4 recruiting, 2 completed, 1 active not recruiting, 1 not yet recruiting. 6 Phase 2, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 6 | Recruiting 2, Active not recruiting 1, Completed 1, Not yet recruiting 1, Suspended 1 |
| Phase 4 | 1 | Completed 1 |
Follow Locally Advanced Basal Cell Carcinoma: new trials by email Literature Review of Locally Advanced Basal Cell Carcinoma trials Research Report on Locally Advanced Basal Cell Carcinoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study Comparing Cemiplimab-based Treatments for Adult Participants With Locally Advanced Basal Cell Skin Cancer (laBCC) Cemiplimab, Vidutolimod, Fianlimab - Locally Advanced Basal Cell Carcinoma | Phase 2 | Not yet recruiting | Regeneron Pharmaceuticals | 135 | 2026-10-15 | 2026-09-09 |
| L19IL2/TNF in Patients With Basal Cell Carcinoma L19IL2/L19TNF - Locally Advanced Basal Cell Carcinoma | Phase 2 | Recruiting | Philogen S.p.A. | 92 | 2026-09-01 | 2026-07-21 |
| L19IL2 or L19TNF or L19IL2/TNF in Patients With Basal Cell Carcinoma (BCC) L19IL2, L19TNF, L19IL2/L19TNF - Locally Advanced Basal Cell Carcinoma | Phase 2 | Recruiting | Philogen S.p.A. | 180 | 2026-06-01 | 2026-07-31 |
| Studying Off Label Insurance Coverage for Patients With Cutaneous Cancers a "Filter" Observational Study Non-Interventional Study - Clinical Stage II Cutaneous Merkel Cell Carcinoma AJCC v8, Clinical Stage III Cutaneous Merkel Cell Carcinoma AJCC v8 | Recruiting | Ohio State University Comprehensive Cancer Center | 70 | 2026-02-04 | 2026-06-25 | |
| Cemiplimab Plus Fianlimab for the Treatment of Locally Advanced Head and Neck Basal Cell Carcinoma Before Surgery Cemiplimab, Computed Tomography, Biospecimen Collection - Locally Advanced Basal Cell Carcinoma, Basal Cell Carcinoma | Phase 2 | Suspended | Thomas Jefferson University | 70 | 2023-07-05 | 2026-06-10 |
| Oral Hedgehog Inhibitors in the Treatment of Basal Cell Carcinoma in the Netherlands: a Prospective Registration Study Vismodegib, Sonidegib - Basal Cell Carcinoma, Locally Advanced Basal Cell Carcinoma | Recruiting | Maastricht University Medical Center | 80 | 2021-11-01 | 2025-04-04 | |
| Tailored Sonidegib Schedule After Complete Response in BCC Sonidegib - Locally Advanced Basal Cell Carcinoma | Phase 2 | Active not recruiting | Gruppo Oncologico del Nord-Ovest | 21 | 2021-01-12 | 2026-06-01 |
| Relationship Between Pharmacokinetics and Safety of Vismodegib - OPTIVISMO-1 Treatment with vismodegib - Metastatic Basal Cell Carcinoma, Locally Advanced Basal Cell Carcinoma | Phase 4 | Completed | University Hospital, Bordeaux | 27 | 2018-09-03 | 2026-05-19 |
| Phase II Study of Radiation Therapy and Vismodegib for Advanced Head/Neck Basal Cell Carcinoma Vismodegib, Radiation therapy - Locally Advanced Basal Cell Carcinoma, Skin Cancer | Phase 2 | Completed | Sue Yom | 24 | 2013-05-01 | 2021-05-03 |
Carcinoma, Basal Cell (6) · Skin Neoplasms (3) · Basal Cell Nevus Syndrome (1) · Carcinoma (1) · Head and Neck Neoplasms (1) · Neoplasms, Basal Cell (1)
Neoplasms (7) · Neoplasms by Histologic Type (6) · Neoplasms, Glandular and Epithelial (6) · Carcinoma (5) · Neoplasms, Basal Cell (5) · Neoplasms by Site (3) · Skin Diseases (3) · Skin and Connective Tissue Diseases (3) · Abnormalities, Multiple (1) · Bone Cysts (1) · Bone Diseases (1) · Bone Diseases, Developmental (1) · Congenital Abnormalities (1) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (1) · Cysts (1)
HhAntag691 (3) · cemiplimab (2) · daromun (2) · sonidegib (2) · Biopsy (1) · Disulfides (1) · Immunoglobulin G (1) · Magnetic Resonance Spectroscopy (1) · Radiotherapy (1) · Specimen Handling (1) · Therapeutics (1) · X-Rays (1)
Philogen S.p.A. (2) · Gruppo Oncologico del Nord-Ovest (1) · Maastricht University Medical Center (1) · Ohio State University Comprehensive Cancer Center (1) · Regeneron Pharmaceuticals (1) · Sue Yom (1) · Thomas Jefferson University (1) · University Hospital, Bordeaux (1)
United States (5) · Italy (3) · Germany (2) · Greece (2) · Spain (2) · France (1) · Netherlands (1)
Claire F Verschraegen, MD (1) · Joseph Curry, MD (1) · K Mosterd, MD, PhD (1) · Paolo Bossi, MD (1) · Sue Yom, MD (1)
2025 (2)