3 completed, 1 recruiting. 4 Phase 1, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 4 | Completed 3, Recruiting 1 |
| Phase 2 | 4 | Completed 3, Recruiting 1 |
Follow Dantrolene: new trials by email Literature Review of Dantrolene trials Research Report on Dantrolene
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Targeting Residual Activity By Precision, Biomarker-Guided Combination Therapies of Multiple Sclerosis (TRAP-MS) Cilostazol, Leucovorin, Pirfenidone - Multiple Sclerosis | Phase 1 / Phase 2 | Recruiting | National Institute of Allergy and Infectious Diseases (NIAID) | 250 | 2017-08-11 | 2026-10-20 |
| A Clinical Trial of Dantrolene Sodium in Pediatric and Adult Patients With Wolfram Syndrome dantrolene sodium - Wolfram Syndrome, Diabetes Mellitus | Phase 1 / Phase 2 | Completed | Washington University School of Medicine | 21 | 2017-01-01 | 2024-03-13 |
| Safety Study of Dantrolene in Subarachnoid Hemorrhage Dantrolene, Placebo - Subarachnoid Hemorrhage, Cerebral Vasospasm | Phase 1 / Phase 2 | Completed | University of Massachusetts, Worcester | 31 | 2009-10-01 | 2015-03-05 |
| Safety Study of Dantrolene to Treat Cerebral Vasospasm After Subarachnoid Hemorrhage Dantrolene - Cerebral Vasospasm After Subarachnoid Hemorrhage | Phase 1 / Phase 2 | Completed | University of Massachusetts, Worcester | 10 | 2007-07-01 | 2012-05-25 |
Subarachnoid Hemorrhage (2) · Aneurysm (1) · Ataxia (1) · Diabetes Mellitus (1) · Multiple Sclerosis (1) · Multiple Sclerosis, Chronic Progressive (1) · Optic Atrophy (1) · Vasospasm, Intracranial (1) · Wolfram Syndrome (1)
University of Massachusetts, Worcester (2) · National Institute of Allergy and Infectious Diseases (NIAID) (1) · Washington University School of Medicine (1)
United States (4)
Susanne Muehlschlegel, MD (2) · Bibiana Bielekova, M.D. (1) · Fumihiko Urano, MD (1) · John R Sims, MD (1)
PMID 21454813, PMID 25344064, PMID 34185708, PMID 40371642
R21DK113487 (1)