25 completed, 10 unknown, 2 not yet recruiting, 2 recruiting. 36 Not applicable, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 36 | Completed 21, Unknown 10, Not yet recruiting 2, Recruiting 2, Terminated 1 |
| Phase 2 | 2 | Completed 2 |
Follow CLASS II DIVISION 1 MALOCCLUSION: new trials by email Literature Review of CLASS II DIVISION 1 MALOCCLUSION trials Research Report on CLASS II DIVISION 1 MALOCCLUSION
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Twin-Block and LIPUS for TMJ Outcomes in Skeletal Class II Patients ultrasound - CLASS II DIVISION 1 MALOCCLUSION | Not applicable | Recruiting | Al-Azhar University | 24 | 2026-06-18 | 2026-06-30 |
| The Effectiveness of the Twin Block and Carriere Motion Appliances in Post-pubertal Patients and an Evaluation of the Impact of Class II Malocclusion and Its Correction on Oral Health-related Quality of Life CTB, CMA - CLASS II DIVISION 1 MALOCCLUSION, Class II Malocclusion | Not applicable | Not yet recruiting | Aslam Alkadhimi | 88 | 2026-03-01 | 2025-12-18 |
| EVALUATION OF TREATMENT CHANGES IN CLASS II DIVISION 1 MALOCCLUSION DURING EN MASSE RETRACTION OF UPPER ANTERIOR TEETH USING MINI IMPLANTS PLACED AT INFRAZYGOMATIC CREST AND INTERRADICULAR SITES A RANDOMIZED CLINICAL TRIAL. retraction of anterior teeth using mini implants placed at infrazygomatic crest., retraction of anterior teeth using mini implants placed at interradicular sites. - CLASS II DIVISION 1 MALOCCLUSION | Not applicable | Recruiting | Postgraduate Institute of Dental Sciences Rohtak | 30 | 2025-10-01 | 2026-02-12 |
| Root Shortening With Three Methods of Upper Front Teeth Retraction Bidimensional Bracket System, Hybrid Dual-Section Archwire, Conventional Sliding Mechanics - CLASS II DIVISION 1 MALOCCLUSION | Not applicable | Completed | Damascus University | 60 | 2025-07-02 | 2026-08-04 |
| A Novel Bi-dimensional Archwire for Miniscrew-supported En-masse Retraction Bi-dimensional archwire - Malocclusion Class II, CLASS II DIVISION 1 MALOCCLUSION | Not applicable | Completed | Damascus University | 6 | 2025-07-01 | 2026-06-24 |
| Mandibular Advancement Planning Based on Clinical Overjet mandibular advancement with acrylic splint Herbst Appliance - Overjet, Class II Division 1 Malocclusion | Not applicable | Not yet recruiting | IRCCS Ospedale San Raffaele | 50 | 2024-10-30 | 2024-10-23 |
| External Root Resorption and Periodontal Status During Retraction of the Upper Anterior Teeth Electric stimulation removabel device, Traditional retraction method. - Class II Division 1 Malocclusion | Not applicable | Completed | Damascus University | 34 | 2023-11-01 | 2025-03-12 |
| Evaluating the Efficacy of the Sliding Mechanisms on Round-section Arch Wire Round-cross-section archwire, Rectangular-cross-section archwire - CLASS II DIVISION 1 MALOCCLUSION | Not applicable | Completed | Damascus University | 38 | 2023-07-07 | 2025-11-24 |
| Patient-related Outcomes When Accelerating Upper Canine Retraction With Fixed Orthodontic Appliances Electric stimulation removable appliance, Traditional orthodontic fixed appliance without accleration - Class II Division 1 Malocclusion | Not applicable | Completed | Damascus University | 40 | 2023-05-01 | 2025-03-20 |
| Cephalometric Changes Following Retraction of the Upper Anterior Teeth Stimulated by Low-intensity Electrical Current Electrical stimulation, Orthodontic treatment without acceleration - Class II Division 1 Malocclusion | Not applicable | Completed | Damascus University | 36 | 2023-05-01 | 2025-01-14 |
| Pain and Comfort During Functional Orthodontic Treatment With Laser or Ultrasounic Waves Activator + LIPUS, Activator + LLLT - CLASS II DIVISION 1 MALOCCLUSION | Not applicable | Completed | Damascus University | 40 | 2023-04-02 | 2026-10-05 |
| Activator vs the EF Class II Standard in the Treatment of Severe Overjet in Angle Class II Division 1 Malocclusion Skeletal, dental, soft tissue index changes in Activator group - Class II Division 1 Malocclusion | Not applicable | Completed | Can Tho University of Medicine and Pharmacy | 60 | 2023-04-01 | 2024-08-22 |
| The Efficacy of Tow Mechanics for Total-maxillary-arch-distalization One-jaw mechanic total maxillary arch distalization, Two-jaw mechanic total maxillary arch distalization, en-mass retraction - Malocclusion, Class II Division 1 Malocclusion | Not applicable | Completed | Hama University | 48 | 2022-05-20 | 2022-08-03 |
| Effect of Low-level Laser Therapy During Maxillary Molar Distalization Using a Skeletally Anchored Appliance Distalization - Class II Division 1 Malocclusion | Not applicable | Unknown | Al-Azhar University | 20 | 2021-12-12 | 2022-07-19 |
| Distalization Via Skeletally-anchored Distaljet Appliance With Two Approaches of Micro-osteoperforations skeletally anchored distal jet - Class II Division 1 Malocclusion | Not applicable | Unknown | Al-Azhar University | 20 | 2021-09-01 | 2022-04-25 |
| Comparative Effect of Clear Aligner Mandibular Advancement and Twin Block Appliances in Class II Malocclusion Twin block, Clear aligner with mandibular function - CLASS II DIVISION 1 MALOCCLUSION | Completed | Sichuan University | 47 | 2021-08-01 | 2024-09-24 | |
| Prefabricated Versus 3D-Printing Myofunctional Appliances 3d-Printing Myofunctional Appliance - Class II Division 1 Malocclusion | Not applicable | Unknown | Ordu University | 120 | 2021-06-01 | 2021-03-22 |
| Dentoskeletal Changes Produced by Growth Modification Appliances in Treatment of Skeletal Class II Malocclusion Removable Twin Block, Fixed Functional , AdvanSync Appliance - Class II Division 1 Malocclusion, Mandibular Retrognathism | Completed | Dr. Fareena Ghaffar | 30 | 2020-09-12 | 2022-07-29 | |
| Measuring Rate of Anteriors Retraction With Two Different Techniques palatal and buccal retraction - Class II Division 1 Malocclusion | Not applicable | Completed | Mansoura University | 30 | 2020-02-20 | 2022-09-15 |
| Bilateral Premolar Extraction vs Distalization: A Randomised Clinical Trial MAXILLARY PREMOLAR EXTRACTION, DISTALIZATION - Class II Division 1 Malocclusion | Not applicable | Unknown | Postgraduate Institute of Dental Sciences Rohtak | 34 | 2020-01-01 | 2021-02-08 |
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Malocclusion, Angle Class II (40) · Overbite (4) · Malocclusion (2) · Malocclusion, Angle Class III (1) · Pain (1)
Stomatognathic Diseases (40) · Tooth Diseases (40) · Malocclusion (38) · Neurologic Manifestations (1) · Pathological Conditions, Signs and Symptoms (1) · Signs and Symptoms (1)
Acceleration (1) · Dental Health Services (1) · Electric Stimulation (1) · Lasers, Solid-State (1) · Low-Level Light Therapy (1) · Mandibular Advancement (1) · Orthodontics (1) · Population Groups (1) · Ultrasonography (1) · proliferation regulatory factors, human urine (1)
Damascus University (16) · Postgraduate Institute of Dental Sciences Rohtak (6) · Al-Azhar University (3) · Cairo University (3) · Aristotle University Of Thessaloniki (1) · Aslam Alkadhimi (1) · Can Tho University of Medicine and Pharmacy (1) · Dr. Fareena Ghaffar (1) · Future University in Egypt (1) · Hama University (1) · IRCCS Ospedale San Raffaele (1) · Mansoura University (1) · Ordu University (1) · Queen Mary University of London (1) · Sichuan University (1)
Syria (17) · Egypt (7) · India (6) · United Kingdom (2) · China (1) · Greece (1) · Ireland (1) · Italy (1) · Pakistan (1) · Turkey (Türkiye) (1) · Vietnam (1)
Mohammad Y Hajeer, DDS,MSc,PhD (3) · Hanin Nizar Khlef, DDS,MSc (2) · Omar Heshmeh, DDS,MSc,PhD (2) · Osama H Alali, PhD (2) · Sonal Chowdhary (2) · Abdullah Jan, Postgraduate (1) · Abdulmalek M. H. Almasri (1) · Abdulmalek M. H. Almasri, DDS (1) · Ahamd S. Burhan, DDS, MSc, PhD (1) · Ahmed Afifi (1) · Ali Ammar, DDS, MSc (1) · Alison Murray, BDS, MSc, FDSRCS, MORth RCS (1) · Aslam Alkadhimi (1) · Dima M. Almrayati, DDS, MSc (1)
PMID 23814587, PMID 24326198, PMID 28389184, PMID 30712687, PMID 31677670, PMID 33563504, PMID 33876339, PMID 35094890, PMID 35295761, PMID 37796117, PMID 38471383, PMID 39307830, PMID 40462109, PMID 40762524, PMID 41045595, PMID 42240945, PMID 42673891