33 completed, 17 unknown, 13 terminated, 5 withdrawn. 40 Phase 2, 18 Phase 3, 8 Not applicable, 8 Phase 1, 2 Early Phase 1.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Convalescent Plasma Therapy for Hospitalized Patients With COVID-19 Convalescent plasma, Standard of care - COVID-19, Convalescent Plasma | Phase 2 | Completed | Tânia Portella Costa | 38 | 2022-01-06 | 2023-11-29 |
| COVID-19 Infection in Patients Receiving Anti-CD20 Therapy Convalescent Plasma - COVID-19, Immunosuppressed Host | Completed | Mayo Clinic | 342 | 2021-06-01 | 2023-03-01 | |
| Reconvalescent Plasma/Camostat Mesylate Early in SARS-CoV-2 Q-PCR (COVID-19) Positive High-risk Individuals Convalescent plasma, Camostat Mesilate, Placebo for Camostat Mesilate - Corona Virus Infection, SARS-CoV-2 Infection | Phase 2 | Completed | Heinrich-Heine University, Duesseldorf | 22 | 2021-01-08 | 2022-02-10 |
| Convalescent Plasma for Treating Patients With COVID-19 Pneumonia Without Indication of Ventilatory Support Convalescent plasma - COVID-19 | Phase 2 | Unknown | D'Or Institute for Research and Education | 60 | 2020-12-11 | 2021-08-06 |
| Remdesivir and Convalescent Plasma Therapy for Treatment of COVID-19 Infection in Nepal : A Registry Study Remdesivir - Covid19 | Unknown | Nepal Health Research Council | 2000 | 2020-11-19 | 2020-12-17 | |
| VA CoronavirUs Research and Efficacy Studies-1 Convalescent Plasma, Masked Saline Placebo - COVID-19 | Phase 3 | Terminated | VA Office of Research and Development | 75 | 2020-11-16 | 2022-09-23 |
| Convalescent Plasma as Treatment for Subjects With Early COVID-19 Infection Convalescent Plasma, Best Supportive Care - COVID-19 | Phase 2 | Terminated | Hackensack Meridian Health | 21 | 2020-11-06 | 2023-10-10 |
| Early Convalescent Plasma Therapy for High-risk Patients With COVID-19 in Primary Care (the CoV-Early Study) ConvP, FFP - Covid19 | Phase 3 | Terminated | Erasmus Medical Center | 420 | 2020-10-12 | 2022-04-01 |
| Administration of Anti-SARS-CoV-2 Convalescent Plasma in Hospitalized, Non-ICU Patients With COVID-19 anti-SARS-CoV-2 plasma, Placebo - COVID-19 | Phase 2 | Withdrawn | Kashif Khan | 2020-10-01 | 2020-10-22 | |
| PERUCONPLASMA: Evaluating the Use of Convalescent Plasma as Management of COVID-19 Convalescent plasma - COVID-19 | Phase 2 | Completed | Universidad Peruana Cayetano Heredia | 100 | 2020-09-21 | 2021-10-28 |
| Efficacy of CONvalescent Plasma in Patients With COVID-19 Treated With Mechanical Ventilation Convalescent Plasma, Standard of Care - Covid19, Mechanical Ventilation Complication | Phase 2 | Completed | University of Liege | 475 | 2020-09-11 | 2024-10-29 |
| Safety and Efficacy of Convalescent Plasma Transfusion for Patients With COVID-19 convalescent plasma - COVID-19 | Phase 2 / Phase 3 | Unknown | Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran | 410 | 2020-08-25 | 2020-08-26 |
| Convalescent Plasma in the Early Treatment of High-Risk Patients With SARS-CoV-2 (COVID-19) Infection Convalescent Plasma - Covid19 | Phase 2 | Terminated | Joseph M. Flynn, D.O., MPH | 2 | 2020-08-14 | 2024-10-24 |
| Evaluating the Efficacy of Convalescent Plasma in Symptomatic Outpatients Infected With COVID-19 CCP - COVID-19 | Phase 2 | Completed | Metro Infectious Disease Consultants | 103 | 2020-08-12 | 2022-04-06 |
| Convalescent Plasma in Outpatients With COVID-19 Convalescent Plasma, Saline - Covid19 | Phase 3 | Completed | Stanford University | 511 | 2020-08-11 | 2021-10-19 |
| COVID-19 Convalescent Plasma Therapy Convalescent plasma - SARS-CoV-2 Infection, COVID-19 Infection | Phase 2 / Phase 3 | Completed | Universidad Nacional de Asunción | 350 | 2020-08-10 | 2021-03-02 |
| Therapeutic Plasmapheresis in Critically Ill Adult Patients With COVID-19 Confirmed Diagnosis Convalescent plasma - COVID-19 | Phase 2 | Unknown | Fundación Cardiovascular de Colombia | 44 | 2020-08-01 | 2020-07-22 |
| Clinical Protocol for Convalescent Plasma and Remdesivir Therapy in Nepal Convalescent Plasma - COVID-19 | Unknown | Dr. Pradip Gyanwali,MD | 200 | 2020-07-30 | 2020-09-30 | |
| TranSfUsion of coNvalescent plAsma for the Early Treatment of pneuMonIa in COVID-19 Patients Convalescent plasma - Covid19, Coronavirus Infection | Not applicable | Completed | Istituto Superiore di Sanità | 474 | 2020-07-16 | 2021-08-26 |
| Convalescent Plasma for Severe COVID-19 Patients Convalescent Plasma, Best Supportive Care - Covid19 | Phase 3 | Completed | Hospital de Clinicas de Porto Alegre | 160 | 2020-07-16 | 2021-02-09 |
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COVID-19 (63) · Coronavirus Infections (18) · Severe Acute Respiratory Syndrome (6) · Pneumonia (5) · Convalescence (3) · Respiratory Insufficiency (3) · Community-Acquired Pneumonia (2) · Critical Illness (2) · Pneumonia, Viral (2) · Respiratory Distress Syndrome (2) · Respiratory Tract Diseases (2) · Cytokine Release Syndrome (1) · Hemorrhagic Fever, Ebola (1) · Hyaline Membrane Disease (1) · Influenza, Human (1)
Hackensack Meridian Health (3) · Azienda Socio Sanitaria Territoriale di Mantova (2) · Erasmus Medical Center (2) · Henry Ford Health System (2) · Mayo Clinic (2) · Alkarkh Health Directorate-Baghdad (1) · Azienda Ospedaliero, Universitaria Pisana (1) · Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh (1) · Biofarma (1) · Cairo University (1) · Centro de Hematología y Medicina Interna (1) · D'Or Institute for Research and Education (1) · Dr. Pradip Gyanwali,MD (1) · Fundacin Biomedica Galicia Sur (1) · Fundacion Infant (1)
United States (24) · Mexico (6) · Brazil (5) · Italy (5) · Belgium (4) · India (4) · Nepal (4) · Netherlands (4) · Pakistan (4) · Colombia (3) · Indonesia (3) · Spain (3) · Argentina (2) · Canada (2) · Egypt (2)
Bart Rijnders, MD, PhD (2) · Michele L Donato, MD (2) · Ahmed S Abdulamir, PhD (1) · Alexandre P Zavascki, PhD (1) · Andri MT Lubis, MD, PhD (1) · Angelica Jimenez de Samudio, MD,MSc (1) · Brian Peppers, DO, PhD (1) · Carlos A Gonzalez, MD (1) · Carmen G Torres, MD (1) · Clara Clausen, MD (1) · Clifton W Callaway, MD, PhD (1) · Colin McArthur, Dr (1) · David Hager, MD PhD (1) · Debra J Levan, DO (1) · Derek Angus, Prof (1)
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1OT2HL156812-01 (1), 2015 (1), 2023 (1)