2 completed, 2 recruiting, 2 terminated, 1 active not recruiting. 5 Not applicable, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 5 | Active not recruiting 1, Completed 1, Enrolling by invitation 1, Recruiting 1, Unknown 1 |
| Phase 1 | 1 | Terminated 1 |
Follow Hydrops Fetalis: new trials by email Literature Review of Hydrops Fetalis trials Research Report on Hydrops Fetalis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Uncovering the Etiologies of Non-immune Hydrops Fetalis Whole genome sequencing - Non-Immune Hydrops Fetalis | Not applicable | Enrolling by invitation | University of California, San Francisco | 500 | 2022-03-01 | 2026-04-17 |
| In-utero Hematopoietic Stem Cell Transplantation for the Treatment of Fetuses With Bart's Hydrops Fetalis Syndrome in-utero HSCT - Haemoglobin Barts Hydrops | Not applicable | Recruiting | Chinese University of Hong Kong | 10 | 2021-10-01 | 2023-04-12 |
| Multicentric Prospective Study to Screen Inborn Errors of Metabolism in Non-immune Hydrops (NIH) Fetalis by Massively Parallel Sequencing NON-IMMUNE HYDROPS FETALIS diagnosis - Non-Immune Hydrops Fetalis | Not applicable | Completed | Hospices Civils de Lyon | 71 | 2021-04-12 | 2024-11-08 |
| Hydrops: Diagnosing & Redefining Outcomes With Precision Study Exome sequencing - Hydrops Fetalis, Birth Defect | Not applicable | Active not recruiting | University of California, San Francisco | 500 | 2018-10-11 | 2026-04-17 |
| Fetal Electrophysiologic Abnormalities in High-Risk Pregnancies Associated With Fetal Demise Fetal Magnetocardiogram and Neonatal Electrocardiogram, Substudy only: Maternal/Infant Pharmacogenomic assessment postnatally - High Risk Pregnancy, Congenital Heart Disease | Recruiting | Medical College of Wisconsin | 30 | 2018-07-01 | 2026-03-04 | |
| In Utero Hematopoietic Stem Cell Transplantation for Alpha-thalassemia Major (ATM) in utero hematopoietic stem cell transplantation - Alpha Thalassemia Major, Hemoglobinopathy; With Thalassemia | Phase 1 | Terminated | University of California, San Francisco | 6 | 2017-10-05 | 2025-01-27 |
| Prospective Observational Cohort Study of Fetal Atrial Flutter & Supraventricular Tachycardia Prospective observational cohorts - Atrial Flutter, Tachycardia, Supraventricular | Completed | Edgar Jaeggi | 330 | 2017-06-08 | 2025-05-31 | |
| Precision Medical Research of Non-immune Fetal Hydrops (NIFH)-From Prenatal Diagnosis to Intrauterine Treatment intrauterine intervention - Fetal Hydrops | Not applicable | Unknown | Shanghai First Maternity and Infant Hospital | 144 | 2016-12-01 | 2016-12-12 |
| Amniotic Fluid Tandem Mass Spectrometry for Pregnancies Complicated by NIH and Severe Symmetrical IUGR Tandem MS test for inborn errors of metabolism - Hydrops Fetalis, Fetal Growth Retardation | Terminated | Obstetrix Medical Group | 48 | 2006-03-01 | 2014-12-19 |
Congenital Abnormalities (2) · Atrial Flutter (1) · Brugada Syndrome (1) · Fetal Death (1) · Fetal Growth Retardation (1) · Fetofetal Transfusion (1) · Gastroschisis (1) · Heart Defects, Congenital (1) · Hemoglobinopathies (1) · Long QT Syndrome (1) · Stillbirth (1) · Sudden Infant Death (1) · Tachycardia, Atrioventricular Nodal Reentry (1) · Tachycardia, Ectopic Atrial (1)
Congenital, Hereditary, and Neonatal Diseases and Abnormalities (9) · Edema (9) · Erythroblastosis, Fetal (9) · Female Urogenital Diseases and Pregnancy Complications (9) · Fetal Diseases (9) · Genetic Diseases, Inborn (9) · Hematologic Diseases (9) · Hemic and Lymphatic Diseases (9) · Immune System Diseases (9) · Pathological Conditions, Signs and Symptoms (9) · Pregnancy Complications (9) · Signs and Symptoms (9) · Urogenital Diseases (9) · Hemoglobinopathies (8) · Thalassemia (8)
Exome (1)
University of California, San Francisco (3) · Chinese University of Hong Kong (1) · Edgar Jaeggi (1) · Hospices Civils de Lyon (1) · Medical College of Wisconsin (1) · Obstetrix Medical Group (1) · Shanghai First Maternity and Infant Hospital (1)
United States (6) · France (2) · Hong Kong (2) · Australia (1) · Brazil (1) · Canada (1) · Czechia (1) · Finland (1) · Netherlands (1) · Russia (1) · Spain (1) · Sweden (1) · Switzerland (1) · United Kingdom (1)
Edgar Jaeggi, MD, FRCPC (1) · Janette F Strasburger, MD (1) · Karrie Francois, MD (1) · Mary Norton, MD (1) · Teresa Sparks, MD (1) · Teresa Sparks, MD, MAS (1) · Tippi Mackenzie, MD (1)
PMID 27862048, PMID 33027564, PMID 39891377, PMID 41984996
K12HD001262 (1), R01HD107190 (1), R01HL143485 (1)