9 completed. 9 Phase 2, 4 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 9 | Completed 9 |
| Phase 1 | 4 | Completed 4 |
Follow Cysteamine: new trials by email Literature Review of Cysteamine trials Research Report on Cysteamine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effectiveness of a Bilayering Serum and Cream Containing GABA, DMAE, Cysteamine, and Bakuchiol for Skin Whitening and Anti-Aging GABA, Placebo, DMAE - Skin Aging | Phase 2 | Completed | Hasanuddin University | 44 | 2025-03-12 | 2026-03-24 |
| PK and PD Study of NPI-001 and Cysteamine Bitartrate Cysteamine Bitartrate, N-Acetylcysteine Amide - Cystinosis | Phase 1 / Phase 2 | Completed | Nacuity Pharmaceuticals, Inc. | 8 | 2023-10-29 | 2026-10-13 |
| A Study of the Dosing, Efficacy, and Safety of Oral Cysteamine in Adult Patients With Cystic Fibrosis Exacerbations Cysteamine, Placebo Oral Capsule - Cystic Fibrosis | Phase 2 | Completed | NovaBiotics Ltd. | 91 | 2016-12-01 | 2021-04-14 |
| First Study of Oral Cysteamine in Cystic Fibrosis Cysteamine - Cystic Fibrosis | Phase 1 / Phase 2 | Completed | University of Aberdeen | 10 | 2014-08-01 | 2015-11-05 |
| Open-Label, Dose-Escalating Study Assessing Safety, Tolerability, Efficacy, of RP103 in Mitochondrial Disease Cysteamine Bitartrate - Inherited Mitochondrial Disease, Including Leigh Syndrome | Phase 2 | Completed | Amgen | 36 | 2014-05-01 | 2024-12-27 |
| Pilot Study of Safety, Tolerability, Pharmacokinetics/Pharmacodynamics of RP103 Compared to Cystagon® in Patients With Cystinosis Cystagon®, RP103 - Cystinosis | Phase 1 / Phase 2 | Completed | Amgen | 9 | 2009-05-01 | 2024-12-19 |
| A Preliminary Study to Evaluate Cysteamine Therapy in Human Subjects With Non-Alcoholic Steatohepatitis (NASH) Cysteamine - Fatty Liver | Phase 1 / Phase 2 | Completed | Joel Lavine | 13 | 2008-10-01 | 2014-01-31 |
| Cysteamine Eye Drops to Treat Corneal Crystals in Cystinosis Cysteamine - Cystinosis | Phase 2 | Completed | National Eye Institute (NEI) | 328 | 1986-04-01 | 2014-07-22 |
| A Phase II/III Study of Cysteamine (Mercaptoethylamine) and Zidovudine for the Treatment of HIV Disease Cysteamine, Zidovudine - HIV Infections | Phase 2 | Completed | Mylan Laboratories | 300 | 2005-06-24 |
Cystinosis (3) · Cystic Fibrosis (2) · AIDS-Related Complex (1) · Bacterial Infections (1) · Bronchitis (1) · Epilepsies, Myoclonic (1) · Fatty Liver (1) · HIV Infections (1) · Leigh Disease (1) · Lung Diseases (1) · Mitochondrial Encephalomyopathies (1) · Non-alcoholic Fatty Liver Disease (1) · Ophthalmoplegia, Chronic Progressive External (1) · Optic Atrophy, Hereditary, Leber (1) · Pneumonia (1)
Amgen (2) · Hasanuddin University (1) · Joel Lavine (1) · Mylan Laboratories (1) · Nacuity Pharmaceuticals, Inc. (1) · National Eye Institute (NEI) (1) · NovaBiotics Ltd. (1) · University of Aberdeen (1)
United States (6) · United Kingdom (2) · Australia (1) · Indonesia (1) · Italy (1)
Graham Devereux, MD (1) · Hugh McCarthy, PhD, FRACP (1) · Rachel J Bishop, M.D. (1)
2014 (1)