17 completed, 2 recruiting, 1 not yet recruiting, 1 unknown. 22 Phase 3, 6 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 22 | Completed 17, Recruiting 2, Not yet recruiting 1, Unknown 1, Withdrawn 1 |
| Phase 2 | 6 | Completed 2, Not yet recruiting 1, Recruiting 1, Unknown 1, Withdrawn 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study of Vaccines Against Bundibugyo Virus Disease in Contacts of Cases in the Democratic Republic of the Congo Candidate BDBV vaccine, Active comparator - Ebola Hemorrhagic Fever, Bundibugyo Virus Disease | Phase 2 / Phase 3 | Not yet recruiting | Jean-Pierre Van geertruyden | 3620 | 2026-10-20 | 2026-10-05 |
| The Effects of Remimazolam on Cerebral Blood Flow Following General Anesthesia Induction Remimazolam, Propofol (Group P) - Cerebral Blood Flow | Phase 3 | Completed | Jun Zhang | 52 | 2025-12-29 | 2026-04-15 |
| Study to Evaluate the Efficacy and Safety of DW1807 in Perennial Allergic Rhinitis Patients With Asthma Experimental, Comparator - Perennial Allergic Rhinitis Accompanied by Asthma | Phase 3 | Recruiting | Daewon Pharmaceutical Co., Ltd. | 274 | 2024-09-09 | 2025-09-11 |
| SC1011 Twice Daily vs Placebo in Patients Diagnosed With Idiopathic Pulmonary Fibrosis (IPF) SC1011, Placebo comparator - Idiopathic Pulmonary Fibrosis | Phase 2 / Phase 3 | Recruiting | Guangzhou JOYO Pharma Co., Ltd | 210 | 2023-06-06 | 2024-11-19 |
| 177Lu-PSMA-617 vs. Androgen Receptor-Directed Therapy in the Treatment of Progressive Metastatic Castrate Resistant Prostate Cancer 177Lu-PSMA-617, 68Ga-PSMA-11, ARDT - Prostatic Neoplasms | Phase 3 | Completed | Novartis Pharmaceuticals | 469 | 2021-06-15 | 2026-11-04 |
| An Efficacy, Immunogenicity and Safety Study Investigating an Adjuvanted SARS-CoV-2 Influenza Vaccine to Protect Against COVID-19 in Adults Over Aged 18 Years-old and Older Adjuvanted SARS-CoV-2 Subunit vaccine (aCoV2), Comparator - Influenza | Phase 2 / Phase 3 | Withdrawn | Seqirus | 2020-12-15 | 2021-03-23 | |
| Efficacy Study With QIVc in Pediatric Subjects QIVc, Comparator - Influenza, Human | Phase 3 | Completed | Seqirus | 5723 | 2019-05-13 | 2025-03-04 |
| A Study of Safety and Efficacy of MK-1986 (Tedizolid Phosphate) and Comparator in Participants From Birth to Less Than 12 Years of Age With Acute Bacterial Skin and Skin Structure Infections (MK-1986-018) Tedizolid phosphate, Comparator - Acute Bacterial Skin and Skin Structure Infections | Phase 3 | Completed | Merck Sharp & Dohme LLC | 100 | 2019-01-20 | 2025-07-31 |
| Efficacy & Safety of SmofKabiven Emulsion for Infusion vs Hospital Compounded "All in One" for Parenteral Nutrition SmofKabiven emulsion for infusion, Hospital compounded "All in one" emulsion - Parenteral Nutrition, Surgery | Phase 3 | Completed | Fresenius Kabi | 273 | 2019-01-03 | 2021-08-02 |
| AMZ001 for the Treatment of Knee Osteoarthritis Symptoms AMZ001, Placebo, Comparator - Osteoarthritis, Knee | Phase 2 / Phase 3 | Completed | Amzell | 444 | 2018-10-04 | 2020-10-06 |
| Efficacy and Safety of SmofKabiven Peripheral Versus Compounded Emulsion SmofKabiven Peripheral, Hospital compounded emulsion - Parenteral Feeding, Surgery | Phase 3 | Completed | Fresenius Kabi | 272 | 2017-12-21 | 2021-08-02 |
| A Study of GC1111 in Hunter Syndrom Patients GC1111, Comparator - Hunter Syndrome | Phase 3 | Completed | Green Cross Corporation | 32 | 2017-03-09 | 2024-04-16 |
| Immune Effect of Dexmedetomidine in Patients Undergoing to Spinal Fusion Dexmedetomidine intervention, Placebo - Spine; Arthrosis, Spondylolysis | Phase 2 / Phase 3 | Unknown | Sarah Network of Rehabilitation Hospitals | 46 | 2016-08-01 | 2016-08-23 |
| Abatacept Reversing Subclinical Inflammation as Measured by MRI in ACPA Positive Arthralgia Abatacept, Placebo - Arthralgia, Arthritis | Phase 3 | Completed | University of Erlangen-Nürnberg Medical School | 98 | 2014-11-01 | 2020-03-10 |
| Fine Particle pMDI Formoterol/Beclomethasone in Asthmatics With and Without Spacer: Comparative Efficacy Evaluation Spacer, Comparator - Asthma | Phase 3 | Completed | Universidade Federal de Pernambuco | 45 | 2011-04-01 | 2015-03-31 |
| Study on DMMET-01 Versus Metformin on Improvement of Metabolic Control in Naive Type 2 Diabetes Patients DMMET-01, Metformin Hydrochloride - Diabetes Type 2 | Phase 2 / Phase 3 | Completed | Laboratorios Silanes S.A. de C.V. | 20 | 2009-03-01 | 2010-05-18 |
| Multicenter Trial of Sublingual Immunotherapy With a Solution of Grass Pollen Allergen Extract in Children Grass pollen allergens in a water/glycerol solution, Placebo - Allergic Rhinoconjunctivitis | Phase 3 | Completed | Allergopharma GmbH & Co. KG | 207 | 2008-02-01 | 2015-10-16 |
| Safety and Efficacy of Specific Immunotherapy With an Aluminium Hydroxide-adsorbed Allergoid Preparation of Birch Pollen Allergens Birch pollen allergoid, Placebo - Pollen Allergy | Phase 3 | Completed | Allergopharma GmbH & Co. KG | 253 | 2005-06-01 | 2014-07-03 |
| Safety and Efficacy of House Dust Mite Allergoid in the Treatment of Bronchial Asthma Acaroid, Placebo - Respiratory Hypersensitivity | Phase 3 | Completed | Allergopharma GmbH & Co. KG | 130 | 2005-05-01 | 2015-01-15 |
| Safety and Efficacy of a Sublingual Specific Immunotherapy With an Extract of a Six Grass Pollen Mixture Grass pollen formulation, Comparator - Grass Pollen Allergy | Phase 3 | Completed | Allergopharma GmbH & Co. KG | 160 | 2003-02-01 | 2014-01-24 |
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Asthma (3) · Influenza, Human (2) · Ankylosis (1) · Arthralgia (1) · Arthritis (1) · Diabetes Mellitus, Type 2 (1) · Diabetic Foot (1) · Dust Mite Allergy (1) · Hemorrhagic Fever, Ebola (1) · Hemorrhagic Fevers, Viral (1) · Hyperphagia (1) · Hypersensitivity (1) · Idiopathic Pulmonary Fibrosis (1) · Lung Diseases (1) · Mucopolysaccharidosis II (1)
Allergopharma GmbH & Co. KG (5) · Fresenius Kabi (2) · Seqirus (2) · Amzell (1) · Daewon Pharmaceutical Co., Ltd. (1) · Green Cross Corporation (1) · Guangzhou JOYO Pharma Co., Ltd (1) · Jean-Pierre Van geertruyden (1) · Jun Zhang (1) · Laboratorios Silanes S.A. de C.V. (1) · Merck Sharp & Dohme LLC (1) · Novartis Pharmaceuticals (1) · Organogenesis (1) · Sarah Network of Rehabilitation Hospitals (1) · Universidade Federal de Pernambuco (1)
Germany (8) · China (4) · United States (4) · Brazil (3) · Czechia (3) · Poland (3) · Bulgaria (2) · Latvia (2) · Mexico (2) · South Africa (2) · South Korea (2) · Ukraine (2) · Austria (1) · Bangladesh (1) · Belgium (1)
Annemie Narkus, M.D. (3) · DongKyu Jin, M.D., Ph.D. (1) · Georg Schett, Prof. Dr. univ. (1) · Jose A Rizzo, PhD, MD (1) · Jun Zhang (1) · Luciano P Miranda (1) · Ludger Klimek, M.D. (1) · Ulrich Wahn, MD (1) · William A Marston, MD (1)
PMID 12766097, PMID 15876311, PMID 17274520, PMID 17523386, PMID 18426146, PMID 20624650, PMID 22939758, PMID 39293462, PMID 40233296, PMID 40441170, PMID 40680993, PMID 41962984
2004 (1), 2005 (1), 2016 (1), 2018 (1), 2023 (1)