20 completed, 2 recruiting, 2 unknown, 2 withdrawn. 8 Phase 2, 7 Phase 1, 4 Not applicable, 4 Phase 3, 3 Early Phase 1.
Follow Atropine Sulfate: new trials by email Literature Review of Atropine Sulfate trials Research Report on Atropine Sulfate
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Dexmedetomidine Infusion Dose Versus Rapid Bolus Dose Before Tracheal Intubation. Dexmedetomidine infusion, Dexmedetomidine bolus, Atropine Sulfate - Dexmedetomidine, Intubation Complication | Phase 2 | Completed | Kasr El Aini Hospital | 70 | 2024-04-01 | 2026-07-09 |
| Study of Atropine Sulfate Eye Drops(0.01%) in Treating Near-work-induced Transient Myopia in Children Atropine Sulfate, Placebo - Myopia | Phase 3 | Completed | Ocumension Therapeutics (Suzhou) Co., Ltd | 148 | 2023-06-25 | 2024-11-20 |
| A Study of Atropine Sulfate in Healthy Chinese Volunteers Atropine sulfate eye drops - Pharmacokinetics | Phase 1 | Unknown | Zhaoke (Hong Kong) Ophthalmology Pharmaceutical Limited | 30 | 2023-05-09 | 2023-05-11 |
| Safety and Tolerability Evaluation of PRO-230 Ophthalmic Solution Atropine Sulfate - Myopia | Phase 1 | Withdrawn | Laboratorios Sophia S.A de C.V. | 2023-02-01 | 2024-07-01 | |
| Phase I Clinical Trial to Evaluate the Safety and Tolerability of Ophtalmic Solution PRO-201 Atropine Sulfate - Myopia | Phase 1 | Completed | Laboratorios Sophia S.A de C.V. | 29 | 2022-08-20 | 2026-02-05 |
| Dropless Pars Plana Vitrectomy Study Pars plana vitrectomy, Triamcinolone Acetonide 40mg/mL, Moxifloxacin 0.5% or Polymyxin/Trimethoprim if patient is allergic to moxifloxacin - Rhegmatogenous Retinal Detachment | Phase 4 | Completed | Massachusetts Eye and Ear Infirmary | 168 | 2022-07-25 | 2026-09-18 |
| Safety, Tolerability and Pharmacodynamics Evaluation of CBT-009 Eye Drop CBT-009, Vehicle, Atropine Sulfate - Myopia, Progressive | Phase 1 / Phase 2 | Completed | Cloudbreak Therapeutics, LLC | 84 | 2022-07-20 | 2023-01-27 |
| The Personalized Chinese Herb Formulas Over Hypertensive Bradyarrhythmia Safflower (Carthamus Tinctorius) IgG4 | Serum | Allergy, Atropine Sulfate - Hypertensive Heart Disease | Not applicable | Completed | Jun Xiao | 72 | 2020-01-20 | 2020-08-10 |
| Intrathecal Atropine vs IV Metoclopramide for Nausea & Vomiting During CS Atropine sulfate, Metoclopramide - Nausea, Vomiting | Phase 4 | Completed | Mansoura University | 60 | 2019-05-05 | 2019-10-07 |
| The Safety and Efficacy of SYD-101 in Children With Myopia SYD-101 0.01%, SYD-101 0.03%, Vehicle - Nearsightedness, Near Sightedness | Phase 3 | Completed | Sydnexis, Inc. | 852 | 2019-04-24 | 2026-07-30 |
| Role of Acetylcholine in Blood Flow Regulation in Healthy Adults: Effects of Age and Exercise Training Handgrip Exercise Training, Acetylcholine, Adenosine Triphosphate - Vasoconstriction, Vasodilation | Early Phase 1 | Withdrawn | Colorado State University | 2019-04-16 | 2021-08-02 | |
| Low-dose Atropine Eye Drops to Reduce Progression of Myopia in Children in the United Kingdom Atropine Sulfate, Placebo - Myopia | Phase 2 | Active not recruiting | Belfast Health and Social Care Trust | 289 | 2019-04-03 | 2023-09-07 |
| Side Effects of Atropine (SEA) Study 0.01% concentration atropine drops - Myopia | Phase 1 / Phase 2 | Completed | Jeffrey J. Walline, OD PhD | 31 | 2018-07-23 | 2022-12-02 |
| Adverse Events Related to Low Dose Atropine Atropine Sulfate - Myopia, Progressive | Completed | Scripps Health | 148 | 2018-06-19 | 2023-04-25 | |
| E7 TCR T Cells for Human Papillomavirus-Associated Cancers E7 TCR cells, Aldesleukin, Fludarabine - Papillomavirus Infections, Cervical Intraepithelial Neoplasia | Phase 1 / Phase 2 | Completed | National Cancer Institute (NCI) | 224 | 2017-01-27 | 2026-03-09 |
| The Impact of Intravenous Anaesthesia on Angiogenesis in Patients With Breast Cancer (TIVA/TCI-BC) Lidocaine, Sevoflurane, TIVA-TCI - Breast Cancer | Phase 2 | Completed | Iuliu Hatieganu University of Medicine and Pharmacy | 120 | 2016-08-01 | 2019-10-29 |
| The Effects of Bariatric Surgeries on Glucose Metabolism Exendin-(9-39), Atropine - Post Bariatric Surgery, Gastric Bypass | Early Phase 1 | Recruiting | The University of Texas Health Science Center at San Antonio | 200 | 2015-07-01 | 2025-09-09 |
| StahistRx Phase 2, Five-arm, Parallel Group, Active vs Active, Double-blind Study PSE 120 mg, CM 8 mg, Atr 0.36 mg, PSE 120 mg, CM 8 mg, Atr 0.24 mg, PSE 120 mg, CM 8 mg, Atr 0.12 mg - Rhinitis, Seasonal, Allergic | Phase 2 | Unknown | Magna Pharmaceuticals, Inc. | 125 | 2014-03-01 | 2014-05-30 |
| Heart Rate Response to Atropine Doses Less Than 0.1mg IV to Anesthetized Infants Atropine - Bradycardia, Arrhythmias | Phase 4 | Completed | State University of New York at Buffalo | 60 | 2013-02-01 | 2023-04-06 |
| Intubation Time With Low Dose Rocuronium Atropine, Normal saline - Intubation; Difficult | Not applicable | Completed | Gachon University Gil Medical Center | 44 | 2011-05-01 | 2011-11-03 |
Showing 20 of 27. Sign in to see all of them.
Myopia (7) · Hypoglycemia (2) · Myopia, Degenerative (2) · Aneurysm (1) · Arrhythmias, Cardiac (1) · Bradycardia (1) · Breast Neoplasms (1) · Carcinoma in Situ (1) · Heart Arrest (1) · Inflammation (1) · Motor Activity (1) · Nausea (1) · Organophosphate Poisoning (1) · Papillomavirus Infections (1) · Photophobia (1)
Laboratorios Sophia S.A de C.V. (2) · The University of Texas Health Science Center at San Antonio (2) · Baskent University (1) · Belfast Health and Social Care Trust (1) · Cloudbreak Therapeutics, LLC (1) · Colorado State University (1) · Craig J. Huang (1) · Gachon University Gil Medical Center (1) · Iuliu Hatieganu University of Medicine and Pharmacy (1) · Jeffrey J. Walline, OD PhD (1) · Jun Xiao (1) · Kasr El Aini Hospital (1) · Magna Pharmaceuticals, Inc. (1) · Mansoura University (1) · Massachusetts Eye and Ear Infirmary (1)
United States (13) · China (3) · Egypt (2) · Australia (1) · Austria (1) · Mexico (1) · Norway (1) · Romania (1) · Slovakia (1) · South Korea (1) · Turkey (Türkiye) (1) · United Kingdom (1)
Marzieh Salehi, MD, MS (2) · Adriana Rodriguez, MD (1) · Anand Chockalingam, MD (1) · Anis Aribogan, Prof., MD (1) · Augusto Azuara-Blanco, PhD FRCOphth (1) · Craig Huang, MD (1) · Frank Dinenno, PhD (1) · Gregory Ostrow, MD (1) · Jeffrey Walline (1) · Jerrold Lerman, MD FRCPC (1) · Jong Yeop Kim, MD,PhD (1) · Lars Wik, MD, PhD (1) · Li Li (1) · Michael Donahoe, M.D. (1)
PMID 19934423, PMID 22698066, PMID 24247230, PMID 24465046, PMID 25762533, PMID 25794212, PMID 31653669, PMID 32616309, PMID 33558725, PMID 41870844, PMID 42276557
2017 (1), R01DK105379 (1)