4 completed, 1 recruiting, 1 unknown, 1 withdrawn. 2 Phase 4, 1 Phase 1, 1 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 2 | Completed 2 |
| Phase 1 | 1 | Completed 1 |
| Phase 2 | 1 | Completed 1 |
| Phase 3 | 1 | Unknown 1 |
Follow X-linked Hypophosphatemia (XLH): new trials by email Literature Review of X-linked Hypophosphatemia (XLH) trials Research Report on X-linked Hypophosphatemia (XLH)
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Treatment Patterns, Biochemical Profiles and Clinical Outcomes in Adults With X-Linked Hypophosphatemia No treatment given - X-linked Hypophosphatemia (XLH) | Withdrawn | Novo Nordisk A/S | 2026-07-07 | 2026-08-28 | ||
| Effective Dosing of Burosumab in XLH X-linked Hypophosphatemia (XLH) | Recruiting | University of Nottingham | 120 | 2025-11-03 | 2026-05-11 | |
| Study to Assess the Safety, Pharmacokinetics and Efficacy of KRN23 in Pediatric Chinese Patients With XLH KRN23 - X-linked Hypophosphatemia (XLH) | Phase 4 | Completed | Kyowa Kirin Co., Ltd. | 28 | 2021-11-01 | 2024-07-09 |
| Study to Assess the Safety, Pharmacokinetics and Efficacy of KRN23 in Adult Chinese Patients With XLH KRN23 - X-linked Hypophosphatemia (XLH) | Phase 4 | Completed | Kyowa Kirin Co., Ltd. | 18 | 2021-09-28 | 2024-07-09 |
| Prevention of Spontaneous Dental Abscesses in Children With X-linked Hypophosphatemia : a RCT adhesive system, fluoride varnish, flowable composite - X-linked Hypophosphatemia (XLH) | Phase 3 | Unknown | Assistance Publique - Hôpitaux de Paris | 60 | 2021-06-01 | 2021-05-05 |
| Study to Assess the Safety, Tolerability, Pharmacokinetics and Efficacy of Burosumab in Patients Less Than 1 Year of Age Burosumab - X-linked Hypophosphatemia (XLH) | Phase 1 / Phase 2 | Completed | Kyowa Kirin Pharmaceutical Development Ltd | 16 | 2020-02-26 | 2024-11-07 |
| Retrospective and Prospective Disease Progression and Quality of Life in XLH None - Observational study - X-linked Hypophosphatemia (XLH) | Completed | Medialis Ltd. | 11 | 2019-07-07 | 2023-10-23 |
Familial Hypophosphatemic Rickets (7) · Bone Diseases, Metabolic (1) · Hypophosphatemia (1) · Nephrocalcinosis (1) · Rickets (1)
Avitaminosis (7) · Bone Diseases (7) · Calcium Metabolism Disorders (7) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (7) · Deficiency Diseases (7) · Female Urogenital Diseases (7) · Female Urogenital Diseases and Pregnancy Complications (7) · Genetic Diseases, Inborn (7) · Hypophosphatemia, Familial (7) · Kidney Diseases (7) · Male Urogenital Diseases (7) · Malnutrition (7) · Metabolic Diseases (7) · Metabolism, Inborn Errors (7) · Metal Metabolism, Inborn Errors (7)
burosumab (3) · flowable hybrid composite (1)
Kyowa Kirin Co., Ltd. (2) · Assistance Publique - Hôpitaux de Paris (1) · Kyowa Kirin Pharmaceutical Development Ltd (1) · Medialis Ltd. (1) · Novo Nordisk A/S (1) · University of Nottingham (1)
United Kingdom (3) · China (2) · France (2) · Italy (2) · Australia (1) · Austria (1) · Canada (1) · Germany (1) · Japan (1) · Netherlands (1) · Spain (1) · Sweden (1) · United States (1)
James Law, BMBS, PhD, MRCPCH (1)