4 completed. 4 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 4 | Completed 4 |
Follow Tuberous Sclerosis Complex: new trials by email Literature Review of Tuberous Sclerosis Complex trials Research Report on Tuberous Sclerosis Complex
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Clinical Study of NPC-12Y Gel in Patients With Skin Lesions Associated With TSC NPC-12Y gel, NPC-12Y placebo gel - Tuberous Sclerosis Complex | Phase 3 | Completed | Nobelpharma | 43 | 2022-06-01 | 2024-11-22 |
| Adjunctive GNX Treatment Compared With Placebo in Children and Adults With TSC-related Epilepsy Ganaxolone, Placebo - Tuberous Sclerosis Complex | Phase 3 | Completed | Marinus Pharmaceuticals | 129 | 2022-04-01 | 2025-07-11 |
| An Open-label Extension Trial of Cannabidiol (GWP42003-P, CBD) for Seizures in Tuberous Sclerosis Complex (GWPCARE6) GWP42003-P - Tuberous Sclerosis Complex, Seizures | Phase 3 | Completed | Jazz Pharmaceuticals | 199 | 2016-08-31 | 2022-07-14 |
| A Randomized Controlled Trial of Cannabidiol (GWP42003-P, CBD) for Seizures in Tuberous Sclerosis Complex (GWPCARE6) GWP42003-P, Placebo - Tuberous Sclerosis Complex, Seizures | Phase 3 | Completed | Jazz Pharmaceuticals | 224 | 2016-04-06 | 2022-09-28 |
Tuberous Sclerosis (4) · Seizures (2)
Congenital Abnormalities (4) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (4) · Genetic Diseases, Inborn (4) · Hamartoma (4) · Heredodegenerative Disorders, Nervous System (4) · Malformations of Cortical Development (4) · Malformations of Cortical Development, Group I (4) · Neoplasms (4) · Neoplasms, Multiple Primary (4) · Neoplastic Syndromes, Hereditary (4) · Nervous System Diseases (4) · Nervous System Malformations (4) · Neurocutaneous Syndromes (4) · Neurodegenerative Diseases (4) · Neurologic Manifestations (2)
Cannabidiol (2) · ganaxolone (1)
Jazz Pharmaceuticals (2) · Marinus Pharmaceuticals (1) · Nobelpharma (1)
United States (3) · Australia (2) · Spain (2) · United Kingdom (2) · Canada (1) · China (1) · France (1) · Germany (1) · Israel (1) · Italy (1) · Japan (1) · Netherlands (1) · Poland (1)
PMID 34957550, PMID 33346789, PMID 35175622, PMID 38441854
2015 (2)