2 completed, 1 recruiting. 3 Phase 2, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 3 | Completed 2, Recruiting 1 |
| Phase 1 | 2 | Completed 1, Recruiting 1 |
Follow Hyperargininemia: new trials by email Literature Review of Hyperargininemia trials Research Report on Hyperargininemia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Phase 1/2 Study of KRRO-121 in Healthy Volunteers and Patients With UCD KRRO-121, Placebo - Urea Cycle Disorders, Inborn, Urea Cycle Disorders | Phase 1 / Phase 2 | Recruiting | Korro Bio, Inc. | 30 | 2026-09-28 | 2026-10-08 |
| A Study of AEB1102 (Pegzilarginase) in Patients With Arginase 1 Deficiency AEB1102 - Arginase I Deficiency, Hyperargininemia | Phase 2 | Completed | Immedica Pharma AB | 14 | 2017-12-07 | 2026-09-24 |
| A Phase 1/2 Study of AEB1102 in Patients With Arginase I Deficiency AEB1102 - Arginase I Deficiency, Hyperargininemia | Phase 1 / Phase 2 | Completed | Aeglea Biotherapeutics | 16 | 2016-06-01 | 2019-06-12 |
Adult-onset citrullinemia type 2 (1) · Argininosuccinic Aciduria (1) · N-acetyl glutamate synthetase deficiency (1) · Ornithine Carbamoyltransferase Deficiency Disease (1) · Urea Cycle Disorders, Inborn (1)
Amino Acid Metabolism, Inborn Errors (3) · Brain Diseases (3) · Brain Diseases, Metabolic (3) · Brain Diseases, Metabolic, Inborn (3) · Central Nervous System Diseases (3) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (3) · Genetic Diseases, Inborn (3) · Metabolic Diseases (3) · Metabolism, Inborn Errors (3) · Nervous System Diseases (3) · Nutritional and Metabolic Diseases (3) · Urea Cycle Disorders, Inborn (2) · Genetic Diseases, X-Linked (1)
Aeglea Biotherapeutics (1) · Immedica Pharma AB (1) · Korro Bio, Inc. (1)
Canada (2) · Portugal (2) · United Kingdom (2) · United States (2) · Australia (1)
Josie Gayton (1) · Mattias Rudebeck, PhD MSc BMedSc (1)