6 completed, 5 recruiting, 5 unknown, 2 active not recruiting. 11 Not applicable, 1 Phase 3, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 11 | Completed 3, Recruiting 3, Unknown 3, Active not recruiting 2 |
| Phase 3 | 1 | Unknown 1 |
| Phase 4 | 1 | Not yet recruiting 1 |
Follow Mullerian aplasia: new trials by email Literature Review of Mullerian aplasia trials Research Report on Mullerian aplasia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Vaginal Lactobacillus for Postoperative Microecology and Mucosal Repair in MRKH Syndrome postoperative application of vaginal Lactobacillus capsule, routine care - Mayer Rokitansky Kuster Hauser Syndrome | Phase 4 | Not yet recruiting | Obstetrics & Gynecology Hospital of Fudan University | 32 | 2026-11-01 | 2026-10-08 |
| Evaluation of the Quality of Life and Gynecological Follow-up of Patients Treated for Mayer-Rokitansky-Küster-Hauser (MRKH) Syndrome Questionnaires, Semi-directed interview - Mrkh Syndrome | Recruiting | University Hospital, Toulouse | 102 | 2026-03-04 | 2026-04-02 | |
| Clinical and Imaging Features in MRKH Syndrome Mayer Rokitansky Kuster Hauser Syndrome, Müllerian Agenesis | Not yet recruiting | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 25 | 2026-01-12 | 2026-01-07 | |
| Neovaginoplasty Using Photoinduced-imine-crosslink Hydrogel in MRKH Patients neovaginoplasty and vaginal mold spreaded with photoinduced-imine-crosslink hydrogel, neovaginoplasty and vaginal mold - Mayer Rokitansky Kuster Hauser Syndrome | Not applicable | Unknown | Obstetrics & Gynecology Hospital of Fudan University | 20 | 2024-08-01 | 2024-07-18 |
| Peritoneum Vaginoplasty; Implementation According to IDEAL Framework Laparoscopic pedicled single flap peritoneum vaginoplasty - Rokitansky Kuster Hauser Syndrome, Vaginal Neoplasms | Not applicable | Unknown | Amsterdam UMC, location VUmc | 13 | 2023-05-25 | 2023-06-29 |
| Evolution of the Quality of Life and Experience of Young Women With Utero-vaginal Aplasia (MRKHPSY) Questionnaires - Mrkh Syndrome | Completed | Assistance Publique - Hôpitaux de Paris | 25 | 2022-10-04 | 2025-11-20 | |
| Uterine Transplant for Women With Absolute Uterine Factor Infertility (AUFI) Uterine Transplant - Mayer Rokitansky Kuster Hauser Syndrome, Absence of Uterus | Not applicable | Recruiting | John Goss | 10 | 2022-06-03 | 2026-04-29 |
| Quality of Life and Sexual Function in Vaginal Aplasia Patients After Davydov Procedure Mayer Rokitansky Kuster Hauser Syndrome, Quality of Life | Completed | School of Medicine - Vietnam National University at Ho Chi Minh city | 29 | 2021-12-13 | 2022-11-18 | |
| Uterus Transplantation Procedure From a Live Donor Uterus transplantation - Rokitansky Kuster Hauser Syndrome, Sterility, Female | Not applicable | Unknown | Hospital Clinic of Barcelona | 10 | 2020-05-23 | 2020-11-10 |
| INvestigational Study Into Transplantation of the Uterus Mayer-Rokitansky-Kuster Syndrome, Asherson's Syndrome | Unknown | Womb Transplant UK | 10 | 2019-02-18 | 2020-01-28 | |
| Uterus Transplantation From Deceased Donor - Gothenburg III uterus transplantation - Absolute Uterine Factor Infertility, Transplantation | Not applicable | Completed | Sahlgrenska University Hospital | 1 | 2018-06-17 | 2024-06-21 |
| Uterus Transplantation LD - Feasibility Study - Sahlgrenska - BMC uterus transplantation surgery and IVF - Mrk Anomaly, Infertility, Female | Not applicable | Completed | Sahlgrenska University Hospital | 2 | 2018-06-15 | 2021-12-15 |
| The University of Pennsylvania Uterus Transplant for Uterine Factor Infertility Trial Uterine Transplant - Mayer Rokitansky Kuster Hauser Syndrome, Uterine Agenesis | Not applicable | Active not recruiting | University of Pennsylvania | 10 | 2018-01-10 | 2026-08-27 |
| Feasibility Study of Uterine Transplantation From Living Donors in Terms of Efficacy and Safety in Patients With Mayer-Rokitansky-Küster-Hauser Syndrome (MRKH) Uterine transplantation - Mayer Rokitansky Kuster Hauser Syndrome | Not applicable | Recruiting | Hopital Foch | 20 | 2017-12-14 | 2025-03-07 |
| Uterus Transplantation From a Multi-organ Donor uterus transplantation - Infertility, Female, Mayer Rokitansky Kuster Hauser Syndrome | Not applicable | Recruiting | University Hospital, Ghent | 20 | 2016-11-03 | 2024-02-14 |
| Molecular Genetic Study of Mayer-Rokitansky-Kuster-Hauser Syndrome Biological samples for patients, Biological samples for healthy relatives - Mayer Rokitansky Kuster Hauser Syndrome | Recruiting | Imagine Institute | 410 | 2016-05-01 | 2018-10-12 | |
| Uterine Transplantation and Pregnancy Induction in Women Affected by Absolute Uterine Infertility Uterine Transplant - Absolute Uterine Infertility | Not applicable | Active not recruiting | Baylor Research Institute | 38 | 2015-11-11 | 2026-03-23 |
| Uterus Transplantation From Live Donors and From Deceased Donors - Clinical Study Live donor uterus transplantation, Deceased donor uterus transplantation, Tacrolimus - Mayer Rokitansky Kuster Hauser Syndrome, Mullerian Aplasia | Phase 3 | Unknown | Institute for Clinical and Experimental Medicine | 20 | 2015-10-09 | 2019-02-27 |
| Assessment of Quality of Global and Sexual Life and Impact of Surgical and Non Surgical Vaginal Aplasia in Patients With a Rokitansky Syndrome evaluate quality of life of surgical and non surgical vaginal aplasia - Rokitansky Syndrome, Surgical or Vaginal Dilatation of Vaginal Aplasia | Not applicable | Completed | Assistance Publique - Hôpitaux de Paris | 138 | 2012-10-11 | 2025-09-05 |
| Urogynecological and Sexual Functions After Vecchietti Operation laparoscopic Vecchietti vaginoplasty, FSFI questionnaire, UDI-6 questionnaire - Mayer-Rokitansky-Kuster Syndrome | Completed | Medical University of Lublin | 26 | 2011-01-01 | 2019-01-18 |
Infertility (5) · Infertility, Female (4) · Gender Dysphoria (1) · Postpartum Hemorrhage (1) · Sexual Dysfunctions, Psychological (1) · Urinary Incontinence (1) · Uterine Cervical Neoplasms (1) · Vaginal Neoplasms (1)
Urogenital Diseases (10) · Genital Diseases (9) · Female Urogenital Diseases (7) · Female Urogenital Diseases and Pregnancy Complications (7) · Genital Diseases, Female (6) · Infertility (3) · Genital Neoplasms, Female (2) · Mental Disorders (2) · Neoplasms (2) · Neoplasms by Site (2) · Pathological Conditions, Signs and Symptoms (2) · Urogenital Neoplasms (2) · Hemorrhage (1) · Lower Urinary Tract Symptoms (1) · Male Urogenital Diseases (1)
Surveys and Questionnaires (2) · Cesarean Section (1) · Embryo Transfer (1) · Mycophenolic Acid (1) · Tacrolimus (1) · thymoglobulin (1)
Assistance Publique - Hôpitaux de Paris (2) · Obstetrics & Gynecology Hospital of Fudan University (2) · Sahlgrenska University Hospital (2) · Amsterdam UMC, location VUmc (1) · Baylor Research Institute (1) · Fondazione Policlinico Universitario Agostino Gemelli IRCCS (1) · Hopital Foch (1) · Hospital Clinic of Barcelona (1) · Imagine Institute (1) · Institute for Clinical and Experimental Medicine (1) · John Goss (1) · Medical University of Lublin (1) · School of Medicine - Vietnam National University at Ho Chi Minh city (1) · University Hospital, Ghent (1) · University Hospital, Toulouse (1)
France (5) · United States (3) · Sweden (2) · Belgium (1) · Czechia (1) · Italy (1) · Netherlands (1) · Spain (1) · United Kingdom (1) · Vietnam (1)
Keqin Hua, Doctor (2) · Antonia Carla Testa (1) · Francisco Carmona, MD, PhD (1) · Jiri Fronek, Assoc Prof (1) · John Goss, M.D. (1) · Karinne Gueniche, MD, PhD (1) · Kathleen E O'Neill, MD, MTR (1) · Lan TN Vuong, PhD (1) · Mark-Bram Bouman, MD PhD (1) · Michel Polak (1)
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