2 completed, 2 recruiting, 1 not yet recruiting. 5 Phase 2, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 5 | Completed 2, Recruiting 2, Not yet recruiting 1 |
| Phase 3 | 2 | Completed 1, Recruiting 1 |
Follow Graves Orbitopathy: new trials by email Literature Review of Graves Orbitopathy trials Research Report on Graves Orbitopathy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Prophylactic Treatment of Graves Ophthalmopathy (GO) in Newly Diagnosed Graves' Disease (GD) With Atorvastatin (ATORGO) Atorvastatin - Graves Disease, Graves Disease (Basedow's Disease) | Phase 2 | Not yet recruiting | Region Skane | 554 | 2026-11-01 | 2026-10-20 |
| Tofacitinib for Glucocorticoid-Resistant Moderate-to-Severe Thyroid Eye Disease Tofacitinib - Thyroid Eye Disease, TED, Graves Ophthalmopathy | Phase 2 | Recruiting | The First Affiliated Hospital of Xiamen University | 8 | 2026-04-24 | 2026-04-29 |
| A Study to Evaluate the Efficacy and Safety of LASN01 in Patients With Thyroid Eye Disease LASN01, Placebo - Thyroid Eye Disease, Graves Ophthalmopathy | Phase 2 | Completed | Lassen Therapeutics Inc. | 41 | 2024-03-05 | 2026-03-09 |
| Extension Study of Two Doses of Linsitinib in Subjects With Active, Moderate to Severe Thyroid Eye Disease (TED) linsitinib - Thyroid Eye Disease, Graves Orbitopathy | Phase 2 / Phase 3 | Recruiting | Sling Therapeutics, Inc. | 75 | 2023-10-11 | 2025-02-25 |
| A Phase 2b, Study of Linsitinib in Subjects With Active, Moderate to Severe Thyroid Eye Disease (TED) Linsitinib, Placebo - Thyroid Eye Disease, Graves Orbitopathy | Phase 2 / Phase 3 | Completed | Sling Therapeutics, Inc. | 90 | 2022-07-01 | 2026-09-23 |
Graves Ophthalmopathy (5) · Endocrine System Diseases (3) · Exophthalmos (3) · Eye Diseases (3) · Orbital Diseases (3) · Hashimoto Disease (2) · Thyroid Diseases (2) · Graves Disease (1)
Autoimmune Diseases (5) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (5) · Eye Diseases, Hereditary (5) · Genetic Diseases, Inborn (5) · Goiter (5) · Hyperthyroidism (5) · Immune System Diseases (5) · Graves Disease (4) · Thyroid Diseases (3) · Endocrine System Diseases (2) · Exophthalmos (2) · Eye Diseases (2) · Orbital Diseases (2) · Thyroiditis (2) · Thyroiditis, Autoimmune (2)
3-(8-amino-1-(2-phenylquinolin-7-yl)imidazo(1,5-a)pyrazin-3-yl)-1-methylcyclobutanol (2) · Atorvastatin (1) · tofacitinib (1)
Sling Therapeutics, Inc. (2) · Lassen Therapeutics Inc. (1) · Region Skane (1) · The First Affiliated Hospital of Xiamen University (1)
United States (3) · Spain (2) · United Kingdom (2) · Canada (1) · China (1) · Italy (1) · Sweden (1)
Fangsen Xiao, MD (1) · Tereza Planck (1)
2023 (1)