4 completed, 3 unknown, 1 recruiting, 1 terminated. 4 Phase 2, 2 Phase 3, 2 Phase 4, 1 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 4 | Completed 3, Unknown 1 |
| Phase 3 | 2 | Completed 1, Terminated 1 |
| Phase 4 | 2 | Completed 1, Recruiting 1 |
| Not applicable | 1 | Unknown 1 |
Follow beta-Lactams: new trials by email Literature Review of beta-Lactams trials Research Report on beta-Lactams
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Beta-lactam Plus Levofloxacin to Enhance Therapy in Streptococcal Septicemia Beta-lactam monotherapy, Beta-lactam plus levofloxacin combination therapy - Bacteremia, Streptococcus Infection | Phase 4 | Recruiting | Mahidol University | 165 | 2026-01-08 | 2026-08-21 |
| Combination Antibiotic Therapy Compared to Monotherapy in the Treatment of Acute COPD Beta-Lactams, Fluoroquinolone - COPD Exacerbation Acute | Phase 2 / Phase 3 | Completed | Haiphong University of Medicine and Pharmacy | 170 | 2020-01-01 | 2021-05-10 |
| Efficacy of Intravenous Fosfomycin in the Treatment of Complicated Urinary in Real-life Conditions. Drug: Intravenous fosfomycin, Drug: Intravenous quinolone or beta-lactam - Complicated Urinary Tract Infection | Unknown | Fundación Pública Andaluza para la gestión de la Investigación en Sevilla | 400 | 2019-10-21 | 2019-11-14 | |
| Combination Antibiotic Therapy for Methicillin Resistant Staphylococcus Aureus Infection Beta-Lactam - Methicillin-Resistant Staphylococcus Aureus | Phase 3 | Terminated | Menzies School of Health Research | 358 | 2015-08-26 | 2018-12-19 |
| Short Duration Treatment of Non-severe Community Acquired Pneumonia Chest X-ray, blood sampling /Cell Counts/ C reactive protein (CRP)/Biochemistry, Augmentin - Community Acquired Pneumonia | Phase 2 | Unknown | Versailles Hospital | 310 | 2013-11-01 | 2017-08-14 |
| Evaluation of Extended Intravenous of Beta-lactams in the Treatment of Serious Gram-negative Infections in Critically Ill Patients Beta-Lactams - Gram-Negative Bacterial Infections | Not applicable | Unknown | National Taiwan University Hospital | 100 | 2012-02-01 | 2012-05-17 |
| Monotherapy Versus Bitherapy in Non-severe Hospitalized Community-acquired Pneumonia Beta lactam (amoxicillin / clav. acid OR cefuroxime), Beta-lactam (amoxicillin / clav. acid OR cefuroxime) AND macrolide (clarithromycin) - Community-acquired Pneumonia | Phase 4 | Completed | Swiss National Fund for Scientific Research | 601 | 2009-01-01 | 2013-04-25 |
| A Study of Beta-Lactam in Hospitalized Patients With Skin and Skin Structure Infections Standard care, beta-lactam - Soft Tissue Infections | Phase 2 | Completed | Hoffmann-La Roche | 313 | 2005-12-01 | 2016-11-02 |
| A Study to Assess Beta-Lactam in the Treatment of Hospitalized Patients With Bacterial Pneumonia Ceftriaxone, beta-lactam - Pneumonia, Bacterial | Phase 2 | Completed | Hoffmann-La Roche | 302 | 2005-03-01 | 2016-11-02 |
Community-Acquired Pneumonia (2) · Bacteremia (1) · Community-Acquired Infections (1) · Escherichia coli Infections (1) · Gram-Negative Bacterial Infections (1) · Pneumonia (1) · Pneumonia, Bacterial (1) · Soft Tissue Infections (1) · Streptococcal Infections (1)
Hoffmann-La Roche (2) · Fundación Pública Andaluza para la gestión de la Investigación en Sevilla (1) · Haiphong University of Medicine and Pharmacy (1) · Mahidol University (1) · Menzies School of Health Research (1) · National Taiwan University Hospital (1) · Swiss National Fund for Scientific Research (1) · Versailles Hospital (1)
Argentina (2) · Bulgaria (2) · Hungary (2) · Latvia (2) · Lithuania (2) · Peru (2) · Romania (2) · United States (2) · Australia (1) · Chile (1) · Croatia (1) · Estonia (1) · France (1) · Germany (1) · Israel (1)
Arnaud Perrier, MD (1) · Jean-Emmanuel Kahn, Dr (1) · Joshua Davis, MBBS, FRACP (1)
PMID 25286173, PMID 27029920, PMID 32044943, PMID 33773631, PMID 35505308, PMID 38734138