28 completed, 9 unknown, 7 recruiting, 2 not yet recruiting. 31 Not applicable, 5 Phase 4, 4 Phase 2, 4 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 31 | Completed 21, Recruiting 6, Unknown 4 |
| Phase 4 | 5 | Completed 4, Unknown 1 |
| Phase 2 | 4 | Unknown 3, Recruiting 1 |
| Phase 3 | 4 | Not yet recruiting 2, Recruiting 1, Unknown 1 |
Follow connective tissue graft: new trials by email Literature Review of connective tissue graft trials Research Report on connective tissue graft
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Comparative Evaluation of Alb PRF Versus Connective Tissue Graft in Reconstruction of Deficient Interdental Papilla Albumin (5% serum-protein solution containing immunoglobulins), connective tissue graft - Deficient Interdental Papilla | Phase 3 | Not yet recruiting | ahmed mostafa ahmed abo el soud | 28 | 2026-06-20 | 2026-05-19 |
| CTG Versus Collagen Matrix for Peri-Implant Soft Tissue Augmentation Collagen Matrix, Connective Tissue Graft - Peri-implant Soft Tissue Deficiency, Insufficient Peri-implant Keratinized Tissue | Not applicable | Recruiting | Hanoi Medical University | 46 | 2026-01-01 | 2026-09-16 |
| Volume-Stable Collagen Matrix vs. Connective Tissue Graft for Peri-Implant Soft Tissue Defects Connective tissue graft, Volume-stable collagen matrix - Dental Implantation, Peri-Implant Soft Tissue Deficiency | Not applicable | Recruiting | Ankara University | 22 | 2025-12-18 | 2026-08-24 |
| The Effectiveness of Nano Bio Fusion Gingival Gel (NBF) on Wound Healing at the Palate (Donor Site) After Soft Tissue Graft Surgery Compared to Placebo Gel. Application of NBF gel after soft tissue graft surgery, Application of placebo gel after soft tissue graft surgery - Wound Healing, Palatal Wound | Not applicable | Recruiting | King Abdullah University Hospital | 36 | 2025-10-29 | 2026-01-23 |
| A Clinical Comparison of Connective Tissue Graft and Alb-PRF for Rebuilding Interdental Papilla Albumin (5% serum-protein solution containing immunoglobulins), connective tissue graft - Papilla Reconstruction | Phase 3 | Not yet recruiting | shaimaa hamdy | 30 | 2025-09-01 | 2025-08-24 |
| Biofiller and Gingival Phenotype Thickening Biofiller Injection, connective tissue graft - Gingival Recession, Gingival Diseases | Not applicable | Recruiting | Inonu University | 34 | 2025-07-30 | 2025-08-12 |
| Evaluation of the Modified VISTA Technique Using ALB-PRF vs CTG in the Treatment of Multiple Miller Class III Recessions Connective tissue graft, ALB-PRF - Gingival Recession | Phase 2 / Phase 3 | Recruiting | Cairo University | 26 | 2025-04-20 | 2026-03-20 |
| Gingival Recession (RT1) Treatment With Different Gingival Augmentation Surgeries Connective tissue graft, Free gingival graft, Non surgical - Gingival Recession | Not applicable | Recruiting | Misr International University | 30 | 2025-02-05 | 2026-07-06 |
| The Efficacy of Amnion Chorion Allograft in Management of Gingival Recession. Amnion Chorion membrane, connective tissue graft - Gingival Recession, Localized | Phase 4 | Completed | Minia University | 28 | 2024-08-01 | 2025-05-29 |
| Xengenic Cortical Membranes Versus Connective Tissue Graft With Coronally Advanced Flap for the Treatment of Peri-implant Soft Tissue Dehiscences: A Randomized, Controlled Clinical Trial Xengenic Cortical membranes, connective tissue graft - Immediate Implant, Connective Tissue Graft | Phase 2 | Unknown | Amr Anwar Mohamed Ellithy Yousef | 20 | 2024-06-01 | 2024-09-19 |
| Efficacy of Fascia Lata Allograft and Platelet Rich Fibrin on the Periodontal Phenotype Around Dental Implant Fascia lata membrane, Platlet Rich fibrin membrane, subepithelial connective tissue graft - Allograft | Phase 4 | Unknown | Kafrelsheikh University | 24 | 2024-02-01 | 2024-01-23 |
| Modified Periosteal Tissue Graft vs Collagen Matrix for Soft Tissue Augmentation Around Implants: A Comparative Study connective tissue graft, xenogenic collagen membrane - Dental, Implant | Not applicable | Completed | Minia University | 20 | 2024-01-01 | 2025-02-05 |
| Soft Tissue Management in Peri-Implant Regions Connective Tissue Graft, Ribose Cross-Linked Thick Collagen Membrane - Peri-implant Mucosa Thickness, Peri-implant Mucosa Width | Not applicable | Completed | Ömer Alperen Kırmızıgül | 20 | 2023-12-01 | 2025-12-09 |
| Peri-implant Soft Tissue Changes at Small Buccal Dehiscences Connective tissue graft, horizontal guided bone regeneration - Dental Implants | Not applicable | Completed | University of Turin, Italy | 44 | 2023-09-05 | 2026-03-30 |
| Evaluation of Buccal Pedicle Flap, Connective Tissue Graft and Acellular Dermal Matrix for Volumetric Augmentation of Peri-implant Mucosa buccal pedicle flap, connective tissue graft, acellular dermal matrix - Soft Tissue Augmentation Around Dental Implants | Not applicable | Completed | Ghada Elhusseiny | 28 | 2023-06-01 | 2024-06-28 |
| Comparison of Connective Tissue Graft Versus Titanium Papillary Inserts in the Surgical Reconstruction of Interdental Papilla. TITANIUM INSERTS, CONNECTIVE TISSUE GRAFT - Papilla Reconstruction | Not applicable | Completed | Dr R Viswa Chandra | 18 | 2023-05-21 | 2026-02-10 |
| Implants Placement with Simultaneous Soft Tissue Augmentation Using a Collagen Matrix Compared to Connective Tissue Graft: a Pilot Study dental implant, Fibrogide membrane, connective tissue graft - Soft Tissue Thickness Arround Implants | Phase 4 | Completed | Saint-Joseph University | 4 | 2022-10-10 | 2024-09-19 |
| Vestibular Socket Therapy Using Acellular Dermal Matrix Versus Connective Tissue Graft implant, Vestibular Socket Therapy, Alloderm - Immediate Implant | Phase 2 | Unknown | Tanta University | 10 | 2022-07-01 | 2024-02-05 |
| CTG vs VCMX for Peri-implant Soft Tissue Thickness Connective Tissue Graft, Volume-Stable Collagen Matrix - Dental Implants, Peri-Implant Tissues | Not applicable | Completed | Medical Innovation Center Wroclaw | 36 | 2022-01-02 | 2026-01-16 |
| Keratized Mucosa in CG Implant Placement: CTG vs Flapless Connective tissue graft, Flapless - Variation of Keratinized Mucosa After Implant Surgery | Not applicable | Recruiting | University of Milan | 44 | 2021-10-18 | 2021-12-03 |
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Gingival Recession (21) · Anodontia (1) · Gingival Diseases (1) · Gingivitis (1) · Pain, Postoperative (1) · Peri-Implantitis (1) · Periodontal Diseases (1) · Tooth Abrasion (1) · Tooth Fractures (1) · Tooth Loss (1)
Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University (3) · Universidade Estadual Paulista Júlio de Mesquita Filho (3) · Ege University (2) · Minia University (2) · Abeer hassan sharafuddin (1) · Amr Anwar Mohamed Ellithy Yousef (1) · Ankara University (1) · Bulent Ecevit University (1) · Cairo University (1) · Centre Hospitalier Universitaire de Liege (1) · Columbia University (1) · Damascus University (1) · Dr R Viswa Chandra (1) · Geistlich Pharma AG (1) · Ghada Elhusseiny (1)
Egypt (9) · Turkey (Türkiye) (7) · Brazil (5) · China (3) · Italy (3) · India (2) · Belgium (1) · Iran (1) · Jordan (1) · Lebanon (1) · Poland (1) · Switzerland (1) · Syria (1) · Vietnam (1)
Mauro P Santamaria, PhD (2) · Ahmed Khalil, professor (1) · Aya Mohammed, Lecturer (1) · Elcio Marcantonio Jr, Professor (1) · Enji EA Ahmed, BDS.MDS.PHD (1) · Evanthia Lalla, DDS (1) · Ghada A. Elhusseiny, PHD (1) · Giuseppe Romito, PhD (1) · Haydar Barakat, DDS MSc (1) · Heba Ah Abdel-maged, MSc (1) · Karyna M Menezes, Master (1)
PMID 19678861, PMID 20350159, PMID 20367099, PMID 21557757, PMID 23050490, PMID 25363203, PMID 25644301, PMID 27310522, PMID 27834120, PMID 28000280, PMID 28548210, PMID 29293010, PMID 30211382, PMID 31087334, PMID 31461778, PMID 32011032, PMID 32392401, PMID 32710810, PMID 33830339, PMID 34072698, PMID 34287902, PMID 34818383, PMID 35505571, PMID 35796801, PMID 35904229, PMID 35950734, PMID 36935199, PMID 37346848, PMID 37552200, PMID 37750532, PMID 38704784, PMID 39604639, PMID 41382211, PMID 7832683, PMID 9051957