3 completed, 1 recruiting. 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 2 | Completed 1, Recruiting 1 |
Follow Bypassing Agents: new trials by email Literature Review of Bypassing Agents trials Research Report on Bypassing Agents
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Assess the Efficacy and Safety of Emicizumab in Participants With Type 3 Von Willebrand Disease Emicizumab, von Willebrand Factor (VWF) Concentrates, Factor VIII (FVIII) Concentrates - Von Willebrand Disease, Type 3 | Phase 3 | Recruiting | Hoffmann-La Roche | 75 | 2025-06-27 | 2026-11-12 |
| Clinical Outcomes Between Pulsatile and Non-Pulsatile Flow During Cardiopulmonary Bypass Bypassing Agents - Cardiac Surgery, Cardiac Surgery Requiring Cardiopulmonary Bypass | Completed | Tribhuvan University Teaching Hospital, Institute Of Medicine. | 80 | 2019-07-23 | 2025-06-08 | |
| A Study of Fitusiran (ALN-AT3SC) in Severe Hemophilia A and B Patients With Inhibitors fitusiran, Bypassing agents - Hemophilia A, Hemophilia B | Phase 3 | Completed | Genzyme, a Sanofi Company | 60 | 2018-02-14 | 2022-03-28 |
| A Prospective Study to Collect High-Quality Documentation of Bleeds, Health-Related Quality of Life (HRQoL), and Safety Outcomes in Patients With Hemophilia A Treated With Standard-of-Care Treatment Bypassing Agents, FVIII Replacement - Hemophilia A | Completed | Hoffmann-La Roche | 221 | 2015-05-26 | 2017-05-30 |
Hemophilia A (2) · Blood Coagulation Disorders (1) · Blood Coagulation Disorders, Inherited (1) · Coagulation Protein Disorders (1) · Genetic Diseases, Inborn (1) · Genetic Diseases, X-Linked (1) · Hematologic Diseases (1) · Hemophilia B (1) · Hemorrhagic Disorders (1) · von Willebrand Disease, Type 3 (1)
Hoffmann-La Roche (2) · Genzyme, a Sanofi Company (1) · Tribhuvan University Teaching Hospital, Institute Of Medicine. (1)
Germany (3) · Italy (3) · Japan (3) · South Africa (3) · Spain (3) · United States (3) · Australia (2) · Canada (2) · China (2) · France (2) · Poland (2) · South Korea (2) · Taiwan (2) · United Kingdom (2) · Belgium (1)
PMID 32776489, PMID 34922648, PMID 35114155, PMID 37003287
2016 (1)