3 recruiting, 1 withdrawn. 4 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Early Phase 1 | 4 | Recruiting 3, Withdrawn 1 |
Follow SLE: new trials by email Literature Review of SLE trials Research Report on SLE
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Safety and Efficacy of ONT01 in Lupus ONT01 is a small molecule CD11b modulator. - Lupus Nephritis (LN), Lupus Nephritis - WHO Class III | Early Phase 1 | Recruiting | Hospital for Special Surgery, New York | 61 | 2026-09-04 | 2025-11-20 |
| A Study of Anti-CD19/BCMA Universal CAR-T Cell Therapy RD06-05 in Patients With Autoimmune Diseases. RD06-05 CART Cell Injection - SLE, LN | Early Phase 1 | Recruiting | Nanjing Bioheng Biotech Co., Ltd. | 96 | 2025-07-24 | 2026-08-03 |
| Clinical Study on Targeted CD19/BCMA CAR-T Therapy for Autoimmune Diseases RD06-05 CART Cell Injection - SLE, Systemic Sclerosis | Early Phase 1 | Recruiting | Nanjing Bioheng Biotech Co., Ltd. | 18 | 2025-01-03 | 2026-02-02 |
| A Study of RD06-04 in Patients With Active Autoimmune Diseases RD06-04 cell infusion - SLE, Sclerosis | Early Phase 1 | Withdrawn | Nanjing Bioheng Biotech Co., Ltd. | 2024-08-31 | 2026-02-03 |
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis (3) · Anti-Glomerular Basement Membrane Disease (1) · Glomerulonephritis, IGA (1) · Lupus Erythematosus, Systemic (1) · Lupus Nephritis (1) · Neuromyelitis Optica (1) · Scleroderma, Systemic (1) · Sclerosis (1)
Autoimmune Diseases (4) · Immune System Diseases (4) · Skin and Connective Tissue Diseases (4) · Cardiovascular Diseases (3) · Skin Diseases (3) · Skin Diseases, Vascular (3) · Systemic Vasculitis (3) · Vascular Diseases (3) · Vasculitis (3) · Connective Tissue Diseases (2) · Female Urogenital Diseases (2) · Female Urogenital Diseases and Pregnancy Complications (2) · Glomerulonephritis (2) · Kidney Diseases (2) · Male Urogenital Diseases (2)
Nanjing Bioheng Biotech Co., Ltd. (3) · Hospital for Special Surgery, New York (1)
China (3) · United States (1)