12 unknown, 7 completed, 1 active not recruiting, 1 recruiting. 6 Phase 4, 5 Phase 2, 4 Not applicable, 3 Early Phase 1, 1 Phase 3.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Biological Changes in Fibrovascular Membranes of Patients With Proliferative Diabetic Retinopathy Following Faricimab Injection conbercept ophthalmic injection （0.5mg）, Faricimab - Proliferative Diabetic Retinopathy | Not applicable | Completed | Bojie Hu | 8 | 2024-12-01 | 2025-08-28 |
| Efficacy and Safety of Low-dose Conbercept for Retinopathy of Prematurity Therapy Conbercept - Retinopathy of Prematurity (ROP) | Not applicable | Recruiting | Wang Yusheng | 146 | 2024-11-29 | 2026-07-30 |
| Efficacy and Safety of Conbercept for Diabetic Macular Edema Combined With Severe Non-proliferative Diabetic Retinopathy Conbercept - Diabetic Macular Edema | Phase 4 | Active not recruiting | Shanghai Eye Disease Prevention and Treatment Center | 58 | 2024-04-01 | 2025-05-30 |
| Anti-VEGF in Real-world Ranibizumab, Aflibercept, Conbercept - Neovascular Age-related Macular Edema, Diabetic Macular Edema | Unknown | Wenbin Wei | 1000 | 2022-01-01 | 2022-02-03 | |
| Evaluation of RC28-E Injection in Diabetic Macular Edema intravitreal injection of RC28-E, Conbercept - Diabetic Macular Edema | Phase 2 | Completed | RemeGen Co., Ltd. | 156 | 2021-03-17 | 2023-12-18 |
| Effects of Adding Triamcinolone Acetonide to Conbercept Treatment for Refractory Diabetic Macular Edema (CONTE) Conbercept and TA, Conbercept - Diabetes Mellitus, Type 2, Macular Edema | Not applicable | Unknown | Zhongshan Ophthalmic Center, Sun Yat-sen University | 50 | 2020-11-12 | 2020-11-17 |
| PRP vs PRP+IVC for Severe nPDR Conbercept, Panretinal coagulation - Severe Nonproliferative Diabetic Retinopathy, Diabetic Retinopathy | Not applicable | Unknown | Ruijin Hospital | 40 | 2019-01-18 | 2019-03-05 |
| Safety and Effectiveness of Intravitreal Conbercept for Exudative Circumscribed Choroidal Haemangioma conbercept - Circumscribed Choroidal Haemangioma | Early Phase 1 | Unknown | Sun Yat-sen University | 50 | 2018-06-06 | 2018-06-27 |
| Conbercept for Polypoidal Choroidal Vasculopathy（START Study） Conbercept - Polypoidal Choroidal Vasculopathy, Conbercept | Completed | Peking Union Medical College Hospital | 500 | 2018-05-01 | 2022-02-08 | |
| Initial Versus Delayed PDT Combination With Conbercept in PCV conbercept, Initial PDT, Delayed PDT - Polypoidal Choroidal Vasculopathy | Phase 4 | Completed | The Eye Hospital of Wenzhou Medical University | 80 | 2017-01-01 | 2019-07-19 |
| Intravitreal Conbercept After Vitrectomy Conbercept - Early Proliferative Diabetic Retinopathy | Early Phase 1 | Completed | Tianjin Medical University Eye Hospital | 50 | 2017-01-01 | 2019-04-30 |
| Conbercept in Choroidal Neovascularization Secondary to Uveitis Conbercept, sham - Choroidal Neovascularization, Uveitis | Phase 2 | Unknown | Chongqing Medical University | 40 | 2016-11-01 | 2016-10-17 |
| Efficacy and Safety of "Treat-and-Extend" Regimen Versus "Pro Re Nata" of Conbercept in Age-related Macular Degeneration Treat-and-Extend regimen, Pro Re Nata, Conbercept - Age-related Macular Degeneration | Phase 4 | Unknown | Xiaodong Sun | 141 | 2016-09-01 | 2020-05-19 |
| Conbercept Injection in Treatment of Severe Proliferative Diabetic Retinopathy Conbercept - Proliferative Diabetic Retinopathy, Tractional Retinal Detachment | Phase 4 | Completed | Ruijin Hospital | 112 | 2016-07-01 | 2019-11-21 |
| Intravitreal Conbercept for Idiopathic Choroidal Neovascularization conbercept - Idiopathic Choroidal Neovascularization | Phase 2 | Unknown | Jiao Mingfei | 50 | 2016-06-01 | 2016-08-11 |
| Head to Head Study of Anti-VEGF Treatment. ranibizumab, Conbercept - Age-related Macular Degeneration | Phase 4 | Completed | Novartis Pharmaceuticals | 12 | 2016-01-13 | 2017-11-30 |
| The Efficacy Assessment of Intravitreal Injection of Conbercept in Patients With Polypoidal Choroidal Vasculopathy (PCV) Conbercept - Polypoidal Choroidal Vasculopathy (PCV) | Phase 4 | Unknown | Chengdu Kanghong Biotech Co., Ltd. | 300 | 2015-10-01 | 2017-07-19 |
| Application of Intravitreal Conbercept Injection as a Primary Treatment for Exudative Circumscribed Choroidal Haemangioma conbercept - Circumscribed Choroidal Haemangioma | Early Phase 1 | Unknown | Sun Yat-sen University | 50 | 2014-08-28 | 2019-06-04 |
| Safety and Efficacy Study of Conbercept in Diabetic Macular Edema (DME) (Sailing) Conbercept, Sham injection, Laser - Diabetic Macular Edema | Phase 3 | Unknown | Chengdu Kanghong Biotech Co., Ltd. | 248 | 2014-07-01 | 2016-01-06 |
| Efficacy and Safety of Conbercept in Macular Edema Secondary to Retinal Vein Occlusion Conbercept - Retinal Vein Occlusion | Phase 2 | Unknown | Chengdu Kanghong Biotech Co., Ltd. | 60 | 2012-05-01 | 2014-03-27 |
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Polypoidal Choroidal Vasculopathy (3) · Macular Degeneration (2) · Retinal Vein Occlusion (2) · Choroidal Neovascularization (1) · Diabetes Mellitus (1) · Diabetes Mellitus, Type 2 (1) · Diabetic Retinopathy (1) · Macular Edema (1) · Retinopathy of Prematurity (1) · Uveitis (1)
Chengdu Kanghong Biotech Co., Ltd. (4) · Ruijin Hospital (2) · Sun Yat-sen University (2) · Bojie Hu (1) · Chongqing Medical University (1) · Jiao Mingfei (1) · Novartis Pharmaceuticals (1) · Peking Union Medical College Hospital (1) · RemeGen Co., Ltd. (1) · Shanghai Eye Disease Prevention and Treatment Center (1) · The Eye Hospital of Wenzhou Medical University (1) · Tianjin Medical University Eye Hospital (1) · Wang Yusheng (1) · Wenbin Wei (1) · Xiaodong Sun (1)
China (19)
Chenjin Jin, Ph.D. (2) · Bingqian Liu, MD, PhD (1) · Qiong Zhang, MD (1) · Rong X Li, MD,PhD (1) · Tao Sun (1) · Wenbin Wei, MD (1) · Xi Shen, MD (1) · Xi Shen, PhD (1) · Xiaodong Sun (1) · Xiaoling Liu, Professor (1) · Youxin Chen, Professor (1)
PMID 21438852, PMID 23706949, PMID 28902334, PMID 29104958, PMID 29127949, PMID 34001667, PMID 35223882, PMID 35795633, PMID 37021018, PMID 39207600, PMID 40122579