29 completed, 21 recruiting, 10 active not recruiting, 9 unknown. 38 Phase 2, 21 Phase 1, 9 Not applicable, 4 Phase 3, 3 Phase 4.
Follow Lymphoblastic Lymphoma: new trials by email Literature Review of Lymphoblastic Lymphoma trials Research Report on Lymphoblastic Lymphoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Depletion of CD45RA Positive Naive T Cells for the Prevention of Graft Versus Host Disease in Older Patients Undergoing Allogeneic Hematopoietic Cell Transplantation for Acute Leukemia or Myelodysplastic Syndrome Allogeneic CD34+-enriched and CD45RA-depleted PBSCs, Biospecimen Collection, Bone Marrow Aspiration - Acute Biphenotypic Leukemia, Acute Leukemia | Phase 2 | Not yet recruiting | Fred Hutchinson Cancer Center | 52 | 2027-01-01 | 2026-09-14 |
| First-in-human Study of a New Treatment (4A10) for Patients With Relapsed or Hard-to-treat Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma, Focused on Safety and How the Drug Behaves in the Body and Early Signs of Effect. 4A10 - Lymphoblastic Lymphoma, Acute Lymphoblastic Leukemia ALL | Phase 1 | Recruiting | Allterum Therapeutics, Inc | 24 | 2026-06-01 | 2026-09-01 |
| A Vaccine (CMV-MVA Triplex Vaccine) for the Enhancement of CMV-Specific Immunity and the Prevention of CMV Viremia in Patients Undergoing Haploidentical Hematopoietic Stem Cell Transplant Biospecimen Collection, Electronic Health Record Review, Haploidentical Hematopoietic Cell Transplantation - Accelerated Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive, Acute Lymphoblastic Leukemia | Phase 1 | Recruiting | City of Hope Medical Center | 46 | 2026-05-08 | 2026-07-28 |
| Strength Training Exercise in Pediatric Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma (STEP-ALL) Exercises - Leukemia, Acute Leukemia | Not applicable | Recruiting | UNC Lineberger Comprehensive Cancer Center | 40 | 2026-05-01 | 2026-08-03 |
| Dose-Adjusted EPOCH With or Without Rituximab Plus Ponatinib for the Treatment of Newly-Diagnosed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia/Lymphoma Cyclophosphamide, Doxorubicin, Etoposide - B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1, B Lymphoblastic Leukemia/Lymphoma With t(9;22)(q34.1;q11.2); BCR-ABL1 | Phase 2 | Recruiting | University of Washington | 33 | 2026-03-30 | 2026-08-13 |
| Asparaginase Erwinia Chrysanthemi With Chemotherapy for the Treatment of High-Risk Adults With Newly Diagnosed Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma Asparaginase Erwinia chrysanthemi, Biospecimen Collection, Bone Marrow Aspiration - B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative, Lymphoblastic Lymphoma | Phase 2 | Recruiting | City of Hope Medical Center | 53 | 2025-10-10 | 2026-10-13 |
| Mobile Health Intervention to Support Oral Chemotherapy Adherence in Adolescents and Young Adults With Leukemia ADAPTS (ADherence Assessments and Personalized Timely Support). - Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma | Not applicable | Recruiting | Northwestern University | 60 | 2025-07-31 | 2026-06-30 |
| CAYA Cancer Retrospective Cohort Study Retrospective Medical Record Review - Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma | Recruiting | Resonance, Inc. | 18000 | 2025-06-04 | 2026-09-29 | |
| A Phase 2 Study of WU-CART-007, an Anti-CD7 Allogeneic CAR-T Cell Therapy in T-Cell Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma (T-RRex) WU-CART-007 - T-cell Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma | Phase 2 | Recruiting | Allotera Therapeutics | 125 | 2025-01-31 | 2026-09-28 |
| Therapy for Newly Diagnosed Patients With B-Cell Precursor Acute Lymphoblastic Leukemia and Lymphoma Dexamethasone, Vincristine, Inotuzumab - Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma | Phase 2 | Recruiting | St. Jude Children's Research Hospital | 128 | 2025-01-23 | 2026-07-16 |
| Identification of Necessary Information for Treatment Induction in Newly Diagnosed Acute Lymphoblastic Leukemia/Lymphoma Dexamethasone, Vincristine, Daunorubicin - Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma | Phase 4 | Recruiting | St. Jude Children's Research Hospital | 850 | 2024-12-26 | 2026-07-14 |
| A Study to Investigate LP-118, Ponatinib, Vincristine and Dexamethasone in Relapsed/Refractory Acute Lymphoblastic Leukemia (ALL) or Lymphoblastic Lymphoma (LBL) LP-118, Ponatinib, Vincristine - Acute Leukemia, Lymphoblastic Leukemia | Phase 1 / Phase 2 | Recruiting | University of Chicago | 15 | 2024-09-13 | 2026-03-18 |
| Anti-CD19 Chimeric Antigen Receptor T-Cell Immunotherapy for Leukemias Autologous HuCD19 ( Anti-CD19)CAR T cells, Cyclophosphamide, Fludarabine - Leukemia, Lymphocytic, Chronic, B-Cell, B-Lymphocytic Leukemia, Chronic | Phase 1 / Phase 2 | Recruiting | National Cancer Institute (NCI) | 132 | 2024-09-03 | 2026-10-16 |
| BeFluBu vs FluBuRux Conditioning in Haploidentical HCT Bendamustine Hydrochloride, Ruxolitinib - Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia | Phase 2 | Recruiting | St. Petersburg State Pavlov Medical University | 220 | 2024-06-21 | 2024-06-27 |
| Vitamin A and D Supplementation in Allogeneic HCT Vitamin A, Vitamin D3 - Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia | Phase 2 | Recruiting | St. Petersburg State Pavlov Medical University | 220 | 2024-05-15 | 2024-07-31 |
| A Study of PD5K3 in Healthy Adult Volunteers PD5K3, Placebo, Pegaspargase - Lymphoblastic Leukemia, Acute, Lymphoblastic Lymphoma | Phase 1 | Completed | Chongqing Peg-Bio Biopharm Co., Ltd. | 28 | 2023-11-27 | 2024-07-30 |
| Studying the Effect of Levocarnitine in Protecting the Liver From Chemotherapy for Leukemia or Lymphoma Biospecimen Collection, Calaspargase Pegol, Levocarnitine - B Acute Lymphoblastic Leukemia, B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1 | Phase 3 | Active not recruiting | Children's Oncology Group | 440 | 2023-08-24 | 2026-08-21 |
| A Study Evaluating the Safety and Efficacy of BEAM-201 in Relapsed/Refractory T-Cell Acute Lymphoblastic Leukemia (T-ALL) or T-Cell Lymphoblastic Lymphoma (T-LL) BEAM-201 - Lymphoblastic Lymphoma, T-Cell Lymphoblastic Leukemia/Lymphoma | Phase 1 / Phase 2 | Active not recruiting | Beam Therapeutics Inc. | 5 | 2023-05-25 | 2025-01-13 |
| MT2021-08T Cell Receptor Alpha/Beta Depletion PBSC Transplantation for Heme Malignancies Fludarabine, Busulfan, Melphalan - Hematologic Malignancy, Acute Leukemia | Phase 2 | Recruiting | Masonic Cancer Center, University of Minnesota | 70 | 2023-05-11 | 2026-04-06 |
| MCW Alpha/Beta T-Cell and B-Cell Depletion With Targeted ATG Dosing Magnetic-Activated Cell Sorter (CliniMACS, Miltenyi) - Leukemia, Acute Myeloid Leukemia in Remission | Not applicable | Recruiting | Medical College of Wisconsin | 40 | 2023-05-01 | 2026-05-13 |
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Precursor Cell Lymphoblastic Leukemia-Lymphoma (80) · Leukemia, Myeloid, Acute (22) · Burkitt Lymphoma (21) · Myelodysplastic Syndromes (15) · Leukemia, Biphenotypic, Acute (13) · Leukemia, Lymphocytic, Chronic, B-Cell (13) · Leukemia (12) · Lymphoma (11) · Leukemia, Myelogenous, Chronic, BCR-ABL Positive (10) · Lymphoma, Non-Hodgkin (10) · Myeloproliferative Disorders (10) · Hodgkin Disease (8) · Lymphoma, Mantle-Cell (8) · Primary Myelofibrosis (8) · Leukemia, Myeloid, Chronic-Phase (7)
Hemic and Lymphatic Diseases (80) · Immune System Diseases (80) · Immunoproliferative Disorders (80) · Lymphatic Diseases (80) · Lymphoproliferative Disorders (80) · Neoplasms by Histologic Type (80) · Hematologic Diseases (79) · Leukemia, Lymphoid (79) · Neoplasms (76) · Leukemia (68) · Lymphoma (29) · Pathological Conditions, Signs and Symptoms (27) · Pathologic Processes (26) · Leukemia, Myeloid (25) · Bone Marrow Diseases (24)
Cyclophosphamide (31) · Methotrexate (23) · Vincristine (21) · Cytarabine (19) · Dexamethasone (13) · Doxorubicin (13) · fludarabine (12) · Etoposide (11) · Mercaptopurine (11) · pegaspargase (11) · Daunorubicin (10) · Calcium Dobesilate (9) · Rituximab (9) · Whole-Body Irradiation (9) · Prednisone (8)
City of Hope Medical Center (7) · Fred Hutchinson Cancer Center (5) · M.D. Anderson Cancer Center (5) · Masonic Cancer Center, University of Minnesota (5) · St. Jude Children's Research Hospital (4) · Children's Oncology Group (3) · Jazz Pharmaceuticals (3) · St. Petersburg State Pavlov Medical University (3) · AbbVie (2) · Allotera Therapeutics (2) · Dana-Farber Cancer Institute (2) · New York Medical College (2) · Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine (2) · Therapeutic Advances in Childhood Leukemia Consortium (2) · University of Washington (2)
United States (59) · Australia (6) · Canada (5) · China (5) · Germany (3) · Russia (3) · France (2) · Italy (2) · South Korea (2) · Armenia (1) · Belgium (1) · Denmark (1) · Egypt (1) · El Salvador (1) · Guatemala (1)
Cherry Thomas, MD (2) · Marie Bleakley (2) · Phuong Vo, MD (2) · Ryotaro Nakamura (2) · Adam Lamble, MD (1) · Alexandra M Psihogios, Ph.D. (1) · Alicia Kunin-Batson, Ph.D. (1) · Andrew Place, MD (1) · Ann E. Dahlberg (1) · Ann Jakubowski, MD (1) · Claudio Brunstein, MD (1) · Claudio Brunstein, MD, PhD (1) · Dae-Young Kim, MD, PhD (1) · Elias Jabbour (1)
PMID 22677206, PMID 10627444, PMID 11863096, PMID 14585365, PMID 16421426, PMID 17003366, PMID 17410187, PMID 18626005, PMID 19167677, PMID 19433688, PMID 23383989, PMID 23389497, PMID 24344215, PMID 25359988, PMID 26014292, PMID 26230956, PMID 26376459, PMID 26887549, PMID 27760761, PMID 32040960, PMID 32589978, PMID 33026184, PMID 33049057, PMID 34138471, PMID 34228505, PMID 34644414, PMID 34810210, PMID 35007144, PMID 35478711, PMID 35622074, PMID 36053823, PMID 36625831, PMID 36669148, PMID 36936918, PMID 37553297, PMID 39149468, PMID 39368878, PMID 40445850, PMID 40641817, PMID 41671463, PMID 42477805, PMID 42561216, PMID 42720434, PMID 7581076
P30CA033572 (4), P01CA018029 (2), P30CA015704 (2), UG1CA189955 (2), R01CA077544 (1), R01CA211996 (1), R01HL121568 (1), R35CA210084 (1), R44CA268530 (1), U10CA095861 (1), U24CA196173 (1)