7 completed, 2 active not recruiting, 1 unknown. 3 Not applicable, 1 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 3 | Completed 3 |
| Phase 1 | 1 | Completed 1 |
| Phase 2 | 1 | Completed 1 |
Follow McArdle Disease: new trials by email Literature Review of McArdle Disease trials Research Report on McArdle Disease
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Novel Metabolic Muscular Biomarkers in Pompe Disease - a Non-invasive Magnetic Resonance Exploratory Pilot Study. Siemens Magnetom 7T Plus - Pompe Disease, McArdle Disease | Active not recruiting | Medical University of Vienna | 30 | 2023-08-15 | 2025-08-26 | |
| Carbon-13 Magnetic Resonance Spectroscopy in Glycogen Storage Diseases No intervention - Glycogen Storage Disease, McArdle Disease | Active not recruiting | Copenhagen University Hospital, Rigshospitalet | 50 | 2021-12-10 | 2025-08-11 | |
| Ketogenic Diet Survey in Patients With McArdle Disease (GSDV) There is no intervention, as this is a survey study - McArdle Disease | Completed | Nicoline Løkken | 200 | 2021-01-10 | 2023-02-13 | |
| Fast Troponin as a Biomarker to Assess Exercise-induced Muscle Damage in Muscle Diseases Becker Muscular Dystrophy, McArdle Disease | Completed | Mads Peter Godtfeldt Stemmerik | 36 | 2020-06-01 | 2022-10-27 | |
| A Study of the Safety of REN001 in Patients With McArdle Disease REN001 - McArdle Disease | Phase 1 | Completed | Reneo Pharma Ltd | 19 | 2019-12-10 | 2022-01-12 |
| Modified Ketogenic Diet in Patients With McArdle Disease Part B Ketocal 4:1 liquid Nutricia (intervention), Fortini multifibre Nutrica (placebo) - McArdle Disease | Not applicable | Completed | Copenhagen University Hospital, Rigshospitalet | 20 | 2019-08-03 | 2023-02-13 |
| Oral Ketone Body Supplementation in Patients With McArdle Disease β-hydroxybuturate esters, Placebo drink - McArdle Disease | Not applicable | Completed | Copenhagen University Hospital, Rigshospitalet | 8 | 2019-05-06 | 2020-10-06 |
| Modified Ketogenic Diet in Patients With McArdle Disease Part A Modified ketogenic diets - McArdle Disease | Not applicable | Completed | Copenhagen University Hospital, Rigshospitalet | 11 | 2019-02-16 | 2019-05-10 |
| Muscle Relaxation in Myopathies With Positive Muscle Phenomena Transcranial magnetic stimulation (TMS) - Nemaline Myopathy Type 6, Myotonic Dystrophy Type 2 | Unknown | Radboud University Medical Center | 30 | 2017-01-05 | 2019-10-01 | |
| Sodium Valproate for GSDV Sodium Valproate - Glycogen Storage Disease Type V, McArdle Disease | Phase 2 | Completed | University College, London | 8 | 2015-01-01 | 2018-02-05 |
Glycogen Storage Disease Type V (10) · Glycogen Storage Disease (2) · Glycogen Storage Disease Type II (2) · Limb-girdle muscular dystrophy type 2A (1) · Muscular Diseases (1) · Muscular Dystrophy, Duchenne (1) · Myotonic Dystrophy (1)
Carbohydrate Metabolism, Inborn Errors (10) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (10) · Genetic Diseases, Inborn (10) · Metabolic Diseases (10) · Metabolism, Inborn Errors (10) · Nutritional and Metabolic Diseases (10) · Glycogen Storage Disease (8) · Nervous System Diseases (4) · Brain Diseases (2) · Brain Diseases, Metabolic (2) · Brain Diseases, Metabolic, Inborn (2) · Central Nervous System Diseases (2) · Lysosomal Storage Diseases (2) · Lysosomal Storage Diseases, Nervous System (2) · Muscular Disorders, Atrophic (2)
Methods (1) · Valproic Acid (1)
Copenhagen University Hospital, Rigshospitalet (4) · Mads Peter Godtfeldt Stemmerik (1) · Medical University of Vienna (1) · Nicoline Løkken (1) · Radboud University Medical Center (1) · Reneo Pharma Ltd (1) · University College, London (1)
Denmark (7) · United Kingdom (3) · Austria (1) · Spain (1)
Baziel G van Engelen, MD, PhD (1) · Ros Quinlivan, FRCPCH, MD (1) · Rosaline Quinlivan, MD (1)