29 completed. 29 Phase 1, 11 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 29 | Completed 29 |
| Phase 2 | 11 | Completed 11 |
Follow Peritoneal Neoplasms: new trials by email Literature Review of Peritoneal Neoplasms trials Research Report on Peritoneal Neoplasms
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study of Radspherin® in Recurrent Ovarian Cancer Subjects With Peritoneal Carcinomatosis Radspherin - Peritoneal Carcinomatosis, Ovarian Cancer | Phase 1 | Completed | Oncoinvent Solutions AS | 21 | 2020-06-08 | 2026-04-17 |
| Talimogene Laherparepvec for the Treatment of Peritoneal Surface Malignancies Talimogene Laherparepvec - Peritoneal Surface Malignancy | Phase 1 | Completed | Dan Blazer III, M.D. | 28 | 2019-05-23 | 2024-11-20 |
| Feasibility of the LUM Imaging System for Peritoneal Surface Malignancies LUM Imaging System - Peritoneal Metastases | Phase 1 / Phase 2 | Completed | Lumicell, Inc. | 18 | 2019-03-18 | 2026-01-16 |
| Intraperitoneal Paclitaxel Plus Systemic mFOLFOX6 Paclitaxel, mFOLFOX6 regimen - Gastric Cancer Stage IV, Peritoneal Carcinomatosis | Phase 1 / Phase 2 | Completed | Seoul National University Bundang Hospital | 35 | 2018-12-24 | 2023-12-05 |
| Nivolumab With or Without Ipilimumab in Treating Patients With Recurrent or High Grade Gynecologic Cancer With Metastatic Peritoneal Carcinomatosis Ipilimumab, Laboratory Biomarker Analysis, Nivolumab - Malignant Peritoneal Neoplasm, Malignant Retroperitoneal Neoplasm | Phase 1 | Completed | M.D. Anderson Cancer Center | 26 | 2018-09-21 | 2025-05-22 |
| PIPAC Nab-pac for Stomach, Pancreas, Breast and Ovarian Cancer PIPAC with Abraxane - Peritoneal Carcinomatosis, Ovarian Cancer Stage IIIB | Phase 1 | Completed | University Hospital, Ghent | 20 | 2017-09-16 | 2023-11-07 |
| Phase I Study of Cantrixil in Patients With Ovarian Cancer, Fallopian Tube Cancer or Primary Peritoneal Cancer. Part A: Dose Escalation of Cantrixil, Part B: Expansion Cohort of Cantrixil - Ovarian Neoplasms, Fallopian Tube Neoplasms | Phase 1 | Completed | Kazia Therapeutics Limited | 32 | 2016-12-05 | 2024-09-19 |
| Trial of Intraperitoneal (IP) Oxaliplatin in Combination With Intravenous FOLFIRI Oxaliplatin - Colorectal Cancer, Appendix Cancer | Phase 1 | Completed | University of Massachusetts, Worcester | 14 | 2016-07-01 | 2022-05-31 |
| Olvi-Vec Oncolytic Immunotherapy in Patients With Recurrent or Refractory Ovarian Cancer Olvi-Vec, Platinum-doublet with or without bevacizumab - Ovarian Cancer, Peritoneal Carcinomatosis | Phase 1 / Phase 2 | Completed | Genelux Corporation | 46 | 2016-05-01 | 2026-06-12 |
| Durvalumab and Tremelimumab in Combination With First-Line Chemotherapy in Advanced Solid Tumors paclitaxel + carboplatin, carboplatin + etoposide, gemcitabine + carboplatin - Small Cell Lung Carcinoma, Carcinoma, Squamous Cell of Head and Neck | Phase 1 | Completed | AstraZeneca | 32 | 2016-04-28 | 2020-08-20 |
| Study of Efficacy and Safety of Laparoscopic Intra-abdominal Chemotherapy (PIPAC) Performed in Patients With Peritoneal Carcinomatosis From Colorectal, Ovarian, Gastric Cancer and Primary Peritoneal Tumors Pressurized IntraPeritoneal Air-flow Chemotherapy (PIPAC) fixed repeated dose, Pressurized IntraPeritoneal Air-flow Chemotherapy (PIPAC) increasing single dose - Peritoneal Carcinomatosis | Phase 1 / Phase 2 | Completed | Fondazione del Piemonte per l'Oncologia | 105 | 2015-10-01 | 2020-09-17 |
| Immunotoxin in Peritoneal Carcinomatosis- ImmunoPeCa Trial MOC31PE Immunotoxin - Colorectal Neoplasms | Phase 1 / Phase 2 | Completed | Oslo University Hospital | 15 | 2014-08-01 | 2017-05-30 |
| αDC1 Vaccine + Chemokine Modulatory Regimen (CKM) as Adjuvant Treatment of Peritoneal Surface Malignancies DC vaccine, Celecoxib, Interferon Alfa-2b - Malignant Neoplasm of Pancreas Metastatic to Peritoneal Surface, Malignant Peritoneal Mesothelioma | Phase 1 / Phase 2 | Completed | David Bartlett | 64 | 2014-07-01 | 2020-07-20 |
| Intraperitoneal Docetaxel With Cisplatin and TS-ONE for Gastric Cancer With Peritoneal Carcinomatosis Intraperitoneal docetaxel - Gastric Cancer, Peritoneal Carcinomatosis | Phase 1 | Completed | The University of Hong Kong | 12 | 2013-12-01 | 2018-05-04 |
| Imaging of Peritoneal Carcinomatosis From Ovarian Carcinoma Patients iv injection of ICG - Ovarian Cancer, Peritoneal Carcinomatosis | Phase 1 / Phase 2 | Completed | Jules Bordet Institute | 10 | 2013-03-01 | 2014-10-15 |
| A Study of GL-ONC1, an Oncolytic Vaccinia Virus, in Patients With Advanced Peritoneal Carcinomatosis GL-ONC1 - Peritoneal Carcinomatosis | Phase 1 / Phase 2 | Completed | Genelux GmbH | 9 | 2012-02-01 | 2025-04-30 |
| A Phase 1 Study of CC-486 as a Single Agent and in Combination With Carboplatin or ABI-007 in Subjects With Relapsed or Refractory Solid Tumors CC-486, Carboplatin, ABI-007 - Urinary Bladder Neoplasms, Carcinoma, Transitional Cell | Phase 1 | Completed | Celgene | 169 | 2011-11-29 | 2019-11-12 |
| Safety Study of ²¹²Pb-TCMC-Trastuzumab Radio Immunotherapy ²¹²Pb-TCMC-Trastuzumab, trastuzumab - Breast Neoplasms, Peritoneal Neoplasms | Phase 1 | Completed | Orano Med LLC | 18 | 2011-07-01 | 2016-09-30 |
| BIBF 1120 + Carboplatin/Pegylated Liposomal Doxorubicin (PLD) in Patients With Advanced Ovarian Cancer, Fallopian Tube Carcinoma or Primary Peritoneal Cancer BIBF 1120 + PLD 30 mg/m2 + CBDCA AUC5 mg/mL*min, BIBF 1120+ PLD 30 mg/m2 + CBDCA AUC5 mg/mL*min - Ovarian Neoplasms, Peritoneal Neoplasms | Phase 1 | Completed | Boehringer Ingelheim | 19 | 2011-03-15 | 2025-02-13 |
| Veliparib and Radiation Therapy in Treating Patients With Advanced Solid Malignancies With Peritoneal Carcinomatosis, Epithelial Ovarian, Fallopian, or Primary Peritoneal Cancer Laboratory Biomarker Analysis, Quality-of-Life Assessment, Radiation Therapy - Adult Solid Neoplasm, Peritoneal Carcinomatosis | Phase 1 | Completed | National Cancer Institute (NCI) | 34 | 2011-01-01 | 2017-11-21 |
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Ovarian Neoplasms (18) · Fallopian Tube Neoplasms (9) · Stomach Neoplasms (6) · Neoplasms (3) · Pancreatic Neoplasms (3) · Adenocarcinoma (2) · Breast Neoplasms (2) · Carcinoma (2) · Carcinoma, Ovarian Epithelial (2) · Carcinoma, Pancreatic Ductal (2) · Colorectal Neoplasms (2) · Gastrointestinal Neoplasms (2) · Vaccinia (2) · Adrenocortical Carcinoma (1)
Abdominal Neoplasms (29) · Digestive System Diseases (29) · Neoplasms by Site (29) · Peritoneal Diseases (29) · Digestive System Neoplasms (28) · Neoplasms (26) · Adnexal Diseases (18) · Endocrine Gland Neoplasms (18) · Endocrine System Diseases (18) · Female Urogenital Diseases (18) · Female Urogenital Diseases and Pregnancy Complications (18) · Genital Diseases (18) · Genital Diseases, Female (18) · Genital Neoplasms, Female (18) · Gonadal Disorders (18)
Cisplatin (5) · 130-nm albumin-bound paclitaxel (3) · Albumin-Bound Paclitaxel (3) · Carboplatin (3) · Oxaliplatin (3) · Cytoreduction Surgical Procedures (2) · Fluorouracil (2) · Paclitaxel (2) · 1-dodecylpyridoxal (1) · 4-(para-hydroxyphenyl)-7,4'-dihydroxy-3',5'-dimethoxy-8-methylisoflavan (1) · Acids (1) · AlkB Homolog 2, Alpha-Ketoglutarate-Dependent Dioxygenase (1) · Azacitidine (1) · Bevacizumab (1) · CP protocol (1)
National Cancer Institute (NCI) (4) · M.D. Anderson Cancer Center (3) · AGO Study Group (1) · AstraZeneca (1) · Boehringer Ingelheim (1) · Celgene (1) · City of Hope Medical Center (1) · CritiTech, Inc. (1) · Dan Blazer III, M.D. (1) · David Bartlett (1) · Fondazione del Piemonte per l'Oncologia (1) · Genelux Corporation (1) · Genelux GmbH (1) · Hospices Civils de Lyon (1) · Jules Bordet Institute (1)
United States (17) · Belgium (3) · Spain (3) · France (2) · Germany (2) · Norway (2) · South Korea (2) · Australia (1) · Canada (1) · China (1) · Italy (1) · Japan (1) · Netherlands (1)
Amir A Jazaeri (1) · Andrea Hayes-Jordan, MD (1) · Bradley Switzer, MD (1) · Charles Levenback, MD (1) · Dan Blazer, MD (1) · David L Bartlett, MD (1) · Dr Don Dizon, MD, FACP (1) · Gabriel Liberale, MD (1) · Gary Johnson, M.D. (1) · Gordan Bray, M.D., Ph.D (1) · Hyung-Ho Kim, M.D., PhD. (1) · Isabelle Veys, MD (1) · Jacobus Pfisterer, Prof. Dr. (1)
PMID 21424369, PMID 29773661, PMID 30623229, PMID 33037105, PMID 34070561, PMID 34206826, PMID 35843174, PMID 37227734, PMID 37489066, PMID 38471508, PMID 41349345, PMID 42383154
2018 (1), P01CA132714 (1), P30CA006973 (1), U01CA070095 (1), U01CA132123 (1), UM1CA186644 (1), UM1CA186691 (1)