5 recruiting, 4 not yet recruiting, 2 enrolling by invitation, 1 withdrawn. 12 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Early Phase 1 | 12 | Recruiting 5, Not yet recruiting 4, Enrolling by invitation 2, Withdrawn 1 |
Follow Glomerulonephritis, IGA: new trials by email Literature Review of Glomerulonephritis, IGA trials Research Report on Glomerulonephritis, IGA
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Clinical Study Evaluating the Safety and Efficacy of GT719 Universal Cell Injection in the Treatment of Immune-mediated Kidney Diseases CD19-targeted iNKT Cell Injection - IgA Nephropathy (IgAN), Membranous Nephropathy | Early Phase 1 | Not yet recruiting | Grit Biotechnology | 30 | 2027-08-01 | 2026-09-11 |
| RD06-05 Universal CD19/BCMA CAR-T for Refractory Pediatric Autoimmune Diseases RD06-05 CART Cell Infusion - Autoimmune Diseases, SLE - Systemic Lupus Erythematosus | Early Phase 1 | Not yet recruiting | The Children's Hospital of Zhejiang University School of Medicine | 30 | 2026-07-01 | 2026-06-29 |
| CD19/BCMA UCAR-T for B Cell-Related Autoimmune Disease QT-219CX - Autoimmune Diseases, Systemic Lupus Erthematosus (SLE) | Early Phase 1 | Recruiting | The Children's Hospital of Zhejiang University School of Medicine | 15 | 2026-05-08 | 2026-05-14 |
| A Study of YKST02 in Participants With Primary IgA Nephropathy YKST02 - Primary IgA Nephropathy | Early Phase 1 | Recruiting | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 12 | 2026-05-06 | 2026-05-12 |
| Efficacy and Safety of CD19 CAR-γδ T Cells in the Treatment of Relapsed/Refractory Autoimmune Nephropathy CD19 CAR-γδ T cell - Membranous Nephropathy, Lupus Nephritis (LN) | Early Phase 1 | Not yet recruiting | Air Force Military Medical University, China | 15 | 2026-05-01 | 2026-04-16 |
| Allogeneic CD19/BCMA CAR-T for B Cell-Related Autoimmune Disease UCAR T-cell - Autoimmune Diseases, Systemic Lupus Erthematosus (SLE) | Early Phase 1 | Recruiting | The Children's Hospital of Zhejiang University School of Medicine | 15 | 2026-04-01 | 2026-04-02 |
| An Exploratory Clinical Study of Anti-CD19/BCMA Chimeric Antigen Receptor NK Cell Injection in the Treatment of IgA Nephropathy anti-CD19/BCMA CAR NK cells - IgA Nephropathy (IgAN) | Early Phase 1 | Withdrawn | Jieyang People's Hospital | 2025-07-30 | 2025-07-04 | |
| A Study of Anti-CD19/BCMA Universal CAR-T Cell Therapy RD06-05 in Patients With Autoimmune Diseases. RD06-05 CART Cell Injection - SLE, LN | Early Phase 1 | Recruiting | Nanjing Bioheng Biotech Co., Ltd. | 96 | 2025-07-24 | 2026-08-03 |
| A Study of Cizutamig in Patients With Immunoglobulin A Nephropathy Biological: cizutamig - Immunoglobulin A Nephropathy (IgAN) | Early Phase 1 | Enrolling by invitation | Peking University First Hospital | 15 | 2025-07-16 | 2025-08-22 |
| The MIMIGA Study is a Randomized, Double-blind, Placebo-controlled Crossover Trial Evaluating the Safety and Efficacy of SCFA vs. Placebo. Administered Orally Once Daily With Standard Care, it Aims to Prevent CKD Progression in Biopsy-proven IgA Nephropathy by Modulating the Gut Microbiome. SCFA → Placebo (Sequence SP) and Placebo → SCFA (Sequence PS) - Primary IgA Nephropathy | Early Phase 1 | Enrolling by invitation | University Hospital, Martin | 120 | 2025-03-01 | 2026-08-06 |
| Anti-CD19/BCMA CAR-NK Cells in Patients With B Cell Mediated Autoimmune Disease anti-CD19/BCMA CAR NK cells (KN5601) - Autoimmune Diseases, Systemic Lupus Erthematosus | Early Phase 1 | Recruiting | The Children's Hospital of Zhejiang University School of Medicine | 36 | 2025-01-30 | 2025-12-01 |
| IM19 CAR-T Cell Therapy for IgA Nephropathy Patients and Membranous Nephropathy Patients IM19 chimeric antigen receptor T cell injection - IgA Nephropathy, Membranous Nephropathy | Early Phase 1 | Not yet recruiting | Beijing Immunochina Medical Science & Technology Co., Ltd. | 12 | 2024-12-13 | 2024-11-26 |
Autoimmune Diseases (4) · Nephrotic Syndrome (4) · Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis (3) · Glomerulonephritis, Membranous (3) · Scleroderma, Systemic (2) · Anti-Glomerular Basement Membrane Disease (1) · Lupus Erythematosus, Systemic (1) · Lupus Nephritis (1) · Renal Insufficiency, Chronic (1)
Female Urogenital Diseases (12) · Female Urogenital Diseases and Pregnancy Complications (12) · Glomerulonephritis (12) · Immune System Diseases (12) · Kidney Diseases (12) · Male Urogenital Diseases (12) · Nephritis (12) · Urogenital Diseases (12) · Urologic Diseases (12) · Autoimmune Diseases (8) · Skin and Connective Tissue Diseases (6) · Connective Tissue Diseases (4) · Nephrosis (4) · Skin Diseases (4) · Cardiovascular Diseases (3)
The Children's Hospital of Zhejiang University School of Medicine (4) · Air Force Military Medical University, China (1) · Beijing Immunochina Medical Science & Technology Co., Ltd. (1) · Grit Biotechnology (1) · Jieyang People's Hospital (1) · Nanjing Bioheng Biotech Co., Ltd. (1) · Peking University First Hospital (1) · Union Hospital, Tongji Medical College, Huazhong University of Science and Technology (1) · University Hospital, Martin (1)
China (10) · Slovakia (1)
Jianhua Mao (1)