22 completed, 3 terminated, 3 unknown, 2 withdrawn. 10 Phase 3, 8 Phase 4, 5 Not applicable, 4 Phase 2, 2 Phase 1.
Follow ChloraPrep: new trials by email Literature Review of ChloraPrep trials Research Report on ChloraPrep
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Aqueous vs Alcohol Chlorhexidine Skin Preparation for Prevention of Cesarean Section Wound Infections 2% Chlorhexidine gluconate with 70% alcohol, 4% Chlorhexidine Gluconate aqueous solution - Surgical Site Infection, Cesarean Section; Infection | Phase 4 | Completed | Hyagriv Simhan | 1398 | 2023-10-09 | 2026-01-07 |
| Perioperative Patient Skin Antiseptic Preparation Evaluation 70% v/v Isopropyl Alcohol Surgical Solution, 2%w/v Chlorhexidine Gluconate / 70% v/v Isopropyl Alcohol - Surgical Site Infection | Phase 3 | Completed | Zurex Pharma, Inc. | 51 | 2021-06-21 | 2024-03-20 |
| Comparison Trial for Chloraprep Versus Aqueous Chlorhexidine (2%) for the Prevention of Catheter-related Bacteremia A (Chloraprep), B (Clorhexidine 2%) - Sepsis Affecting Skin, Central Venous Catheter Related Bacteremia | Phase 4 | Withdrawn | Instituto de Investigacion Sanitaria La Fe | 2019-10-01 | 2020-06-11 | |
| Comparison of Two Preoperative Antiseptic Solutions Alcohol Based in Abdominal Elective Surgeries Iodine Povacrylex 7 MG/ML / Isopropyl Alcohol 0.74 ML/ML, Chlorhexidine Gluconate 20 MG/ML / Isopropyl Alcohol 0.7 ML/ML - Surgical Site Infection | Phase 4 | Terminated | Universidad de El Salvador | 18 | 2019-04-05 | 2023-05-10 |
| ROSSINI 2 - Reduction of Surgical Site Infection Using Several Novel Interventions 2% alcoholic chlorhexidine skin prep (SKIN PREP), Iodophor Antimicrobial Incise Drapes (DRAPE), Gentamicin-impregnated implants/ sponges (SPONGE) - Surgical Site Infection, Surgical Wound Infection | Phase 3 | Unknown | University of Birmingham | 6610 | 2019-03-01 | 2022-11-28 |
| In-vivo Efficacy of Patient Preoperative Prep, ZuraPrep (ZP) ZuraPrep Clear Solution, ChloraPrep, ZuraPrep Vehicle - Surgical Skin Preparation | Phase 3 | Completed | Zurex Pharma, Inc. | 156 | 2019-01-25 | 2023-02-08 |
| Pre-operative Alcohol Skin Solutions in Fractured Extremities DuraPrep, ChloraPrep - Surgical Site Infection, Unplanned Fracture-Related Reoperation | Phase 4 | Completed | University of Maryland, Baltimore | 8485 | 2018-08-21 | 2024-10-04 |
| An Evaluation of the Efficacy of HEXI-PREP by Clinell Wipes HEXI-PREP By Clinell Wipes, Chloraprep, Placebos - Antimicrobial Effect | Phase 3 | Completed | Gama Healthcare Ltd. | 93 | 2018-06-29 | 2020-07-22 |
| Effectiveness of an Antimicrobial Agent for Preoperative Skin Preparation OCT - clear, OCT- tinted, ChloraPrep - Preoperative Skin Preparation | Phase 2 | Completed | Becton, Dickinson and Company | 131 | 2017-06-21 | 2021-04-23 |
| In Vivo Preoperative Skin Preparation Persistence Evaluation 3M CHG/IPA Prep, ChloraPrep - Bacterial Recovery of Skin Flora Post-product Application | Phase 2 | Completed | Solventum US LLC | 69 | 2016-12-05 | 2024-10-02 |
| Clinical Evaluation of Patient Preoperative Prep ZuraPrep, ChloraPrep, ZP Vehicle - Surgical Skin Preparation | Phase 3 | Completed | Zurex Pharma, Inc. | 640 | 2016-08-03 | 2021-07-16 |
| In-vivo Efficacy of Patient Preoperative Prep ZuraPrep, ChloraPrep, ZP Vehicle - Surgical Skin Preparation | Phase 3 | Completed | Zurex Pharma, Inc. | 440 | 2016-07-27 | 2023-02-08 |
| Prevention of Surgical Site Infection After Cesarean Delivery Chlorhexidine-alcohol group, Povidone-Iodine Group - Surgical Site Infection | Not applicable | Withdrawn | Brigham and Women's Hospital | 2015-06-01 | 2016-01-12 | |
| Efficacy Study to Evaluate Antimicrobial Effectiveness of ZuraPrep™ (ZX-ZP-0055) ZuraPrep, ChloraPrep - Surgical Site Infection | Phase 2 | Completed | Zurex Pharma, Inc. | 36 | 2014-11-01 | 2016-07-14 |
| Efficacy of Surgical Skin Preparation Solutions in Hip Arthroplasty Surgery DuraPrep, ChloraPrep - Arthroplasty, Hip Replacement, Infection, Postoperative Wound | Not applicable | Completed | Lakehead University | 105 | 2014-10-29 | 2019-07-01 |
| Efficacy Study to Evaluate Antimicrobial Effectiveness of ZuraPrep™ Chloraprep, ZuraPrep, ZuraPrep Vehicle - Surgical Site Infection | Phase 2 | Terminated | Zurex Pharma, Inc. | 64 | 2014-08-01 | 2016-07-18 |
| Safety Study to Evaluate the Contact Sensitizing Potential of Topically Applied ZuraPrep™ and ZuraPrep™ Without IPA Chloraprep, 0.9% Physiological Saline, ZuraPrep without IPA - Surgical Site Infection | Phase 1 | Completed | Zurex Pharma, Inc. | 208 | 2014-07-01 | 2015-03-17 |
| In Vivo Efficacy Study of Patient Preoperative Preps 3M CHG/IPA Prep C, 3M CHG/IPA Prep CH, ChloraPrep - Bacterial Reduction Post-product Application | Phase 3 | Completed | 3M | 738 | 2014-07-01 | 2020-11-23 |
| Safety Study to Evaluate the Cumulative Irritation Potential of Topically Applied ZuraPrep™ and ZuraPrep™ Without IPA ChloraPrep, 0.1% Sodium Lauryl Sulfate, 0.9% Physiological Saline - Surgical Site Infection | Phase 1 | Completed | Zurex Pharma, Inc. | 40 | 2014-06-01 | 2014-10-27 |
| Chlorhexidine Drying Time Chlorhexidine gluconate - Drying Time | Completed | University of British Columbia | 20 | 2014-04-01 | 2017-08-07 |
Showing 20 of 30. Sign in to see all of them.
Surgical Wound Infection (13) · Infections (4) · Bacteremia (2) · Emergencies (1) · Endometritis (1) · Fractures, Open (1) · Hip Fractures (1)
Zurex Pharma, Inc. (8) · Solventum US LLC (4) · 3M (1) · Baylor College of Medicine (1) · Becton, Dickinson and Company (1) · Brigham and Women's Hospital (1) · Gama Healthcare Ltd. (1) · Hyagriv Simhan (1) · Instituto de Investigacion Sanitaria La Fe (1) · Lakehead University (1) · National Institute of Allergy and Infectious Diseases (NIAID) (1) · Northwestern University (1) · Sanford Health (1) · Thammasat University (1) · Universidad de El Salvador (1)
United States (22) · Canada (2) · United Kingdom (2) · El Salvador (1) · Thailand (1)
Arvind Palanisamy, MD, FRCA (1) · Auchara Tangsathapornponng, MD (1) · Chris Beausoleil (1) · Daryl Bendel (1) · Erik S. Thingvoll, MD (1) · Esther Campbell (1) · Gary L Grove, PhD (1) · Gerard Slobogean, MD (1) · Jamie Miller, ADN (1) · Joseph P Hart, MD, FACS, DFSVS (1) · Kurt Droll, MD (1) · Kyle T Judd, MD (1) · M H Bashir, MD (1) · M. Hamid Bashir, MD (1) · Maggie Butler, PhD (1)
PMID 32131912, PMID 20054046, PMID 25322531, PMID 28277409, PMID 32259266, PMID 32787892, PMID 37002119, PMID 38294973