4 completed, 1 recruiting, 1 unknown, 1 withdrawn. 1 Not applicable, 1 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 1 | Recruiting 1 |
| Phase 2 | 1 | Completed 1 |
| Phase 3 | 1 | Completed 1 |
Follow Lipoprotein Lipase Deficiency: new trials by email Literature Review of Lipoprotein Lipase Deficiency trials Research Report on Lipoprotein Lipase Deficiency
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Postprandial Fatty Acid Metabolism in Subjects With Lipoprotein Lipase Deficiency Heparin, liquid meal - Lipoprotein Lipase Deficiency | Not applicable | Recruiting | Université de Sherbrooke | 16 | 2019-12-09 | 2026-02-10 |
| Biomarker for Homozygous Familial Hypercholesterolemia (BioHoFH) Lipoprotein Lipase Deficiency, Inborn Error of Lipid Metabolism | Withdrawn | CENTOGENE GmbH Rostock | 2018-08-20 | 2023-02-13 | ||
| Phase 2 Study of AKCEA-ANGPTL3-LRx (ISIS 703802) in Participants With Familial Chylomicronemia Syndrome (FCS) AKCEA-ANGPTL3-LRx - Familial Chylomicronemia Syndrome, Lipoprotein Lipase Deficiency | Phase 2 | Completed | Akcea Therapeutics | 3 | 2017-12-21 | 2021-01-07 |
| Lipoprotein Lipase Enzyme Activity Assay Validation and Clinical Assessment Heparin - Lipoprotein Lipase Deficiency | Completed | University of Colorado, Denver | 12 | 2016-03-01 | 2019-07-11 | |
| The Approach Open Label Study: A Study of Volanesorsen (Formerly IONIS-APOCIIIRx) in Participants With Familial Chylomicronemia Syndrome Volanesorsen - Familial Chylomicronemia Syndrome, Lipoprotein Lipase Deficiency | Phase 3 | Completed | Akcea Therapeutics | 68 | 2015-12-23 | 2021-08-26 |
| Glybera Registry, Lipoprotein Lipase Deficient (LPLD) Patients Observational study - Lipoprotein Lipase Deficiency, Familial Hyperlipoproteinemia Type 1 | Completed | UniQure Biopharma B.V. | 16 | 2014-06-27 | 2023-11-27 | |
| Study to Re-assess and Re-confirm Data Previously Recorded About the Incidence and Severity of Acute Abdominal "Pancreatitis" Episodes in Lipoprotein Lipase Deficient (LPLD) Subjects Previously Enrolled on AMT Clinical Studies Lipoprotein Lipase Deficiency | Unknown | Amsterdam Molecular Therapeutics | 22 | 2010-11-01 | 2011-10-07 |
Hyperlipoproteinemia Type I (7) · Familial hyperchylomicronemia syndrome (2) · Lipid Metabolism, Inborn Errors (2) · Arcus Senilis (1) · Dyslipidemias (1) · Genetic Diseases, Inborn (1) · Hyperlipidemias (1) · Hyperlipoproteinemia Type II (1) · Hyperlipoproteinemias (1) · Lipid Metabolism Disorders (1) · Metabolic Diseases (1) · Metabolism, Inborn Errors (1)
Congenital, Hereditary, and Neonatal Diseases and Abnormalities (7) · Nutritional and Metabolic Diseases (7) · Dyslipidemias (6) · Genetic Diseases, Inborn (6) · Hyperlipidemias (6) · Hyperlipoproteinemias (6) · Lipid Metabolism Disorders (6) · Metabolic Diseases (6) · Metabolism, Inborn Errors (6) · Lipid Metabolism, Inborn Errors (5) · Corneal Diseases (1) · Corneal Opacity (1) · Eye Diseases (1)
Heparin (2) · IONIS-ANGPTL3-LRx (1) · ISIS 304801 (1) · Observation (1) · vupanorsen (1)
Akcea Therapeutics (2) · Amsterdam Molecular Therapeutics (1) · CENTOGENE GmbH Rostock (1) · UniQure Biopharma B.V. (1) · University of Colorado, Denver (1) · Université de Sherbrooke (1)
Canada (4) · Germany (3) · Brazil (1) · France (1) · India (1) · Israel (1) · Italy (1) · Netherlands (1) · South Africa (1) · Spain (1) · Sri Lanka (1) · United Kingdom (1) · United States (1)
Daniel Gaudet, MD, PhD (1) · Maurizio Averna, Prof (1) · Peter Bauer, Prof. (1) · Robert Eckel, MD (1)
2015 (1), UL1TR001082 (1)