5 completed, 1 recruiting, 1 withdrawn. 7 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 7 | Completed 5, Recruiting 1, Withdrawn 1 |
Follow Hereditary Angioedema: new trials by email Literature Review of Hereditary Angioedema trials Research Report on Hereditary Angioedema
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Safety and Effectiveness of Sebetralstat (KVD900) for Short-Term Prophylaxis Before Procedures in People With Hereditary Angioedema (KONTROL) KVD900 600 mg - Hereditary Angioedema | Phase 4 | Recruiting | KalVista Pharmaceuticals, Ltd. | 100 | 2026-08-17 | 2026-09-17 |
| Safety Study in Subjects ≥ 12 Years of Age With Hereditary Angioedema Switching to Garadacimab Garadacimab - Hereditary Angioedema | Phase 4 | Completed | CSL Behring | 18 | 2025-04-28 | 2026-07-23 |
| Treatment of Hereditary Angioedema Prodrome with Recombinant C1-esterase Inhibitor (Ruconest) Ruconest - Hereditary Angioedema | Phase 4 | Completed | Bernstein Clinical Research Center | 5 | 2018-08-14 | 2024-11-15 |
| A Call Center During HAE Attacks (SOS HAE) phone to the call center - Hereditary Angioedema | Phase 4 | Completed | Assistance Publique - Hôpitaux de Paris | 200 | 2013-03-01 | 2016-12-13 |
| Efficacy, Safety and Tolerability of Icatibant for the Treatment of HAE Icatibant - Hereditary Angioedema | Phase 4 | Completed | Massachusetts General Hospital | 19 | 2011-12-01 | 2016-10-18 |
| C1-INH Compared to Placebo at the Time of Prodromal Symptoms for Hereditary Angioedema (HAE) Exacerbation C-1-esterase, placebo - Hereditary Angioedema | Phase 4 | Withdrawn | Penn State University | 2010-07-01 | 2012-11-30 | |
| A Study to Evaluate the Safety and Effect of Escalating Doses of CINRYZE C1 inhibitor (human) [C1 INH] - Hereditary Angioedema | Phase 4 | Completed | Shire | 20 | 2009-08-31 | 2021-06-23 |
Angioedemas, Hereditary (7) · Angioedema (1) · Genetic Diseases, Inborn (1) · Rare Diseases (1)
Cardiovascular Diseases (7) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (7) · Hereditary Complement Deficiency Diseases (7) · Hypersensitivity (7) · Hypersensitivity, Immediate (7) · Immune System Diseases (7) · Immunologic Deficiency Syndromes (7) · Primary Immunodeficiency Diseases (7) · Skin Diseases (7) · Skin Diseases, Vascular (7) · Skin and Connective Tissue Diseases (7) · Urticaria (7) · Vascular Diseases (7) · Angioedema (6) · Genetic Diseases, Inborn (6)
Complement C1 (1) · Complement C1 Inhibitor Protein (1) · Methods (1) · SERPING1 protein, human (1) · conestat alfa (1) · icatibant (1) · sebetralstat (1)
Assistance Publique - Hôpitaux de Paris (1) · Bernstein Clinical Research Center (1) · CSL Behring (1) · KalVista Pharmaceuticals, Ltd. (1) · Massachusetts General Hospital (1) · Penn State University (1) · Shire (1)
United States (5) · Canada (1) · France (1) · Germany (1)
Aleena Banerji, M.D. (1) · Jonathan Bernstein, MD (1) · Michael Lunn, DO (1)