3 completed. 3 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 3 | Completed 3 |
Follow Drug-induced QT Prolongation: new trials by email Literature Review of Drug-induced QT Prolongation trials Research Report on Drug-induced QT Prolongation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Electrophysiological Effects of Potential QT Prolonging Drugs Clarithromycin, Pimozide, Placebo (Part 1) - Drug-induced QT Prolongation, Pharmacokinetics | Phase 1 | Completed | Food and Drug Administration (FDA) | 44 | 2023-03-21 | 2023-06-22 |
| CiPA Phase 1 ECG Biomarker Validation Study Ranolazine, Verapamil, Lopinavir / Ritonavir - Drug-induced QT Prolongation, Pharmacokinetics | Phase 1 | Completed | Food and Drug Administration (FDA) | 60 | 2017-03-14 | 2020-01-18 |
| Ability of Late Sodium or Calcium Current Block to Balance the ECG Effects of Potassium Current Block Dofetilide, Mexiletine, Lidocaine - Drug-induced QT Prolongation, Pharmacokinetics | Phase 1 | Completed | Food and Drug Administration (FDA) | 22 | 2014-05-01 | 2016-06-08 |
Diltiazem (2) · Moxifloxacin (2) · dofetilide (2) · Chloroquine (1) · Clarithromycin (1) · Cobicistat (1) · Lidocaine (1) · Lopinavir (1) · Mexiletine (1) · Pimozide (1) · Ranolazine (1) · Sodium Chloride (1) · Verapamil (1)
Food and Drug Administration (FDA) (3)
United States (2)
Carlos Sanabria, MD (2) · Jennifer Boston, MSN, APNP (1)