3 completed, 1 terminated, 1 withdrawn. 3 Phase 3, 2 Phase 2.
By phase and status
Follow Dialysis-dependent Chronic Kidney Disease: new trials by email Literature Review of Dialysis-dependent Chronic Kidney Disease trials Research Report on Dialysis-dependent Chronic Kidney Disease
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix .
Trial Phase Status Sponsor Enrollment Start Updated
Study of Vadadustat in Hemodialysis Participants With Anemia Switching From Epoetin Alfa Vadadustat, Epoetin Alfa, Vadadustat TIW - Anemia, Dialysis-dependent Chronic Kidney Disease Phase 2 Completed 175 2019-01-31 2022-09-29 Study to Evaluate Three Times Per Week (TIW) Oral Dosing of Vadadustat for Anemia in Subjects With Dialysis-Dependent Chronic Kidney Disease (DD-CKD) Vadadustat, Darbepoetin alfa - Anemia, Dialysis-Dependent Chronic Kidney Disease Phase 3 Withdrawn 2017-08-01 2018-11-05 Study to Evaluate Vadadustat for Anemia in Subjects With Dialysis-Dependent Chronic Kidney Disease (DD-CKD) Who Are Hyporesponsive to Erythropoiesis Stimulating Agents vadadustat, epoetin alfa - Anemia, Dialysis-Dependent Chronic Kidney Disease Phase 2 Terminated 2 2017-05-02 2021-02-21 Efficacy and Safety Study to Evaluate Vadadustat for the Maintenance Treatment of Anemia in Participants With Dialysis-dependent Chronic Kidney Disease (DD-CKD) Vadadustat, Darbepoetin alfa - Anemia, Dialysis-Dependent Chronic Kidney Disease Phase 3 Completed 3554 2016-08-01 2022-06-28 Efficacy and Safety Study to Evaluate Vadadustat for the Correction or Maintenance Treatment of Anemia in Participants With Incident Dialysis-dependent Chronic Kidney Disease (DD-CKD) Vadadustat, Darbepoetin alfa - Anemia, Dialysis-Dependent Chronic Kidney Disease Phase 3 Completed 369 2016-07-01 2022-07-18
Narrower conditions Anemia (5) · Renal Insufficiency, Chronic (3) · Renal Insufficiency (2)
Broader conditions Hematologic Diseases (5) · Hemic and Lymphatic Diseases (5) · Chronic Disease (3) · Disease Attributes (3) · Female Urogenital Diseases (3) · Female Urogenital Diseases and Pregnancy Complications (3) · Kidney Diseases (3) · Male Urogenital Diseases (3) · Pathologic Processes (3) · Pathological Conditions, Signs and Symptoms (3) · Urogenital Diseases (3) · Urologic Diseases (3) · Renal Insufficiency (1)
Interventions vadadustat (5) · Darbepoetin alfa (3) · Epoetin Alfa (2)
Sponsors Akebia Therapeutics (5)
Countries United States (5) · Argentina (2) · Brazil (2) · Germany (2) · Italy (2) · Mexico (2) · Poland (2) · Portugal (2) · Russia (2) · South Korea (2) · Ukraine (2) · Australia (1) · Bulgaria (1) · Canada (1) · France (1)
Results publications PMID 36005278 , PMID 33913638 , PMID 37096396 , PMID 40359056
NIH funding 2016 (2)