4 completed, 2 terminated, 2 unknown. 8 Phase 2, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 8 | Completed 4, Terminated 2, Unknown 2 |
| Phase 3 | 2 | Terminated 2 |
Follow Motion Sickness: new trials by email Literature Review of Motion Sickness trials Research Report on Motion Sickness
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Prevention of Post-Operative Nausea and Vomiting With Propofol Infusion Hybrid anesthesia (propofol + sevoflurane), Propofol only TIVA - Post-operative Nausea and Vomiting | Phase 2 | Completed | Milton S. Hershey Medical Center | 65 | 2024-02-01 | 2026-08-14 |
| Combination of Intranasal Scopolamine and Sensory Augmentation to Mitigate G-transition Induced Motion Sickness and Enhance Sensorimotor Performance DPI-386 Nasal Gel, Placebo Nasal Gel - Motion Sickness, Space, Motion Sickness | Phase 2 | Unknown | Repurposed Therapeutics, Inc. | 30 | 2022-01-21 | 2024-05-17 |
| Combination of Intranasal Scopolamine and Sensory Augmentation to Mitigate G-transition Induced Motion Sickness and Enhance Sensorimotor Performance DPI-386 Nasal Gel, Other (e.g., promethazine, meclizine) - Motion Sickness, Space, Motion Simulation | Phase 2 | Unknown | Repurposed Therapeutics, Inc. | 80 | 2021-08-10 | 2024-05-16 |
| Motion Sifnos: A Study to Investigate the Efficacy of Tradipitant in Subjects Affected by Motion Sickness Tradipitant, Placebo - Motion Sickness | Phase 2 | Completed | Vanda Pharmaceuticals | 126 | 2018-12-20 | 2025-05-09 |
| DPI 386 Nasal Gel for the Prevention of Nausea Associated With Motion Sickness DPI-386 Nasal Gel, DPI-386 Placebo Nasal Gel, Transderm ScopĀ® - Motion Sickness | Phase 2 / Phase 3 | Terminated | Repurposed Therapeutics, Inc. | 23 | 2018-06-29 | 2020-01-07 |
| Levo Phencynonate Hydrochloride for the Prevention of Seasickness placebo, levo phencynonate hydrochloride - Motion Sickness | Phase 2 | Completed | Sihuan Pharmaceutical Holdings Group Ltd. | 180 | 2014-08-01 | 2015-05-07 |
| Pharmacokinetic and Efficacy Profile Intranasal Scopolamine Spray Scopolamine, Placebo - Motion Sickness | Phase 2 / Phase 3 | Terminated | Repurposed Therapeutics, Inc. | 63 | 2014-06-01 | 2018-01-17 |
| Effects of Transdermal Scopolamine on Occupational Performance Scopolamine - Motion Sickness | Phase 2 | Completed | Boston University | 33 | 2005-04-01 | 2007-04-09 |
Space Motion Sickness (2) · Vomiting (1)
Pathological Conditions, Signs and Symptoms (8) · Signs and Symptoms (8) · Signs and Symptoms, Digestive (1)
Scopolamine (5) · Meclizine (1) · Promethazine (1) · Propofol (1) · Sevoflurane (1)
Repurposed Therapeutics, Inc. (4) · Boston University (1) · Milton S. Hershey Medical Center (1) · Sihuan Pharmaceutical Holdings Group Ltd. (1) · Vanda Pharmaceuticals (1)
United States (6) · China (1) · Sweden (1)
Scott J Wood, PhD (2) · David Helton (1) · Jonathan Howland, Ph.D., MPH (1) · Sonal Sharma, MD (1) · Weiguo Xue (1) · Willliam J Becker, Phd (1)