9 completed, 2 terminated, 2 unknown. 5 Phase 3, 3 Not applicable, 3 Phase 2, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 5 | Completed 2, Terminated 2, Unknown 1 |
| Not applicable | 3 | Completed 2, Unknown 1 |
| Phase 2 | 3 | Completed 3 |
| Phase 1 | 2 | Completed 2 |
Follow Andrographis paniculata extract: new trials by email Literature Review of Andrographis paniculata extract trials Research Report on Andrographis paniculata extract
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Comparison of the Effectiveness of Sambiloto Herbs (Andrographis Paniculata) and Brisk Walking Exercise on Blood Pressure of Obese Patients Andrographis paniculata, Brisk Walking Exercise, Combination - MeSH | Not applicable | Unknown | Universitas Palangka Raya | 30 | 2024-07-21 | 2024-07-25 |
| Andrographis Paniculata vs Boesenbergia Rotunda vs Control in Asymptomatic COVID-19 Andrographis Paniculata, Boesenbergia, Standard supportive treatment - Covid19 | Phase 3 | Unknown | Mahidol University | 3060 | 2021-08-30 | 2021-09-09 |
| To Compare the Efficacy and Tolerability of A. Paniculata/A. Chilensis in Individuals With URTI A. Paniculata, A. Chilensis, A. Paniculata and A. Chilensis - Upper Respiratory Tract Infection | Phase 3 | Completed | Vedic Lifesciences Pvt. Ltd. | 225 | 2021-03-20 | 2022-05-10 |
| To Assess the Effect of 336 Days Exposure of Paractin® on Pain & Disease Progression in Patients Suffering From Osteoarthritis of Knee Joint. Andrographis paniculata [150 mg], Microcrystalline Cellulose (MCC) - Knee Osteoarthritis (Knee OA) | Not applicable | Completed | Vedic Lifesciences Pvt. Ltd. | 80 | 2021-03-13 | 2025-05-31 |
| Effects of an Adaptogenic Extract on Electrical Activity of the Brain in Elderly Subjects With Cognitive Impairment Andrographis and Withania, Placebo - Cognitive Impairment, Mild | Phase 1 | Completed | EuroPharma, Inc. | 16 | 2019-04-01 | 2019-11-14 |
| Magnesium, Vitamin B2, Feverfew, Andrographis Paniculata and Coenzyme Q10 for Episodic Migraine Prophylaxis magnesium, vitamin B2, feverfew, andrographis paniculata and coenzyme Q10 - Migraine | Completed | Corfu Headache Clinic | 113 | 2018-04-01 | 2020-07-09 | |
| The Effect of Andrographis Paniculata (AP) on Palliative Management of Advanced Esophageal Cancer Andrographis Paniculata - Squamous Cell Carcinoma of Esophagus | Phase 3 | Completed | Chinese University of Hong Kong | 30 | 2018-03-01 | 2021-11-08 |
| Assessment of the Efficacy of Andrographis Paniculata in Subjects With Mild to Moderate Osteoarthritis Placebo, Andrographis Paniculata - Knee Osteoarthritis | Not applicable | Completed | Vedic Lifesciences Pvt. Ltd. | 108 | 2017-12-13 | 2021-07-15 |
| HMPL-004 Maintenance Treatment in Subjects With Mild to Moderate Ulcerative Colitis HMPL-004, Placebo - Ulcerative Colitis | Phase 3 | Terminated | Hutchison Medipharma Limited | 66 | 2013-06-01 | 2020-01-13 |
| A Phase III Trial of HMPL-004 in Patients With Mild to Moderate Active Ulcerative Colitis HMPL-004 1800 mg/day, Placebo, HMPL-004 2400 mg/day - Ulcerative Colitis | Phase 3 | Terminated | Hutchison Medipharma Limited | 201 | 2013-03-01 | 2020-01-02 |
| Efficacy Study of Andrographis Paniculata Purified Standardized Extract (ApE) in Patients With Multiple Sclerosis (MS) 1 - Andrographis paniculata p/st extract, 2 - Excipients - Multiple Sclerosis, Relapsing-Remitting | Phase 1 / Phase 2 | Completed | Universidad Austral de Chile | 30 | 2012-01-01 | 2016-06-23 |
| Phase II Study of HMPL-004 in Patients With Ulcerative Colitis HMPL-004 low dose, Placebo, HMPL-004 high dose - Ulcerative Colitis | Phase 2 | Completed | Hutchison Medipharma Limited | 224 | 2008-02-07 | 2020-07-22 |
| Phase II Study of HMPL-004 in Subjects With Crohn's Disease HMPL-004, Placebo - Crohn's Disease | Phase 2 | Completed | Hutchison Medipharma Limited | 101 | 2006-04-01 | 2020-01-02 |
Colitis, Ulcerative (3) · Osteoarthritis, Knee (2) · COVID-19 (1) · Cognitive Dysfunction (1) · Crohn Disease (1) · Esophageal Squamous Cell Carcinoma (1) · Lymphoma, Follicular (1) · Migraine Disorders (1) · Motor Activity (1) · Multiple Sclerosis, Relapsing-Remitting (1) · Nervous System Diseases (1) · Obesity (1) · Respiratory Tract Infections (1)
Hutchison Medipharma Limited (4) · Vedic Lifesciences Pvt. Ltd. (3) · Chinese University of Hong Kong (1) · Corfu Headache Clinic (1) · EuroPharma, Inc. (1) · Mahidol University (1) · Universidad Austral de Chile (1) · Universitas Palangka Raya (1)
India (3) · United States (2) · Chile (1) · China (1) · Germany (1) · Greece (1) · Indonesia (1) · Thailand (1)
Rongjun Liu, MD (2) · Juan L. Hancke, PhD (1) · Klaus Koch, MD (1) · Liu Rongjun, Dr. (1) · Michail Michail, MD, MSc, PhD (1) · Philip WY Chiu, MD (1) · Shalini Srivastava, MD (1)