2 completed, 1 active not recruiting. 3 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 3 | Completed 2, Active not recruiting 1 |
Follow Lymphangiomyoma: new trials by email Literature Review of Lymphangiomyoma trials Research Report on Lymphangiomyoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Multicenter Interventional Lymphangioleiomyomatosis (LAM) Early Disease Trial Sirolimus - LAM, Lymphangioleiomyomatosis | Phase 3 | Active not recruiting | University of Cincinnati | 60 | 2018-01-01 | 2024-12-24 |
| Efficacy and Safety of RAD001 in Patients Aged 18 and Over With Angiomyolipoma Associated With Either Tuberous Sclerosis Complex (TSC) or Sporadic Lymphangioleiomyomatosis (LAM) Everolimus (RAD001), Everolimus Placebo - Tuberous Sclerosis Complex (TSC), Lymphangioleiomyomatosis (LAM) | Phase 3 | Completed | Novartis Pharmaceuticals | 118 | 2009-04-01 | 2017-02-17 |
| Efficacy and Safety of Sirolimus in LAM Sirolimus, Placebo - Lymphangioleiomyomatosis | Phase 3 | Completed | University of Cincinnati | 89 | 2006-12-01 | 2023-11-02 |
Lymphangioleiomyomatosis (3) · Angiomyolipoma (1) · Astrocytoma (1) · Hereditary Sensory and Autonomic Neuropathies (1) · Seizures (1) · Tuberous Sclerosis (1) · Tuberous Sclerosis 2 (1)
Hemic and Lymphatic Diseases (3) · Immune System Diseases (3) · Immunoproliferative Disorders (3) · Lymphatic Diseases (3) · Lymphoproliferative Disorders (3) · Neoplasm, Lymphatic Tissue (3) · Neoplasms (3) · Neoplasms by Histologic Type (3) · Neoplasms, Connective and Soft Tissue (3) · Perivascular Epithelioid Cell Neoplasms (3) · Congenital Abnormalities (1) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (1) · Genetic Diseases, Inborn (1) · Glioma (1)
Sirolimus (2) · Everolimus (1)
University of Cincinnati (2) · Novartis Pharmaceuticals (1)
United States (3) · Canada (2) · Japan (2) · France (1) · Germany (1) · Italy (1) · Netherlands (1) · Poland (1) · Russia (1) · Spain (1) · United Kingdom (1)
Francis X McCormack, MD (1) · Francis X. McCormack, M.D. (1)
PMID 21180274, PMID 21410393, PMID 24159565, PMID 25979023, PMID 26156073, PMID 26799509, PMID 29023494, PMID 30053159, PMID 30192751, PMID 30846465, PMID 36927115
2008 (1), U01HL131755 (1), U54RR019498 (1)