3 completed, 2 recruiting, 1 unknown. 6 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 6 | Completed 3, Recruiting 2, Unknown 1 |
| Phase 2 | 1 | Completed 1 |
Follow Corneal Edema: new trials by email Literature Review of Corneal Edema trials Research Report on Corneal Edema
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| PVEK Corneal Implant For Treatment of Corneal Edema Precise Vision Endothelial Keratoplasty (PVEK) Implant - Corneal Edema, Fuchs' Endothelial Dystrophy | Phase 1 | Recruiting | Precise Bio | 15 | 2025-09-16 | 2026-01-12 |
| A Phase 1/2 Study of AURN001 in Subjects With Corneal Edema Secondary to Corneal Endothelial Dysfunction (ABA-1) AURN001, Corneal Endothelial Cells, Y27632 - Corneal Edema, Corneal Endothelial Dysfunction | Phase 1 / Phase 2 | Completed | Aurion Biotech | 97 | 2023-10-18 | 2025-12-17 |
| Study to Assess Safety and Tolerability of Multiple Doses of EO2002 EO2002, Ripasudil - Corneal Edema, Corneal Endothelial Dystrophy | Phase 1 | Recruiting | Asociación para Evitar la Ceguera en México | 12 | 2022-11-08 | 2025-12-08 |
| A Safety and Efficacy Study of Corneal Injection for Endothelial Dysfunction Using Human Corneal Endothelial Cell Therapy in Subjects With Corneal Edema Secondary to Endothelial Dysfunction HCEC-1 - Corneal Edema | Phase 1 | Completed | Aurion Biotech | 22 | 2022-03-24 | 2024-08-19 |
| Study of Safety and Tolerability of EO2002 in the Treatment of Corneal Edema EO2002, EO2002 low dose, EO2002 mid dose - Corneal Edema, Corneal Endothelial Dysfunction | Phase 1 | Completed | Emmecell | 42 | 2021-06-22 | 2025-03-05 |
| Phase 1 Study to Evaluate the Safety and Tolerability of EO1404 in the Treatment of Corneal Edema EO1404, Endothelial brushing or Descemet stripping - Corneal Edema, Fuchs Dystrophy | Phase 1 | Unknown | Valeria Sanchez-Huerta | 35 | 2016-05-04 | 2019-12-10 |
Fuchs' Endothelial Dystrophy (4) · Corneal Dystrophy, Posterior Polymorphous, 1 (3)
Corneal Diseases (6) · Eye Diseases (6) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (4) · Corneal Dystrophies, Hereditary (4) · Eye Diseases, Hereditary (4) · Genetic Diseases, Inborn (4)
Drug Implants (1) · K-115 (1) · Y 27632 (1)
Aurion Biotech (2) · Asociación para Evitar la Ceguera en México (1) · Emmecell (1) · Precise Bio (1) · Valeria Sanchez-Huerta (1)
Mexico (2) · United States (2) · Armenia (1) · Canada (1) · El Salvador (1) · Israel (1)
Michael Minouni, Prof. (1) · Noelia Kunzevitzky (1) · Valeria Sanchez Huerta, MD (1) · Valeria Sanchez-Huerta, MD (1)