28 completed, 3 not yet recruiting, 3 withdrawn, 2 terminated. 40 Phase 2, 11 Phase 3, 4 Phase 1.
Follow coenzyme Q10: new trials by email Literature Review of coenzyme Q10 trials Research Report on coenzyme Q10
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| COQ10 and Vitamin E for Off-Target Radiation Toxicity Coenzyme Q10 Cap/Tab, Vitamin E Cap/Tab - Prostate Cancer, Uterine Cancer | Phase 1 / Phase 2 | Not yet recruiting | University of Nebraska | 200 | 2026-12-01 | 2026-10-08 |
| Mitigating Toxic Impact: The Role of Coenzyme Q10 in Post-Exposure Protection Ubiquinone 100 mg Oral Soft Gel, Placebo - Toxicant Induced Chronic Multisymptom Illness and Associated Symptoms and Comorbidities | Phase 2 | Not yet recruiting | University of California, San Diego | 20 | 2026-05-15 | 2026-05-01 |
| Renoprotective Role of Vitamin C and Coenzyme Q10 in Nephrotoxicity Vitamin C, Coenzyme Q 10 - Nephrotoxicity | Phase 2 / Phase 3 | Not yet recruiting | Ain Shams University | 75 | 2026-04-20 | 2026-03-17 |
| Coenzyme Q10 for Neuroprotection in Paclitaxel-Induced Neuropathy Coenzyme Q 10, Paclitaxel - Breast Cancer | Phase 2 | Completed | Damanhour University | 50 | 2025-11-10 | 2026-04-08 |
| Coenzyme Q10 and Chemotherapeutic Toxicity in Breast Cancer Patients Placebo, Coenzyme Q10 200mg twice daily - Breast Cancer, Chemotherapeutic Toxicity | Phase 2 | Completed | Damanhour University | 40 | 2024-08-01 | 2025-12-26 |
| Prevent Cardiac Surgery Associated AKI Trial CoQ10 1200 mg orally with Glutathione 1000 mg orally, Group B: Placebo CoQ10 orally and Placebo Glutathione orally - Renal Failure, Coronary Artery Disease | Phase 2 | Recruiting | George Washington University | 242 | 2024-07-18 | 2026-10-14 |
| The Effect of Co-enzyme Q10 on the Clinical Outcome of Pediatric Patients With Systemic Lupus Erythematosus Coenzyme Q10 - Systemic Lupus Erythematosus | Phase 2 | Completed | Ain Shams University | 60 | 2024-01-01 | 2026-03-12 |
| Coenzyme Q10 and Dentoalveolar Cyst Coenzyme Q10, control group - Cyst, Jaw | Phase 2 | Active not recruiting | Fayoum University | 20 | 2023-06-11 | 2025-03-03 |
| Mitochondrial Complex I Dysfunction in PWS Coenzyme Q10, Placebo - Prader-Willi Syndrome | Phase 2 | Withdrawn | The Hospital for Sick Children | 2023-06-01 | 2024-06-18 | |
| Coenzyme Q10 in Juvenile Idiopathic Arthritis Patients Coenzyme Q10, Placebo, Standard Regimen - Juvenile Idiopathic Arthritis | Phase 2 / Phase 3 | Unknown | Nourhan Elsherif | 60 | 2023-05-01 | 2023-05-31 |
| Effect of Montelukast Versus Co Enzyme in Sepsis Montelukast Sodium 10 mg, Co-Enzyme Q10, Standard Treatment - Sepsis | Phase 2 / Phase 3 | Completed | Ain Shams University | 90 | 2022-02-01 | 2023-07-20 |
| Coenzyme Q10 as Treatment for Long Term COVID-19 Coenzyme Q10, Placebo - Covid19, Long Term Covid19 | Phase 2 | Completed | Aarhus University Hospital | 121 | 2021-05-25 | 2022-05-06 |
| Trial of Nicotinamide Riboside and Co-enzyme Q10 in Chronic Kidney Disease CoQ10, Nicotinamide riboside, Placebo - Chronic Kidney Disease, Sarcopenia | Phase 2 | Completed | University of Washington | 26 | 2018-11-14 | 2023-01-10 |
| Statin Monotherapy for Treatment of Endocrine Metabolic Disease Risk Rosuvastatin Calcium, Placebo Oral Tablet, Coenzyme Q10 - Spinal Cord Injuries, Osteoporosis | Phase 2 | Terminated | Dr. B. Catharine. Craven | 8 | 2018-02-26 | 2026-04-13 |
| CoQ10 and D-ribose in Patients With Diastolic Heart Failure CoQ10, D-Ribose Oral Powder, Placebo pills - Heart Failure, Diastolic | Phase 2 | Completed | University of Kansas Medical Center | 216 | 2018-02-05 | 2022-03-18 |
| Efficacy of Coenzyme q10 in Pediatrics With Type 1 Diabetes Mellitus Coenzyme Q10, Insulin - Diabetes Mellitus, Type 1 | Phase 2 | Completed | Ain Shams University | 49 | 2017-03-19 | 2018-04-03 |
| BPM31510 Administered Intravenously With Gemcitabine in Advanced Pancreatic Cancer Patients BPM31510 Nanosuspension Injection, Gemcitabine - Pancreatic Cancer | Phase 2 | Completed | BPGbio | 45 | 2016-07-06 | 2025-03-26 |
| Ubiquinol Treatment in Patients With Heart Failure and Preserved Ejection Fraction ubiquinol, Placebo - Heart Failure | Phase 2 | Unknown | Hadassah Medical Organization | 60 | 2016-07-01 | 2016-05-20 |
| Ubiquinol as a Metabolic Resuscitator in Post-Cardiac Arrest Ubiquinol, Ensure - Cardiac Arrest | Phase 2 | Completed | Beth Israel Deaconess Medical Center | 48 | 2016-03-01 | 2021-02-15 |
| Immediate or Delayed Naturopathic Medicine in Combination With Neo-Adjuvant Chemotherapy for Breast Cancer Reishi mushroom extract, Coenzyme Q10, Melatonin - Quality of Life | Phase 1 / Phase 2 | Terminated | Midwestern Regional Medical Center | 5 | 2016-02-19 | 2018-08-01 |
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Coronary Artery Disease (3) · Parkinson Disease (3) · Breast Neoplasms (2) · Fatigue (2) · Heart Arrest (2) · Mitochondrial Diseases (2) · Muscular Dystrophy, Duchenne (2) · Neoplasms (2) · Pain (2) · Supranuclear Palsy, Progressive (2) · Amyotrophic Lateral Sclerosis (1) · Anemia, Refractory, with Excess of Blasts (1) · Anus Neoplasms (1) · Arthritis, Juvenile (1) · Asthenia (1)
Ain Shams University (4) · Taichung Veterans General Hospital (3) · Beth Israel Deaconess Medical Center (2) · Cooperative International Neuromuscular Research Group (2) · Damanhour University (2) · Hadassah Medical Organization (2) · Aarhus University Hospital (1) · BPGbio (1) · Catherine Buettner (1) · Columbia University (1) · Dr. B. Catharine. Craven (1) · Fayoum University (1) · George Washington University (1) · German Parkinson Study Group (GPS) (1) · Hospital Universitari Vall d'Hebron Research Institute (1)
United States (19) · Egypt (8) · Canada (3) · Taiwan (3) · Australia (1) · Denmark (1) · Germany (1) · Israel (1) · Japan (1) · Mexico (1) · Singapore (1) · Spain (1) · United Kingdom (1)
Adolfo D. Rodriguez-Carrizalez, M.Sc. (1) · Ahmed Ashour, PhD (1) · Amira B Kassem, PhD (1) · B. Catharine Craven, BA, MD, FRCPC, MSc (1) · Baback Roshanravan, MD (1) · Barbara Tilley, Ph.D. (1) · Beatrice A. Golomb, MD, PhD (1) · Bryan Kestenbaum, MD (1) · Catherine Buettner, MD, MPH (1) · Chi P Lin, MD (1) · Christina Shannon, ND (1) · Christopher A Ross, MD, PhD (1) · Clifford W. Shults, M.D. (1) · David Leibowitz, MD (1)
PMID 19743457, PMID 22595020, PMID 24192015, PMID 24711047, PMID 25386668, PMID 26212172, PMID 27051670, PMID 27716246, PMID 29606104, PMID 34826125, PMID 35644694, PMID 36337437, PMID 37159264, PMID 39847432, PMID 40845766, PMID 41958203, PMID 42401951
2016 (1), K23AR055664 (1), R01AG054486 (1), R01DK101509 (1), R01NS048125 (1), U01NS043128 (1)