5 completed, 2 terminated. 3 Phase 2, 2 Not applicable, 1 Early Phase 1, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 3 | Completed 3 |
| Not applicable | 2 | Completed 2 |
| Early Phase 1 | 1 | Terminated 1 |
| Phase 1 | 1 | Terminated 1 |
Follow Stage II Oropharyngeal Squamous Cell Carcinoma: new trials by email Literature Review of Stage II Oropharyngeal Squamous Cell Carcinoma trials Research Report on Stage II Oropharyngeal Squamous Cell Carcinoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Nivolumab, Carboplatin, and Paclitaxel in Treating Patients With Stage III-IV Head and Neck Squamous Cell Carcinoma That Can Be Removed by Surgery Paclitaxel, Carboplatin, Nivolumab - Name Human Papillomavirus Positive Oropharyngeal Squamous Cell Carcinoma, Stage II Oropharyngeal Squamous Cell Carcinoma | Phase 2 | Completed | Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University | 34 | 2017-11-13 | 2025-04-24 |
| Prepare to Care, A Supported Self-Management Intervention for Head and Neck Cancer CaregiversHead and Neck Cancer Communication Intervention, Watch video, Module completion of the Prepare to Care kit - Caregiver, Malignant Head and Neck Neoplasm | Not applicable | Completed | Wake Forest University Health Sciences | 35 | 2017-05-15 | 2023-01-09 |
| Durvalumab Before Surgery in Treating Patients With Oral Cavity or Oropharynx Cancer Durvalumab, Laboratory Biomarker Analysis, Therapeutic Conventional Surgery - Human Papillomavirus Infection, Stage I Oral Cavity Squamous Cell Carcinoma | Early Phase 1 | Terminated | Wake Forest University Health Sciences | 17 | 2017-01-01 | 2025-03-17 |
| Ganetespib Window of Opportunity Study in Head and Neck Cancers Ganetespib, Therapeutic Conventional Surgery, Laboratory Biomarker Analysis - Stage I Hypopharyngeal Squamous Cell Carcinoma, Stage I Laryngeal Squamous Cell Carcinoma | Phase 1 | Terminated | Emory University | 3 | 2014-12-01 | 2016-07-26 |
| Radiation Therapy and Docetaxel in Treating Patients With HPV-Related Oropharyngeal Cancer Docetaxel, Hyperfractionation, Intensity-Modulated Radiation Therapy - Human Papillomavirus Infection, Stage I Oropharyngeal Squamous Cell Carcinoma | Phase 2 | Completed | Mayo Clinic | 81 | 2013-09-04 | 2026-02-10 |
| Dexamethasone in Reducing Oral Pain and Dry Mouth After Surgery in Patients With Oropharyngeal Cancer Dexamethasone, Placebo, Quality-of-Life Assessment - Dysphagia, Pain | Not applicable | Completed | OHSU Knight Cancer Institute | 76 | 2012-12-01 | 2018-06-19 |
| Soy Isoflavones in Preventing Head and Neck Cancer Recurrence in Patients With Stage I-IV Head and Neck Cancer Undergoing Surgery Laboratory Biomarker Analysis, Soy Isoflavones, Survey Administration - Recurrent Hypopharyngeal Squamous Cell Carcinoma, Recurrent Laryngeal Squamous Cell Carcinoma | Phase 2 | Completed | National Cancer Institute (NCI) | 55 | 2009-07-01 | 2016-10-24 |
Squamous Cell Carcinoma of Head and Neck (7) · Lymphoid Interstitial Pneumonia (2) · Papillomavirus Infections (2) · Deglutition Disorders (1) · Head and Neck Neoplasms (1) · Pain (1) · Tongue Neoplasms (1)
Carcinoma (7) · Carcinoma, Squamous Cell (7) · Neoplasms (7) · Neoplasms by Histologic Type (7) · Neoplasms by Site (7) · Neoplasms, Glandular and Epithelial (7) · Head and Neck Neoplasms (6) · Pathological Conditions, Signs and Symptoms (3) · Communicable Diseases (2) · DNA Virus Infections (2) · Disease Attributes (2) · Genital Diseases (2) · Infections (2) · Pathologic Processes (2) · Sexually Transmitted Diseases (2)
Calcium Dobesilate (1) · Carboplatin (1) · Dexamethasone (1) · Disulfides (1) · Docetaxel (1) · Educational Status (1) · Immunoglobulin G (1) · Methods (1) · Nivolumab (1) · Paclitaxel (1) · Radiotherapy, Intensity-Modulated (1) · STA 9090 (1) · Soybean Proteins (1) · Taxes (1) · auricularum (1)
Wake Forest University Health Sciences (2) · Emory University (1) · Mayo Clinic (1) · National Cancer Institute (NCI) (1) · OHSU Knight Cancer Institute (1) · Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University (1)
United States (7)
Chandylen Nightingale (1) · Daniel Clayburgh (1) · Daniel Ma (1) · Greg Wolf (1) · Jennifer Johnson, MD, PhD (1) · Mercedes Porosnicu (1) · Nabil F. Saba, MD (1)
PMID 28850681, PMID 31163012, PMID 35575280
P30CA012197 (2), P30CA046592 (1), P30CA069533 (1), R03CA208560 (1)