8 completed, 3 terminated. 7 Phase 1, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 7 | Completed 6, Terminated 1 |
| Phase 2 | 4 | Completed 2, Terminated 2 |
Follow AZD1386: new trials by email Literature Review of AZD1386 trials Research Report on AZD1386
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Esophageal Hypersensitivity Study in Patients With Gastroesophageal Reflux Disease (GERD) AZD1386, Placebo to AZD1386 - Sensitivity in Esophagus | Phase 2 | Completed | AstraZeneca | 14 | 2009-11-01 | 2012-11-09 |
| Study to Evaluate Efficacy, Safety, Tolerability and Pharmacokinetics of AZD1386 in Patients With Peripheral Neuropathic Pain AZD1386, Placebo - Pain, Neuropathic Pain | Phase 2 | Terminated | AstraZeneca | 90 | 2009-09-01 | 2009-12-23 |
| Double-blind Placebo-controlled 2-part Study Assessing the Safety, Tolerability and PK of AZD1386 in Healthy Volunteers AZD1386, Placebo for AZD1386, Naproxen - Healthy Volunteers | Phase 1 | Terminated | AstraZeneca | 11 | 2009-08-01 | 2010-12-10 |
| Study to Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of AZD1386 in Patients With Osteoarthritis (OA) of the Knee AZD1386, Placebo - Pain | Phase 2 | Terminated | AstraZeneca | 241 | 2009-03-01 | 2012-06-04 |
| Investigation of Rate+Extent of Excretion of Radioactivity in Urine+Faeces After Oral Administration of [14C]AZD1386 AZD1386 - Pain | Phase 1 | Completed | AstraZeneca | 6 | 2009-01-01 | 2009-04-28 |
| Esophageal Hypersensitivity Study in Healthy Volunteers AZD1386, Placebo - Pain, Esophageal Sensitivity | Phase 1 | Completed | AstraZeneca | 45 | 2008-06-01 | 2009-08-28 |
| Formulation and Food Effect Study of AZD1386 in Healthy Volunteers AZD1386 - Pharmacokinetics | Phase 1 | Completed | AstraZeneca | 12 | 2008-06-01 | 2010-12-10 |
| AZD1386 Japanese Multiple Ascending Dosing Study AZD1386, Placebo - Chronic Pain | Phase 1 | Completed | AstraZeneca | 32 | 2008-06-01 | 2009-09-30 |
| Study to Investigate the Analgesic Efficacy of a Single Dose of AZD1386 AZD1386, Naproxen, Placebo - Pain | Phase 2 | Completed | AstraZeneca | 103 | 2008-04-01 | 2012-06-08 |
| Study to Investigate the Safety, Tolerability and Pharmacokinetics of AZD1386 AZD1386, Placebo - Chronic Pain | Phase 1 | Completed | AstraZeneca | 69 | 2008-02-01 | 2010-12-10 |
| Study to Investigate the Effects Single Oral Dose of AZD1386 (Capsaicin) AZD1386, Placebo - Capsaicin Evoked Pain, Heat Sensitivity | Phase 1 | Completed | AstraZeneca | 36 | 2008-01-01 | 2008-06-06 |
Pain (7) · Chronic Pain (2) · Gastroesophageal Reflux (2) · Neuralgia (1) · Neuralgia, Postherpetic (1)
AstraZeneca (11)
United Kingdom (4) · Denmark (3) · Canada (2) · Japan (2) · Sweden (2) · Bulgaria (1) · Finland (1) · France (1) · Hungary (1) · Poland (1) · Slovakia (1) · United States (1)
Marie Sundin (2) · Rolf Karlsten (2) · Agneta Berg (1) · Bror Jonzon (1) · Dr. Tania Hugo (1) · Klaus Francke, MD (1) · Lynn Webster, MD (1) · Ola Svensson, MD (1) · Peter Funch-Jensen, MD, PhD (1) · Peter Funch-Jensen,, MD, PhD (1) · Raj Chetty, MD (1) · Ray Chetty (1) · Richard L Leff, MD (1)
PMID 21410733, PMID 23320520, PMID 24394343
2008 (2)