2 completed, 2 recruiting. 4 Phase 2, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 4 | Completed 2, Recruiting 2 |
| Phase 1 | 1 | Completed 1 |
Follow Fuchs Endothelial Corneal Dystrophy: new trials by email Literature Review of Fuchs Endothelial Corneal Dystrophy trials Research Report on Fuchs Endothelial Corneal Dystrophy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| DT-168 in Keratoplasty Patients With Fuchs Endothelial Corneal Dystrophy DT-168 - Fuchs Endothelial Corneal Dystrophy, Fuchs | Phase 2 | Recruiting | Design Therapeutics, Inc. | 70 | 2025-07-30 | 2026-09-28 |
| A Multicenter Study Assessing the Efficacy and Safety of STN1010904 Ophthalmic Suspension 0.03% and 0.1% Compared With Vehicle in Subjects With Fuchs Endothelial Corneal Dystrophy (FECD) STN1010904 ophthalmic suspension 0.03% BID, STN1010904 ophthalmic suspension 0.1% BID, Placebo (Vehicle) BID - Fuchs Endothelial Corneal Dystrophy | Phase 2 | Completed | Santen Inc. | 86 | 2022-05-19 | 2026-08-07 |
| Targeting Reactive Oxygen Species Production as a Novel Therapeutic in Fuch's Endothelial Corneal Dystrophy N-acetyl cysteine (NAC) 10% solution, N-acetyl cysteine (NAC) 20% solution, Visine Dry Eye Relief eye drops - Fuchs Endothelial Corneal Dystrophy | Phase 2 | Recruiting | Massachusetts Eye and Ear Infirmary | 45 | 2020-09-16 | 2026-09-02 |
| A Phase 1/ Phase 2 Study of TTHX1114(NM141) TTHX1114(NM141), Vehicle (placebo) - Corneal Endothelial Dystrophy, Fuchs Endothelial Corneal Dystrophy | Phase 1 / Phase 2 | Completed | Trefoil Therapeutics, Inc. | 22 | 2020-08-19 | 2023-10-30 |
Fuchs' Endothelial Dystrophy (4) · Corneal Dystrophy, Posterior Polymorphous, 1 (1)
Congenital, Hereditary, and Neonatal Diseases and Abnormalities (4) · Corneal Diseases (4) · Corneal Dystrophies, Hereditary (4) · Eye Diseases (4) · Eye Diseases, Hereditary (4) · Genetic Diseases, Inborn (4)
Acetylcysteine (1) · BID protein, human (1) · Solutions (1)
Design Therapeutics, Inc. (1) · Massachusetts Eye and Ear Infirmary (1) · Santen Inc. (1) · Trefoil Therapeutics, Inc. (1)
United States (4) · France (1) · India (1)
Thomas M Tremblay, RN BSN (1) · Ula Jurkunas, MD (1)