5 completed, 2 terminated, 1 unknown. 8 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 8 | Completed 5, Terminated 2, Unknown 1 |
Follow Cyclosporin: new trials by email Literature Review of Cyclosporin trials Research Report on Cyclosporin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Rituximab in Treatment of Membranoproliferative Glomerulonephritis Rituximab, Cyclosporin - Membranoproliferative Glomerulonephritis | Phase 3 | Unknown | Assiut University | 30 | 2017-07-01 | 2017-06-16 |
| Graft-Versus-Host Disease Prophylaxis in Treating Patients With Hematologic Malignancies Undergoing Unrelated Donor Peripheral Blood Stem Cell Transplant Allogeneic Hematopoietic Stem Cell Transplantation, Cyclosporine, Fludarabine Phosphate - Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia | Phase 3 | Completed | Fred Hutchinson Cancer Center | 174 | 2010-11-01 | 2026-04-30 |
| Allogeneic HCT Using Nonmyeloablative Host Conditioning With TLI & ATG vs SOC in AML Allogeneic HSCT, Anti-thymocyte globulin (ATG), Cyclosporine (CSP) - Leukemia, Myeloid, Leukemia | Phase 3 | Terminated | Stanford University | 58 | 2007-08-01 | 2019-09-24 |
| Switch From Tacrolimus to Cyclosporin in the Treatment of Recurrent Hepatitis C After Liver Transplantation ciclosporin - Chronic Hepatitis C, Evidence of Liver Transplantation | Phase 3 | Terminated | Rennes University Hospital | 11 | 2006-06-01 | 2012-03-02 |
| Low-Dose or High-Dose Conditioning Followed by Peripheral Blood Stem Cell Transplant in Treating Patients With Myelodysplastic Syndrome or Acute Myelogenous Leukemia total-body irradiation, allogeneic hematopoietic stem cell transplantation, cyclophosphamide - Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome, Acute Myeloid Leukemia/Transient Myeloproliferative Disorder | Phase 3 | Completed | Fred Hutchinson Cancer Center | 25 | 2006-01-01 | 2014-10-31 |
| Focal Segmental Glomerulosclerosis Clinical Trial (FSGS-CT) Cyclosporin, Mycophenolate mofetil and Dexamethasone - Glomerulosclerosis, Focal | Phase 3 | Completed | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | 192 | 2004-11-01 | 2026-09-18 |
| Treatment Protocol for Hemophagocytic Lymphohistiocytosis 2004 Dexamethasone, Etoposide, Cyclosporin - Hemophagocytic Lymphohistiocytosis | Phase 3 | Completed | Karolinska University Hospital | 368 | 2004-01-01 | 2018-07-05 |
| Combination Chemotherapy With or Without Peripheral Stem Cell Transplant in Treating Children With Acute Lymphoblastic Leukemia filgrastim, asparaginase, cyclophosphamide - Childhood Acute Lymphoblastic Leukemia in Remission, Recurrent Childhood Acute Lymphoblastic Leukemia | Phase 3 | Completed | National Cancer Institute (NCI) | 220 | 2002-10-01 | 2014-02-27 |
Leukemia, Myeloid, Acute (3) · Myeloproliferative Disorders (2) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (2) · Chromosome 5q Deletion Syndrome (1) · Congenital Abnormalities (1) · Glomerulonephritis, Membranoproliferative (1) · Glomerulosclerosis, Focal Segmental (1) · Hematologic Neoplasms (1) · Hepatitis C, Chronic (1) · Hodgkin Disease (1) · Leukemia (1) · Leukemia, Lymphocytic, Chronic, B-Cell (1) · Leukemia, Myelogenous, Chronic, BCR-ABL Positive (1) · Leukemia, Myeloid (1) · Leukemia, Prolymphocytic (1)
Fred Hutchinson Cancer Center (2) · Assiut University (1) · Karolinska University Hospital (1) · National Cancer Institute (NCI) (1) · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (1) · Rennes University Hospital (1) · Stanford University (1)
United States (5) · Germany (2) · Denmark (1) · France (1) · Sweden (1)
Aaron Friedman, MD (1) · Bart Scott (1) · Brenda Sandmaier (1) · Eric Bellissant, MD, PhD (1) · Jan-Inge Henter, MD, PhD (1) · Kirk Schultz (1) · Marva Moxey-Mims, MD, FAAP (1) · Robert Lowsky (1) · Yvon Calmus, MD, PhD (1)
PMID 21178977, PMID 21734640, PMID 28935695, PMID 31248843, PMID 32499241, PMID 32780845, PMID 33242441, PMID 33412162, PMID 35224732, PMID 40337980, PMID 42628036
P01CA018029 (2), K23HL084054 (1), P01CA078902 (1), P01HL036444 (1), P30CA015704 (1), U01DK063385 (1), U01DK063455 (1), U01DK063490 (1), U01DK063549 (1), U10CA098543 (1)