4 completed, 2 recruiting. 6 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 6 | Completed 4, Recruiting 2 |
Follow Urea Cycle Disorders: new trials by email Literature Review of Urea Cycle Disorders trials Research Report on Urea Cycle Disorders
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| At Home Ammonia Monitoring of Inborn Errors of Ammonia Metabolism Ammonia Study Device - Urea Cycle Disorders, Organic Acidemias | Not applicable | Recruiting | Sequitur Health Corp. | 30 | 2025-09-23 | 2026-05-27 |
| Ureagenesis Analysis in Healthy Subjects and in Urea Cycle Disorder Patients Urea cycle flux study - Urea Cycle Disorders | Not applicable | Recruiting | University Children's Hospital, Zurich | 100 | 2019-10-31 | 2026-01-08 |
| Clinical Food Study to Evaluate the Effect of KB195 on Gut Nitrogen Metabolism in Patients With Urea Cycle Disorders KB195 (a novel mixture of oligosaccharides) - Urea Cycle Disorders | Not applicable | Completed | Kaleido Biosciences | 4 | 2019-01-06 | 2020-01-10 |
| Nitric Oxide Supplementation in Argininosuccinic Aciduria Nitric oxide supplement, Placebo - Argininosuccinic Aciduria, Argininosuccinate Lyase Deficiency | Not applicable | Completed | Baylor College of Medicine | 12 | 2014-09-01 | 2020-01-18 |
| Study in Healthy Subjects, Patients With Urea Cycle Disorders (UCD) and Carriers of UCD Mutations to Evaluate Urea Cycle Function oral administration of Sodium [1,2-13C]-Acetate - Urea Cycle Disorders | Not applicable | Completed | Cytonet GmbH & Co. KG | 37 | 2012-01-01 | 2013-06-26 |
| Study to Evaluate 13 C Isotope Ratio Measurement for Urea Cycle Capacity Assessment sodium [1-13C] acetate - Urea Cycle Disorders | Not applicable | Completed | Cytonet GmbH & Co. KG | 10 | 2009-09-01 | 2010-01-15 |
Urea Cycle Disorders, Inborn (6) · Argininosuccinic Aciduria (1) · Metabolic Diseases (1)
Amino Acid Metabolism, Inborn Errors (6) · Brain Diseases (6) · Brain Diseases, Metabolic (6) · Brain Diseases, Metabolic, Inborn (6) · Central Nervous System Diseases (6) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (6) · Genetic Diseases, Inborn (6) · Metabolism, Inborn Errors (6) · Nervous System Diseases (6) · Nutritional and Metabolic Diseases (6) · Metabolic Diseases (5)
Cytonet GmbH & Co. KG (2) · Baylor College of Medicine (1) · Kaleido Biosciences (1) · Sequitur Health Corp. (1) · University Children's Hospital, Zurich (1)
Germany (2) · Switzerland (2) · United States (2)
Doris Neuenhofer, MD (1) · Georg F Hoffmann, Prof Dr med (1) · Leslie F. Thomas, M.D. (1) · Mark Wingertzahn (1) · Marylaura L Thomas, Ph.D. (1) · Sandesh CS Nagamani, MD, FACMG (1)
R44HD112243 (1)