4 recruiting, 2 unknown, 1 completed. 4 Phase 1, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 4 | Recruiting 2, Unknown 2 |
| Phase 2 | 3 | Recruiting 2, Unknown 1 |
Follow Lymphoblastic Leukemia in Children: new trials by email Literature Review of Lymphoblastic Leukemia in Children trials Research Report on Lymphoblastic Leukemia in Children
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Prospective Trial of Dalbavancin-Based Prophylaxis in Children and Adolescents With High-Risk Leukemia Dalbavancin, Fluoroquinolone (either ciprofloxacin or levofloxacin at the discretion of the treating clinician) - Leukemia, Acute Myeloid Leukemia | Phase 1 | Recruiting | St. Jude Children's Research Hospital | 29 | 2025-05-22 | 2026-09-15 |
| Treatment of Newly Diagnosed Standard Risk Acute Lymphoblastic Leukemia in Children induction: vincristine, L-asparaginase, dexamethasone, intrathecal Ara-C, intrathecal Methotrexate, Consolidation: Vincristine, Mecaptopurine, Intrathecal Methotrexate, Consolidation: Vincristine, Mecaptopurine, Cyclophosphamide, Cytarabine, L-asparaginase, Intrathecal Methotrexate - Lymphoblastic Leukemia in Children | Phase 2 | Recruiting | Hee Young Ju | 116 | 2024-03-05 | 2026-07-29 |
| Dual Anti-CD22/CD19 Chimeric Antigen Receptor-directed T Cells (CART2219.1) for Relapsed Refractory B-Lineage Leukaemia Phase I, Phase II - Lymphoblastic Leukemia, Lymphoblastic Leukemia, Acute, Childhood | Phase 1 / Phase 2 | Unknown | KK Women's and Children's Hospital | 48 | 2022-07-18 | 2023-03-09 |
| CD19-Directed Chimeric Antigen Receptor (CAR) T-Cell Therapy for Relapsed/Refractory B-Lineage Leukaemia / Lymphoma - A Feasibility Protocol Anti-CD19 CAR T-cells - Lymphoblastic Leukemia, Lymphoblastic Leukemia in Children | Phase 2 | Recruiting | KK Women's and Children's Hospital | 40 | 2022-03-15 | 2023-03-09 |
| CARTALL: Chimeric-Antigen Receptor (CAR) T-Cell Therapy for Relapsed/ Refractory T-Lineage Acute Lymphoblastic Leukaemia CAR T-cell therapy - Lymphoblastic Leukemia, Acute, Childhood, Lymphoblastic Leukemia | Phase 1 | Recruiting | National University Hospital, Singapore | 20 | 2021-09-08 | 2021-09-14 |
| ALaCART-B: Acute Leukemia and Chimeric Antigen Receptor-T Cell Therapy for B-lymphoblastic Leukemia. CAR T-cell therapy - Lymphoblastic Leukemia, Acute, Childhood, Lymphoblastic Leukemia | Phase 1 | Unknown | National University Hospital, Singapore | 40 | 2021-04-28 | 2021-09-09 |
| Association Between Mitochondrial DNA Content and Risk of Acute Leukemia Relative copy number of mitochondrial DNA - Lymphoblastic Leukemia in Children | Completed | Air Force Military Medical University, China | 300 | 2018-11-01 | 2020-07-10 |
Precursor Cell Lymphoblastic Leukemia-Lymphoma (4) · Leukemia (2) · Burkitt Lymphoma (1) · Leukemia, Myeloid, Acute (1) · Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (1) · Recurrence (1)
Hematologic Diseases (5) · Hemic and Lymphatic Diseases (5) · Neoplasms (5) · Neoplasms by Histologic Type (5) · Immune System Diseases (4) · Immunoproliferative Disorders (4) · Leukemia, Lymphoid (4) · Lymphatic Diseases (4) · Lymphoproliferative Disorders (4) · Leukemia (3) · DNA Virus Infections (1) · Disease Attributes (1) · Epstein-Barr Virus Infections (1) · Herpesviridae Infections (1) · Infections (1)
Immunotherapy, Adoptive (2) · Asparaginase (1) · Clinical Trials, Phase I as Topic (1) · Clinical Trials, Phase II as Topic (1) · Cyclophosphamide (1) · Cytarabine (1) · Dexamethasone (1) · Doxorubicin (1) · Fluoroquinolones (1) · Mercaptopurine (1) · Methotrexate (1) · dalbavancin (1)
KK Women's and Children's Hospital (2) · National University Hospital, Singapore (2) · Air Force Military Medical University, China (1) · Hee Young Ju (1) · St. Jude Children's Research Hospital (1)
Singapore (4) · China (1) · South Korea (1) · United States (1)
Allen Yeoh, M.D (2) · Dario Campana, M.D, PhD (2) · Aloysius Ho, MD (1) · Joshua Wolf, MBBS (1) · Michaela Seng, MD (1) · Shui Yen Soh, MD (1) · Wing Hang Leung, MD PhD (1)