3 not yet recruiting, 2 withdrawn, 1 active not recruiting, 1 completed. 6 Phase 2, 2 Phase 3, 1 Early Phase 1, 1 Not applicable, 1 Phase 1.
Follow T Lymphoblastic Lymphoma: new trials by email Literature Review of T Lymphoblastic Lymphoma trials Research Report on T Lymphoblastic Lymphoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Testing the Addition of Daratumumab to Chemotherapy for Treating Patients With Newly-Diagnosed T-Cell Lymphoblastic Leukemia (T-ALL) and T-Cell Lymphoblastic Lymphoma (T-LL) Biopsy Procedure, Biospecimen Collection, Bone Marrow Aspiration - Stage II T Lymphoblastic Leukemia/Lymphoma, Stage III T Lymphoblastic Leukemia/Lymphoma | Phase 2 / Phase 3 | Not yet recruiting | Children's Oncology Group | 1708 | 2026-08-28 | 2026-07-30 |
| Efficacy and Safety of CD7 CAR-T in Newly Diagnosed High-Risk T-LBL/ALL CD7 CAR-T cell intravenous infusion - T Lymphoblastic Lymphoma, T Acute Lymphoblastic Leukemia | Early Phase 1 | Not yet recruiting | Institute of Hematology & Blood Diseases Hospital, China | 10 | 2026-03-15 | 2026-03-17 |
| Allo-HSCT vs ASCT in Adult T-LBL ASCT, Allo-HSCT - T Lymphoblastic Lymphoma | Not applicable | Not yet recruiting | Peking University People's Hospital | 230 | 2025-01-01 | 2024-12-19 |
| Adding Targeted Drugs to Usual Chemotherapy for Adults With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia (T-ALL) and T-Cell Lymphoblastic Lymphoma (T-LBL) Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy - T Acute Lymphoblastic Leukemia, T Lymphoblastic Lymphoma | Phase 2 | Withdrawn | National Cancer Institute (NCI) | 2024-08-09 | 2024-05-17 | |
| Study to Test OBI-3424 in Patients With T-Cell Acute Lymphoblastic Leukemia (T-ALL) or T-Cell Lymphoblastic Lymphoma (T-LBL) AKR1C3-activated Prodrug AST-3424, Biopsy Procedure, Biospecimen Collection - Recurrent T Acute Lymphoblastic Leukemia, Refractory T Acute Lymphoblastic Leukemia | Phase 1 / Phase 2 | Active not recruiting | SWOG Cancer Research Network | 67 | 2021-02-08 | 2026-09-01 |
| Etoposide, Prednisone, Vincristine Sulfate, Cyclophosphamide, and Doxorubicin Hydrochloride With Asparaginase in Treating Patients With Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma Asparaginase, Cyclophosphamide, Doxorubicin Hydrochloride - B Acute Lymphoblastic Leukemia, B Lymphoblastic Lymphoma | Phase 2 | Withdrawn | University of Washington | 2018-07-01 | 2018-11-14 | |
| Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies Cyclophosphamide, Filgrastim, Fludarabine Phosphate - Acute Biphenotypic Leukemia, Acute Erythroid Leukemia in Remission | Phase 2 | Terminated | Fred Hutchinson Cancer Center | 46 | 2010-05-19 | 2023-01-23 |
| Combination Chemotherapy and Nelarabine in Treating Patients With T-cell Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma Cyclophosphamide, Cytarabine, Dexamethasone - T Acute Lymphoblastic Leukemia, T Lymphoblastic Lymphoma | Phase 2 | Recruiting | M.D. Anderson Cancer Center | 160 | 2007-07-11 | 2026-10-08 |
| Combination Chemotherapy in Treating Young Patients With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia or T-cell Lymphoblastic Lymphoma Asparaginase, Cyclophosphamide, Cytarabine - T Acute Lymphoblastic Leukemia, T Lymphoblastic Lymphoma | Phase 3 | Completed | National Cancer Institute (NCI) | 1895 | 2007-01-30 | 2026-06-23 |
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (9) · Burkitt Lymphoma (2) · Lymphoma (2) · Hodgkin Disease (1) · Leukemia, Biphenotypic, Acute (1) · Lymphoma, B-Cell, Marginal Zone (1) · Lymphoma, Follicular (1) · Lymphoma, Large-Cell, Anaplastic (1) · Lymphoma, Mantle-Cell (1) · Multiple Myeloma (1) · Myelodysplastic Syndromes (1) · Precursor B-Cell Lymphoblastic Leukemia-Lymphoma (1) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (1)
Hematologic Diseases (9) · Hemic and Lymphatic Diseases (9) · Immune System Diseases (9) · Immunoproliferative Disorders (9) · Leukemia (9) · Leukemia, Lymphoid (9) · Lymphatic Diseases (9) · Lymphoproliferative Disorders (9) · Neoplasms (9) · Neoplasms by Histologic Type (9) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (8) · DNA Virus Infections (2) · Epstein-Barr Virus Infections (2) · Herpesviridae Infections (2) · Infections (2)
Cyclophosphamide (6) · Doxorubicin (5) · Vincristine (5) · Asparaginase (4) · Calcium Dobesilate (4) · Cytarabine (4) · Dexamethasone (4) · Mercaptopurine (4) · Methotrexate (4) · Prednisone (4) · auricularum (4) · deltacortene (4) · dexamethasone 21-phosphate (4) · dexamethasone acetate (4) · merphos (4)
National Cancer Institute (NCI) (2) · Children's Oncology Group (1) · Fred Hutchinson Cancer Center (1) · Institute of Hematology & Blood Diseases Hospital, China (1) · M.D. Anderson Cancer Center (1) · Peking University People's Hospital (1) · SWOG Cancer Research Network (1) · University of Washington (1)
United States (5) · Australia (1) · Canada (1) · New Zealand (1) · Switzerland (1)
Anjali S Advani (1) · Farhad Ravandi-Kashani (1) · Keith J August (1) · Kristen M O'Dwyer (1) · Rachel B. Salit (1) · Ryan Cassaday (1) · Stuart S Winter (1)
PMID 30138085, PMID 32552472, PMID 32813610, PMID 34302711, PMID 36603187, PMID 37556734, PMID 40533067, PMID 41592282, PMID 42085640
U10CA180886 (2), U10CA180888 (2), P30CA015704 (1), U10CA098543 (1)