1)