51 completed, 7 unknown, 6 terminated, 2 withdrawn. 44 Phase 2, 18 Phase 3, 9 Phase 1, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 44 | Completed 39, Terminated 3, Unknown 1, Withdrawn 1 |
| Phase 3 | 18 | Completed 11, Unknown 6, Terminated 1 |
| Phase 1 | 9 | Completed 6, Terminated 2, Withdrawn 1 |
| Phase 4 | 1 | Completed 1 |
Follow bone marrow ablation with stem cell support: new trials by email Literature Review of bone marrow ablation with stem cell support trials Research Report on bone marrow ablation with stem cell support
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Melphalan and Amifostine Followed By One or Two Autologous or Syngeneic Stem Cell Transplants and Maintenance Therapy in Treating Patients With Stage II-III Multiple Myeloma melphalan, amifostine trihydrate, peripheral blood stem cell transplantation - Refractory Multiple Myeloma, Stage II Multiple Myeloma | Phase 3 | Completed | Fred Hutchinson Cancer Center | 130 | 2005-07-01 | 2015-08-21 |
| Combination Chemotherapy With or Without Trastuzumab Followed By an Autologous Stem Cell Transplant and Radiation Therapy in Treating Patients With Stage III or Stage IV Breast Cancer trastuzumab, carboplatin, cyclophosphamide - Breast Cancer | Phase 2 | Completed | City of Hope Medical Center | 32 | 2005-07-01 | 2017-02-23 |
| Busulfan, Melphalan, and Thiotepa in Treating Patients Who Are Undergoing an Autologous Stem Cell Transplant for Hodgkin's or Non-Hodgkin's Lymphoma filgrastim, busulfan, melphalan - Lymphoma | Phase 2 | Completed | OHSU Knight Cancer Institute | 37 | 2005-03-01 | 2017-09-27 |
| Rituximab, Cyclophosphamide, and G-CSF Followed By Combination Chemotherapy in Treating Patients Who Are Undergoing Autologous Stem Cell Transplant Followed By Rituximab and GM-CSF for Refractory Diffuse Large B-Cell Lymphoma filgrastim, rituximab, sargramostim - Lymphoma | Phase 2 | Completed | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 44 | 2004-03-01 | 2017-09-28 |
| Amifostine and Melphalan in Treating Patients With Primary Systemic Amyloidosis Who Are Undergoing Peripheral Stem Cell Transplantation filgrastim, amifostine trihydrate, melphalan - Drug/Agent Toxicity by Tissue/Organ, Multiple Myeloma and Plasma Cell Neoplasm | Phase 1 | Terminated | Eastern Cooperative Oncology Group | 8 | 2004-01-22 | 2023-06-18 |
| Immunotherapy Using Cyclosporine, Interferon Gamma, and Interleukin-2 After High-Dose Myeloablative Chemotherapy With Autologous Stem Cell Transplantation in Treating Patients With Refractory or Relapsed Hodgkin's Lymphoma aldesleukin, filgrastim, recombinant interferon gamma - Lymphoma | Phase 2 / Phase 3 | Completed | Children's Oncology Group | 24 | 2003-11-01 | 2013-10-17 |
| Donor White Blood Cell Infusions and Interleukin-2 in Treating Patients Who Are Undergoing an Autologous Stem Cell Transplant for Relapsed Advanced Lymphoid Cancer aldesleukin, therapeutic allogeneic lymphocytes, melphalan - Graft Versus Host Disease, Leukemia | Phase 1 / Phase 2 | Completed | Fred Hutchinson Cancer Center | 20 | 2003-08-01 | 2010-09-21 |
| Chemotherapy and Stem Cell Transplantation in Treating Children With Central Nervous System Cancer filgrastim, carboplatin, etoposide - Brain and Central Nervous System Tumors, Lymphoma | Phase 1 | Completed | Roswell Park Cancer Institute | 1 | 2002-03-01 | 2011-03-01 |
| Combination Chemotherapy With or Without Filgrastim Before Surgery, High-Dose Chemotherapy, and Radiation Therapy Followed by Isotretinoin With or Without Monoclonal Antibody in Treating Patients With Neuroblastoma filgrastim, monoclonal antibody Ch14.18, busulfan - Neuroblastoma | Phase 3 | Unknown | University of Leicester | 175 | 2001-12-01 | 2014-06-24 |
| Chemotherapy and Peripheral Stem Cell Transplantation Followed By Immunotherapy in Treating Patients With Multiple Myeloma filgrastim, pneumococcal polyvalent vaccine, therapeutic autologous lymphocytes - Infection, Multiple Myeloma and Plasma Cell Neoplasm | Phase 1 / Phase 2 | Completed | University of Maryland, Baltimore | 2001-12-01 | 2019-11-04 | |
| Combination Chemotherapy, Peripheral Stem Cell Transplantation, and Biological Therapy in Treating Patients With Solid Tumors or Lymphoma aldesleukin, filgrastim, sargramostim - Lymphoma, Unspecified Adult Solid Tumor, Protocol Specific | Phase 2 | Completed | Fred Hutchinson Cancer Center | 2001-08-01 | 2010-05-14 | |
| Combination Chemotherapy and Peripheral Stem Cell Transplant in Treating Patients With Relapsed Hodgkin's Lymphoma filgrastim, carmustine, cisplatin - Lymphoma | Phase 3 | Unknown | German Hodgkin's Lymphoma Study Group | 220 | 2001-07-01 | 2013-09-17 |
| Combination Chemotherapy With or Without Thalidomide in Treating Patients With Multiple Myeloma filgrastim, recombinant interferon alfa, cyclophosphamide - Multiple Myeloma and Plasma Cell Neoplasm | Phase 3 | Unknown | Commissie Voor Klinisch Toegepast Onderzoek | 450 | 2001-03-01 | 2013-09-17 |
| Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Neuroblastoma filgrastim, carboplatin, cisplatin - Neuroblastoma | Phase 3 | Completed | Children's Oncology Group | 495 | 2001-02-01 | 2013-05-17 |
| Chemotherapy, Surgery, Radiation Therapy and Bone Marrow or Peripheral Stem Cell Transplantation in Treating Patients With Primary CNS Germ Cell Tumors filgrastim, carboplatin, cyclophosphamide - Brain and Central Nervous System Tumors | Phase 2 | Unknown | Children's Hospital Los Angeles | 2000-12-01 | 2013-12-18 | |
| Chemotherapy Followed by Radiation Therapy and Peripheral Stem Cell Transplant Compared With Chemotherapy Plus Interferon Alfa in Treating Patients With Stage III or Stage IV Mantle Cell Lymphoma filgrastim, recombinant interferon alfa, carmustine - Lymphoma | Phase 3 | Unknown | German Low Grade Lymphoma Study Group | 2000-12-01 | 2013-09-17 | |
| Chemotherapy and Peripheral Stem Cell Transplant With or Without Monoclonal Antibody Therapy in Treating Patients With Non-Hodgkin's Lymphoma filgrastim, rituximab, carmustine - Lymphoma | Phase 3 | Completed | Commissie Voor Klinisch Toegepast Onderzoek | 340 | 2000-09-01 | 2013-08-12 |
| Filgrastim Compared With Sargramostim Plus Chemotherapy, Peripheral Stem Cell Transplantation, and Interferon Alfa in Treating Patients With Multiple Myeloma carmustine, cyclophosphamide, dexamethasone - Multiple Myeloma and Plasma Cell Neoplasm | Phase 2 | Terminated | Masonic Cancer Center, University of Minnesota | 87 | 2000-08-01 | 2017-11-29 |
| Multiple Therapies in Treating Patients With Advanced Neuroblastoma filgrastim, monoclonal antibody 3F8, sargramostim - Neuroblastoma | Phase 2 | Completed | Memorial Sloan Kettering Cancer Center | 2000-06-01 | 2013-03-07 | |
| Cyclophosphamide W/or W/Out Rituximab and Peripheral Stem Cell Transplantation in Patients With Recurrent Non-Hodgkin's Lymphoma filgrastim, rituximab, carmustine - Lymphoma | Phase 2 | Completed | Case Comprehensive Cancer Center | 37 | 2000-06-01 | 2010-06-10 |
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Lymphoma (29) · Lymphoma, Follicular (18) · Lymphoma, Large B-Cell, Diffuse (17) · Lymphoma, Large-Cell, Immunoblastic (15) · Lymphoma, Non-Hodgkin (15) · Multiple Myeloma (15) · Leukemia (14) · Neoplasms, Plasma Cell (14) · Burkitt Lymphoma (12) · Hodgkin Disease (12) · Leukemia, Lymphocytic, Chronic, B-Cell (12) · Lymphoma, Mantle-Cell (12) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (11) · Leukemia, Myeloid, Acute (9) · Lymphoma, B-Cell, Marginal Zone (9)
Memorial Sloan Kettering Cancer Center (6) · University of Maryland, Baltimore (6) · Children's Oncology Group (4) · Case Comprehensive Cancer Center (3) · City of Hope Medical Center (3) · EBMT Solid Tumors Working Party (3) · Eastern Cooperative Oncology Group (3) · Fred Hutchinson Cancer Center (3) · Herbert Irving Comprehensive Cancer Center (3) · Roswell Park Cancer Institute (3) · Temple University (3) · Commissie Voor Klinisch Toegepast Onderzoek (2) · European Organisation for Research and Treatment of Cancer - EORTC (2) · Northwestern University (2) · Cancer Treatment Centers of America (1)
United States (51) · Belgium (8) · Switzerland (8) · Austria (6) · Canada (6) · Germany (6) · Netherlands (6) · Australia (5) · Italy (5) · United Kingdom (5) · Denmark (4) · Spain (4) · France (3) · Poland (3) · Portugal (3)
Aaron P. Rapoport, MD (3) · Barry R. Meisenberg, MD (3) · Charles S. Hesdorffer, MD (3) · Kenneth F. Mangan, MD, FACP (3) · Barbara Jean Bambach, MD (2) · George Somlo, MD (2) · Morie A. Gertz, MD (2) · Patrick J. Stiff, MD (2) · Thomas C. Shea, MD (2) · Achiel Van Hoof, MD (1) · Alessandro Levis, MD (1) · Allen R. Chen, MD, PhD, MHS (1) · Andreas Engert, MD (1) · Anton Hagenbeek, MD, PhD (1) · Bipin N. Savani, MD (1)
PMID 15156165, PMID 16888080, PMID 17235042, PMID 17698804, PMID 17971487, PMID 18077791, PMID 18166796, PMID 18256325, PMID 18623206, PMID 19880501, PMID 20567002, PMID 21059637, PMID 21328522, PMID 22442350, PMID 22490331, PMID 22742881, PMID 23547078, PMID 23890779, PMID 24171516, PMID 24419114, PMID 24625415, PMID 28327958, PMID 7774830, PMID 9193322
P30CA033572 (3), P30CA043703 (3), U10CA032102 (2), P30CA006973 (1), P30CA008748 (1), P30CA069533 (1), U10CA021115 (1)