4 terminated, 3 unknown, 1 active not recruiting, 1 completed. 5 Phase 2, 2 Early Phase 1, 1 Not applicable, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 5 | Terminated 2, Completed 1, Recruiting 1, Unknown 1 |
| Early Phase 1 | 2 | Active not recruiting 1, Terminated 1 |
| Not applicable | 1 | Terminated 1 |
| Phase 3 | 1 | Unknown 1 |
Follow Cytoreduction: new trials by email Literature Review of Cytoreduction trials Research Report on Cytoreduction
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| SUROVA - Surgery in Ovarian Cancer, Comparing Primary and Interval Cytoreductive Surgery Cytoreductive surgery, Neoadjuvant chemotherapy, Adjuvant chemotherapy - Epithelial Ovarian Cancer, Fallopian Tube Neoplasms | Unknown | Clinica Universidad de Navarra, Universidad de Navarra | 5000 | 2024-01-01 | 2024-01-25 | |
| Hyperthermic Intraperitoneal Chemotherapy With Cisplatin During Surgery or Cisplatin Before Surgery for the Treatment of Stage III or IV Ovarian, Fallopian Tube or Peritoneal Cancer Carboplatin, Cisplatin, Cytoreductive Surgery - Fallopian Tube Endometrioid Adenocarcinoma, Fallopian Tube Mucinous Adenocarcinoma | Early Phase 1 | Active not recruiting | Ohio State University Comprehensive Cancer Center | 35 | 2022-06-13 | 2026-08-17 |
| Chemotherapy With or Without Immunotherapy for Peritoneal Mesothelioma Atezolizumab, Bevacizumab, Biospecimen Collection - Peritoneal Malignant Mesothelioma | Phase 2 | Recruiting | National Cancer Institute (NCI) | 66 | 2022-03-22 | 2026-10-26 |
| Pembrolizumab With or Without Axitinib for Clear Cell Kidney Cancer in Patients Undergoing Surgery Axitinib (VEGF-TKI), Cytoreductive Nephrectomy (CN), Metastasectomy (MET) - Metastatic Clear Cell Renal Cell Carcinoma, Recurrent Clear Cell Renal Cell Carcinoma | Phase 2 | Terminated | University of California, San Francisco | 6 | 2021-02-09 | 2025-11-19 |
| Heated Intra-peritoneal Chemotherapy With Doxorubicin and Cisplatin for Abdominal for Pelvic Tumors in Pediatric Patients Cisplatin, Cytoreductive Surgery, Doxorubicin - Malignant Abdominal Neoplasm, Malignant Pelvic Neoplasm | Early Phase 1 | Terminated | Mayo Clinic | 2 | 2019-11-08 | 2025-02-20 |
| Cytoreductive Surgery and Intraperitoneal Chemotherapy for Stomach CAncer: a Feasibility Study Perioperative chemotherapy, Cytoreduction, HIPEC - Gastric Cancer, Peritoneal Carcinomatosis | Phase 2 | Terminated | Richard van Hillegersberg | 3 | 2017-08-01 | 2019-04-17 |
| Thiotepa, Busulfan and Fludarabin for pt With Refractory/Early Relapsed Aggressive B-cell Non Hodgkin Lymphomas Thiotepa, Busulfan, Fludarabin - B-cell Lymphoma Refractory | Phase 2 | Unknown | Azienda Ospedaliera San Giovanni Battista | 42 | 2013-02-01 | 2014-07-08 |
| Cytoreduction With or Without Intraoperative Intraperitoneal Hyperthermic Chemotherapy (HIPEC) in Patients With Peritoneal Carcinomatosis From Ovarian Cancer, Fallopian Tube or Primary Peritoneal Carcinoma Cytoreduction, Hipec with Cisplatin - Peritoneal Carcinomatosis From Ovarian Cancer, Fallopian Tube Carcinoma | Phase 3 | Unknown | Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia | 32 | 2012-02-01 | 2017-12-13 |
| Hyperthermic Intraoperative Intraperitoneal Chemotherapy of Recurrent Ovarian Cancer - A Feasibility Study Hyperthermic intraoperative intraperitoneal chemotherapy, Cytoreduction, Cisplatin - Epithelial Ovarian Cancer, Fallopian Tube Carcinoma | Not applicable | Terminated | Cantonal Hospital of St. Gallen | 6 | 2008-02-01 | 2023-08-08 |
| S0009 Combination Chemo and Surgery in Stage III or Stage IV Ovarian Cancer carboplatin, paclitaxel, debulking surgery - Fallopian Tube Cancer, Ovarian Cancer | Phase 2 | Completed | SWOG Cancer Research Network | 62 | 2001-03-01 | 2016-01-08 |
Fallopian Tube Neoplasms (6) · Ovarian Neoplasms (5) · Carcinoma, Ovarian Epithelial (3) · Peritoneal Neoplasms (3) · Stomach Neoplasms (2) · Carcinoma, Renal Cell (1) · Clear-cell metastatic renal cell carcinoma (1) · Colonic Neoplasms (1) · Desmoplastic Small Round Cell Tumor (1) · Hyperthermia (1) · Liposarcoma (1) · Mesothelioma, Malignant (1) · Pelvic Neoplasms (1) · Rectal Neoplasms (1) · Recurrence (1)
Azienda Ospedaliera San Giovanni Battista (1) · Cantonal Hospital of St. Gallen (1) · Clinica Universidad de Navarra, Universidad de Navarra (1) · Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia (1) · Mayo Clinic (1) · National Cancer Institute (NCI) (1) · Ohio State University Comprehensive Cancer Center (1) · Richard van Hillegersberg (1) · SWOG Cancer Research Network (1) · University of California, San Francisco (1)
United States (4) · Spain (2) · Italy (1) · Netherlands (1) · Switzerland (1)
Aaron S Mansfield (1) · Amy D. Tiersten, MD (1) · Benedetto Bruno, MD (1) · David Y Oh, MD, PhD (1) · Floor Backes, MD (1) · Jelle P Ruurda, MD PhD (1) · Luis M Chiva, MD, PhD (1) · Patricio C. Gargollo, M.D. (1) · Pedro Cascales Campos, M.D Phd (1) · Richard van Hillegersberg, MD PhD (1)
PMID 19138791, PMID 31069579, PMID 37673112, PMID 38479803, PMID 41352872
2016 (1), U10CA032102 (1), U10CA180821 (1)