4 unknown, 2 completed, 1 not yet recruiting, 1 recruiting. 3 Not applicable, 3 Phase 2, 1 Early Phase 1, 1 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 3 | Completed 1, Recruiting 1, Withdrawn 1 |
| Phase 2 | 3 | Unknown 2, Completed 1 |
| Early Phase 1 | 1 | Unknown 1 |
| Phase 1 | 1 | Unknown 1 |
| Phase 3 | 1 | Not yet recruiting 1 |
| Phase 4 | 1 | Unknown 1 |
Follow Bromelain: new trials by email Literature Review of Bromelain trials Research Report on Bromelain
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Bromelain for Post-surgery Facial Swelling Bromelain - Malocclusion | Not applicable | Recruiting | Mohamed Bazina | 200 | 2025-09-08 | 2026-06-05 |
| The Effects of Bromelain Supplement in Patients with Diabetic Foot Ulcers Bromelain, Placebo - Diabetic Foot Ulcer (DFU) | Phase 3 | Not yet recruiting | Dr Azita Hekmatdoost | 70 | 2025-03-01 | 2025-01-22 |
| Oral Bromelain After Bilateral Mandibular Third Molar Surgery Bromelain, Standard postoperative medication - Impacted Third Molar Tooth, Postoperative Pain Control | Not applicable | Completed | Istanbul Kent University | 40 | 2024-06-16 | 2026-10-26 |
| Effect of Bromelain Versus Calcium Hydroxide as an Intracanal Medication on the Intensity of Postoperative Pain and Bacterial Load Reduction in Necrotic Single Rooted Lower Premolars bromelain, Calcium hydroxide - Intracanal Medication, Bromelain | Early Phase 1 | Unknown | Cairo University | 30 | 2023-02-10 | 2023-01-18 |
| BromAc for Recurrent Peritoneal Mucinous Tumour or Pseudomyxoma Peritonei Bromelain, Acetylcysteine, Interventional radiology insertion of drain - Pseudomyxoma Peritonei, Peritoneal Cancer | Phase 2 | Unknown | Mucpharm Pty Ltd | 62 | 2022-05-01 | 2022-03-15 |
| Safety of Nebulized Combination Therapy BromAc® in COVID-19 Respiratory Disease Bromelains, Acetylcysteine - COVID-19 Pneumonia, COVID-19 | Phase 1 / Phase 2 | Unknown | Mucpharm Pty Ltd | 30 | 2022-05-01 | 2022-02-28 |
| The Study of Quadruple Therapy Zinc, Quercetin, Bromelain and Vitamin C on the Clinical Outcomes of Patients Infected With COVID-19 Quercetin, bromelain, Zinc - Covid-19 | Phase 4 | Unknown | Ministry of Health, Saudi Arabia | 60 | 2020-06-20 | 2020-07-13 |
| Arnica Montana and Bromelain in Rhinoplasty Arnica Montana, Bromelain, Placebo - Wound Healing | Not applicable | Withdrawn | Boston Medical Center | 2019-08-01 | 2019-08-15 | |
| Evaluation of Oral Plaque Removal Utilizing an Adjunct Enzyme Pre-rinse Bromelain, Powdered sugar - Dental Plaque, Dental Caries | Phase 2 | Completed | Indiana University | 46 | 2018-06-14 | 2020-12-03 |
COVID-19 (2) · Adenocarcinoma, Mucinous (1) · Dental Caries (1) · Dental Plaque (1) · Diabetic Foot (1) · Malocclusion (1) · Neoplasms, Cystic, Mucinous, and Serous (1) · Pneumonia, Ventilator-Associated (1) · Pseudomyxoma Peritonei (1) · Trismus (1)
Mucpharm Pty Ltd (2) · Boston Medical Center (1) · Cairo University (1) · Dr Azita Hekmatdoost (1) · Indiana University (1) · Istanbul Kent University (1) · Ministry of Health, Saudi Arabia (1) · Mohamed Bazina (1)
United States (3) · Iran (1) · Saudi Arabia (1) · Turkey (Türkiye) (1)
Alvaro Arjona Sanchez, MD (1) · Armando Sardi, MD (1) · Edward Levine, MD (1) · Frank MP van Haren, MD, PhD (1) · Haroon Choudry, MD (1) · Ignace de Hingh, MD (1) · Jacqueline Wulu, MD (1) · Kamyab Andarzbakhsh, PharmD (1) · Kelton Stewart, DDS, MS (1) · Mobina Tajdari, PharmD Student (1) · Mohamed Bazina, DDS, MSD (1)