4 completed, 1 active not recruiting, 1 recruiting, 1 withdrawn. 7 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 7 | Completed 4, Active not recruiting 1, Recruiting 1, Withdrawn 1 |
Follow Severe Asthma: new trials by email Literature Review of Severe Asthma trials Research Report on Severe Asthma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Clinical Study to Evaluate the Efficacy and Safety of Frevecitinib (KN-002) in Patients With Severe Asthma Frevecitinib, Placebo - Severe Asthma | Phase 2 | Recruiting | Kinaset Therapeutics Inc | 512 | 2026-07-16 | 2026-07-28 |
| A Long-Term Safety and Efficacy Study of Verekitug (UPB-101) in Adult Participants With Severe Asthma (VALOUR) Verekitug, Placebo - Severe Asthma | Phase 2 | Active not recruiting | Upstream Bio Inc. | 396 | 2025-05-21 | 2026-05-14 |
| A Study to Investigate the Efficacy and Safety of Verekitug (UPB-101) in Adult Participants With Severe Asthma (VALIANT) Verekitug (UPB-101), Placebo - Severe Asthma | Phase 2 | Completed | Upstream Bio Inc. | 479 | 2024-02-27 | 2026-05-01 |
| Evaluate the Efficacy and Safety of TQC2731 Injection in Patients With Severe Asthma. TQC2731 injection, Placebo - Severe Asthma | Phase 2 | Completed | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 205 | 2022-09-23 | 2025-11-20 |
| Evaluate the Efficacy and Safety of FB704A in Adult With Severe Asthma FB704A placebo, FB704A - Severe Asthma | Phase 2 | Completed | Oneness Biotech Co., Ltd. | 21 | 2021-09-30 | 2026-07-09 |
| Reslizumab in Patients With Severe Asthma Who Failed to Respond to Omalizumab Reslizumab - Severe Asthma | Phase 2 | Completed | Sociedad Española de Neumología y Cirugía Torácica | 30 | 2017-04-20 | 2018-05-16 |
| Trial of Simvastatin for the Treatment of Severe Asthma Simvastatin, Placebo - Severe Asthma | Phase 2 | Withdrawn | University of California, Davis | 2013-12-01 | 2017-09-26 |
Asthma (7) · Bronchial Diseases (2) · Lung Diseases (2) · Respiratory Tract Diseases (2)
Hypersensitivity (7) · Hypersensitivity, Immediate (7) · Immune System Diseases (7) · Lung Diseases, Obstructive (7) · Respiratory Hypersensitivity (7) · Bronchial Diseases (5) · Lung Diseases (5) · Respiratory Tract Diseases (5)
Simvastatin (1) · reslizumab (1)
Upstream Bio Inc. (2) · Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (1) · Kinaset Therapeutics Inc (1) · Oneness Biotech Co., Ltd. (1) · Sociedad Española de Neumología y Cirugía Torácica (1) · University of California, Davis (1)
United States (4) · Spain (3) · Argentina (2) · Bulgaria (2) · Canada (2) · Chile (2) · Czechia (2) · Germany (2) · Italy (2) · Japan (2) · Poland (2) · South Africa (2) · South Korea (2) · Ukraine (2) · United Kingdom (2)
Justin Salciccioli, MD (2) · Jessica Ho, Director (1)
2023 (1)