11 completed, 1 recruiting. 6 Phase 3, 5 Phase 2, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 6 | Completed 6 |
| Phase 2 | 5 | Completed 5 |
| Phase 1 | 2 | Completed 1, Recruiting 1 |
Follow Moderate or Severe Submental Fullness: new trials by email Literature Review of Moderate or Severe Submental Fullness trials Research Report on Moderate or Severe Submental Fullness
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Phase I Study of HY-2003 in the Subjects With Excessive Submental Fat Accumulation HY-2003 (10 mg/ml), BELKYRA and placebo, HY-2003 (5 mg/ml) and placebo - Moderate or Severe Submental Fullness | Phase 1 | Recruiting | Sichuan Huiyu Pharmaceutical Co., Ltd | 30 | 2024-12-26 | 2026-03-09 |
| Determine the Dosing Interval and Optimal Dose of AYP-101 for the Reduction of Submental Fat in Chin Area Polyene Phosphatidylcholine, Placebo - Moderate or Severe Submental Fullness | Phase 2 | Completed | AMIpharm Co., Ltd. | 96 | 2022-03-02 | 2023-08-15 |
| Evaluate the Efficacy and Safety of Polyene Phosphatidylcholine Injection (AYP-101) for the Reduction of Submental Fat Polyene phosphatidylcholine injection, Placebo - Moderate or Severe Submental Fullness | Phase 2 | Completed | AMIpharm Co., Ltd. | 143 | 2019-07-01 | 2023-08-15 |
| Patient Experience Study of Deoxycholic Acid Injection Deoxycholic Acid Injection, Placebo, Cold Compress - Moderate or Severe Submental Fullness | Phase 3 | Completed | Kythera Biopharmaceuticals | 84 | 2013-12-01 | 2015-07-28 |
| Phase 3 Study of Deoxycholic Acid Injection (ATX-101) Versus Placebo for the Reduction of Localized Subcutaneous Fat in the Submental Area Deoxycholic acid injection, Placebo - Moderate or Severe Submental Fullness | Phase 3 | Completed | Kythera Biopharmaceuticals | 516 | 2012-03-01 | 2015-06-15 |
| Phase 3 Study of Deoxycholic Acid Injection (ATX-101) Versus Placebo for the Reduction of Localized Subcutaneous Fat in the Submental Area Deoxycholic acid injection, Placebo - Moderate or Severe Submental Fullness | Phase 3 | Completed | Kythera Biopharmaceuticals | 506 | 2012-02-01 | 2015-06-15 |
| Open-Label Study of Deoxycholic Acid for the Reduction of Localized Subcutaneous Fat in the Submental Area Deoxycholic acid injection - Moderate or Severe Submental Fullness | Phase 3 | Completed | Kythera Biopharmaceuticals | 165 | 2011-08-01 | 2016-01-14 |
| Evaluation of Safety and Efficacy of Deoxycholic Acid Injection (ATX-101) in the Reduction of Submental Fat Deoxycholic acid injection, Placebo - Moderate or Severe Submental Fullness | Phase 3 | Completed | Kythera Biopharmaceuticals | 360 | 2011-01-01 | 2015-06-12 |
| Evaluation of Safety and Efficacy of Deoxycholic Acid Injection (ATX-101) in the Reduction of Submental Fat Deoxycholic acid injection, Placebo - Moderate or Severe Submental Fullness | Phase 3 | Completed | Kythera Biopharmaceuticals | 363 | 2010-12-01 | 2015-07-14 |
| Deoxycholic Acid Injection Submental Fat (SMF) Magnetic Resonance Imaging (MRI) and Subject-reported Outcome Measures Study Deoxycholic acid injection, Placebo - Moderate or Severe Submental Fullness | Phase 2 | Completed | Kythera Biopharmaceuticals | 129 | 2009-12-01 | 2015-06-15 |
| Phase 2 Study of Deoxycholic Acid Injection (ATX-101) for the Reduction of Submental Fat Deoxycholic Acid Injection, Placebo - Moderate or Severe Submental Fullness | Phase 2 | Completed | Kythera Biopharmaceuticals | 73 | 2008-04-01 | 2015-07-14 |
| Phase 1-2 Study of Deoxycholic Acid Injection (ATX-101) for the Reduction of Submental Fat Deoxycholic Acid Injection, Placebo - Moderate or Severe Submental Fullness | Phase 1 / Phase 2 | Completed | Kythera Biopharmaceuticals | 85 | 2007-08-01 | 2015-07-14 |
Lymphoma, Follicular (12)
Hemic and Lymphatic Diseases (12) · Immune System Diseases (12) · Immunoproliferative Disorders (12) · Lymphatic Diseases (12) · Lymphoma (12) · Lymphoma, Non-Hodgkin (12) · Lymphoproliferative Disorders (12) · Neoplasms (12) · Neoplasms by Histologic Type (12)
Deoxycholic Acid (9) · polyene phosphatidylcholine (2) · Epinephrine (1) · Ibuprofen (1) · Lidocaine (1) · Loratadine (1)
Kythera Biopharmaceuticals (9) · AMIpharm Co., Ltd. (2) · Sichuan Huiyu Pharmaceutical Co., Ltd (1)
United States (5) · Canada (4) · United Kingdom (4) · Australia (2) · Belgium (2) · France (2) · Germany (2) · South Korea (2) · Spain (2) · China (1) · Italy (1)
Frederick Beddingfield, MD, PhD (5) · Dae Hyeon Lew, MD,PhD (1) · Frederick Beddingfield, III, M.D., Ph.D. (1) · Frederick Beddingfield, III, M.D., PhD (1) · Frederick Beddingfield, III, MD, PhD (1) · Frederick Beddingfield, MD. PhD (1)