4802 completed, 1302 terminated, 1014 recruiting, 1014 unknown. 9506 Phase 2, 1833 Phase 1, 505 Phase 3.
Follow Skin and Connective Tissue Diseases: new trials by email Literature Review of Skin and Connective Tissue Diseases trials Research Report on Skin and Connective Tissue Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Open-label Pilot Clinical Trial of Oral Ivermectin to Treat Atopic Dermatitis Ivermectin Pill - Atopic Dermatitis | Phase 2 | Withdrawn | Stanford University | 2030-12-01 | 2024-12-02 | |
| Efficacy and Safety of SR-T100 Gel in Common Warts (CW) Patients Vehicle gel, SR-T100 gel with 1.0% of SM, SR-T100 gel with 2.3% of SM - Common Wart | Phase 2 | Suspended | G&E Herbal Biotechnology Co., LTD | 102 | 2030-09-01 | 2023-09-14 |
| Cannabichromene Safety in Rheumatoid Arthritis Cannabichromene - Arthritis, Rheumatoid | Phase 1 / Phase 2 | Withdrawn | Crystal Lederhos Smith | 2028-07-15 | 2026-09-23 | |
| Epidermal Growth Factor Receptor Inhibition for Keratinopathies Erlotinib - Epidermolytic Ichthyosis, Palmoplantar Keratoderma | Phase 1 / Phase 2 | Not yet recruiting | Northwestern University | 44 | 2027-07-01 | 2026-08-03 |
| Neu Direction: Testing the Efficacy of Adding HER Inhibition to Standard of Care in Metastatic MLH1-low Endocrine-resistant ER+/HER2- Breast Cancer Neratinib + endocrine therapy, Endocrine therapy may include one of the following therapies: letrozole, anastrozole, exemestane, tamoxifen or fulvestrant, CDK4/6 + Endocrine therapy - Metastatic Invasive Breast Cancer, Resistant Breast Cancer | Phase 2 | Not yet recruiting | University of California, San Diego | 150 | 2027-07-01 | 2026-07-27 |
| Combination Immunotherapy Targeting Melanoma Antigen-specific CAR T, CTL and DCvac to treat melanoma. - Melanoma | Phase 1 / Phase 2 | Not yet recruiting | Shenzhen Geno-Immune Medical Institute | 30 | 2027-06-30 | 2026-10-30 |
| HEADWATERS: Gemcitabine vs Paclitaxel in Metastatic Triple-Negative Breast Cancer in Women of African Ancestry. Gemcitabine (1000 mg/m^2), Paclitaxel 80 mg/m2 weekly - Triple Negative Breast Cancer, Metastatic Triple-negative Breast Cancer | Phase 2 | Not yet recruiting | The University of The West Indies | 750 | 2027-06-01 | 2026-09-22 |
| Trial of Temozolomide in BAP1 Mutated Patients With Advanced or Metastatic Cutaneous Melanoma Temozolomide (TMZ) - Cutaneous Melanoma | Phase 2 | Not yet recruiting | Assistance Publique Hopitaux De Marseille | 28 | 2027-06-01 | 2026-09-08 |
| Multi-4SCAR-T Therapy Targeting Breast Cancer 4SCAR T cells - Breast Cancer | Phase 1 / Phase 2 | Not yet recruiting | Shenzhen Geno-Immune Medical Institute | 100 | 2027-06-01 | 2026-11-02 |
| A Study on How to Safely Guide Surgery for Melanoma and Similar Skin Tumors in Children Using Pathology and Genetic Information Biospecimen Collection, Chest Radiography, Computed Tomography - Clinical Stage 0 Cutaneous Melanoma AJCC v8, Clinical Stage I Cutaneous Melanoma AJCC v8 | Phase 2 | Recruiting | Children's Oncology Group | 51 | 2027-05-15 | 2026-09-24 |
| Study of Trastuzumab Deruxtecan in Combination With Stereotactic Radiosurgery in Patients With HER2-Positive Metastatic Breast Cancer and First Diagnosis of Brain Metastases (HERBRAIN) SRS/fSRT+T-Dxd - Breast Cancer (Advanced/Metastatic) | Phase 2 | Not yet recruiting | Azienda Ospedaliero-Universitaria Careggi | 60 | 2027-05-15 | 2026-10-29 |
| Determine the Dose-dependent Efficacy and Safety of EC-18 in Patients With Moderate to Severe Atopic Dermatitis EC-18, Placebo EC-18 - Atopic Dermatitis | Phase 2 | Not yet recruiting | Enzychem Lifesciences Corporation | 150 | 2027-05-01 | 2026-08-28 |
| Comparative Study on Unani Formulation Vs Active Control in Plaque Psoriasis Marham Asfedaj, Mundij wa Mushil Sawda (Unani Oral decoction), Coal tar 1% & Salicylic acid 3 % solution - Chronic Plaque Psoriasis, Plaque Psoriasis | Phase 2 | Not yet recruiting | National Institute of Unani Medicine, Bengaluru | 54 | 2027-04-01 | 2026-09-25 |
| Phase 2b of RAPA-201 Cell Therapy in Post-PD-(L)-1 Melanoma RAPA-201 Rapamycin Resistant T Cells, Chemotherapy Prior to RAPA-201 Therapy - Malignant Melanoma With Metastasis, Malignant Melanoma | Phase 2 | Not yet recruiting | Rapa Therapeutics LLC | 65 | 2027-03-01 | 2026-03-19 |
| Low-Dose Apatinib Plus Chemotherapy in ADC-Pretreated HER2-Positive and HER2-Low Advanced Breast Cancer Apatinib mesylate, Physician's choice chemotherapy - Breast Neoplasms, Advanced Breast Cancer | Phase 2 | Not yet recruiting | Yunnan Cancer Hospital | 56 | 2027-03-01 | 2026-10-30 |
| Semaglutide for Weight Management During Hormone Therapy for Early Breast Cancer Semaglutide (Wegovy®) - Breast Cancer (Early Breast Cancer), Obesity | Phase 2 | Not yet recruiting | Aarhus University Hospital | 32 | 2027-03-01 | 2026-11-02 |
| The Primary Objective of the Trial is to Evaluate the Effect of the Addition of Belantamab Mafodotin to Standard of Care Therapy on the Titres of Serum Anti-dsDNA Antibodies in Patients With Previously Treated SLE. belantamab mafodotin to the existing stable standard background therapy - SLE - Systemic Lupus Erythematosus | Phase 2 | Not yet recruiting | Medical Association for the Study of Cancer Biology and Treatment | 12 | 2027-02-01 | 2026-09-28 |
| Single Injection of rAAV9-CMV-hNAGLUop Gene for Patients With Mucopolysaccharidosis (MPS) IIIB rAAV9-CMV-hNAGLUop - Sanfilippo Syndrome (MPS III) | Phase 1 / Phase 2 | Not yet recruiting | NeuroGT | 9 | 2027-01-18 | 2026-09-14 |
| Regenerative Medicine for Joint Hypermobility and Instability Dextrose 20% Prolotherapy, Autologous Platelet-Rich Plasma, Doxycycline Hyclate Injectable (Investigational) - Ehlers-Danlos Syndrome Hypermobility Type (hEDS), Ehlers-Danlos Syndrome (EDS) | Phase 1 / Phase 2 | Not yet recruiting | Manhattan Pain Medicine, PLLC | 100 | 2027-01-15 | 2026-10-06 |
| Interest of a Targeted Therapy for the Treatment of a Severe Form of Hypersensitivity to Drug (DRESS Syndrome) Benralizumab 30 MG/ML [Fasenra], Placebo Comparator: Placebo-Control Arm 0.9% Sodium Chloride - DRESS Syndrome | Phase 2 | Not yet recruiting | University Hospital, Lille | 96 | 2027-01-06 | 2026-05-15 |
Showing 20 of 9506. Sign in to see all of them.
Breast Neoplasms (3588) · Melanoma (1334) · Triple Negative Breast Neoplasms (606) · Arthritis, Rheumatoid (568) · Dermatitis, Atopic (401) · Neoplasm Metastasis (345) · Psoriasis (299) · Carcinoma, Non-Small-Cell Lung (273) · Lupus Erythematosus, Systemic (268) · Neoplasms (261) · Ovarian Neoplasms (204) · Colorectal Neoplasms (161) · Scleroderma, Systemic (161) · Lung Neoplasms (150) · Acne Vulgaris (141)
Skin Diseases (8217) · Neoplasms by Site (5327) · Neoplasms (5224) · Breast Diseases (3980) · Immune System Diseases (1814) · Neoplasms by Histologic Type (1778) · Connective Tissue Diseases (1531) · Neoplasms, Nerve Tissue (1388) · Neoplasms, Germ Cell and Embryonal (1387) · Neuroectodermal Tumors (1387) · Neuroendocrine Tumors (1348) · Nevi and Melanomas (1338) · Skin Neoplasms (1294) · Pathological Conditions, Signs and Symptoms (1288)
Cyclophosphamide (473) · Paclitaxel (397) · Trastuzumab (386) · pembrolizumab (321) · Docetaxel (295) · Carboplatin (269) · Capecitabine (256) · Nivolumab (200) · Letrozole (199) · Doxorubicin (197) · Fulvestrant (194) · Bevacizumab (184) · Ipilimumab (171) · Gemcitabine (129) · Methotrexate (125)
National Cancer Institute (NCI) (254) · Novartis Pharmaceuticals (151) · Pfizer (140) · M.D. Anderson Cancer Center (130) · Fudan University (123) · Hoffmann-La Roche (92) · Memorial Sloan Kettering Cancer Center (88) · GlaxoSmithKline (83) · Bristol-Myers Squibb (77) · Eli Lilly and Company (76) · AstraZeneca (72) · Dana-Farber Cancer Institute (71) · National Institute of Allergy and Infectious Diseases (NIAID) (66) · Amgen (62) · Merck Sharp & Dohme LLC (56)
United States (4976) · China (1055) · Germany (942) · Canada (836) · Spain (816) · France (804) · United Kingdom (739) · Poland (584) · Italy (560) · Australia (513) · Belgium (422) · South Korea (366) · Netherlands (330) · Japan (324) · Hungary (304)
PMID 33687069, PMID 36648215, PMID 32816215, PMID 33127856, PMID 34870800, PMID 36526796, PMID 36600185, PMID 36601090, PMID 36931693, PMID 38979716, PMID 39192350, PMID 25047021, PMID 28143815, PMID 34037241, PMID 38958913, PMID 25667295, PMID 33283264, PMID 36326435, PMID 22555974, PMID 37528520, PMID 40938675, PMID 26275429, PMID 28324110, PMID 28941219, PMID 31194872, PMID 31401903, PMID 34754076, PMID 35544084, PMID 19097774, PMID 23861247, PMID 24529560, PMID 24983357, PMID 25092775, PMID 29463520, PMID 30627694, PMID 30842122, PMID 31838010, PMID 32747469, PMID 33011075, PMID 33084020, PMID 33736679, PMID 34041702, PMID 34677608, PMID 34706874, PMID 36205910, PMID 36408587, PMID 37316690, PMID 37453736, PMID 37747626, PMID 37917289
2023 (119), 2016 (85), 2018 (85), 2025 (77), 2019 (70), 2014 (61), 2015 (58), 2017 (58), 2009 (43), 2008 (37), P30CA033572 (24), U10CA032102 (18), 2005 (17), P30CA015083 (17), P30CA015704 (16)