Childhood Diffuse Large Cell Lymphoma: Clinical Trials

9 trials for Childhood Diffuse Large Cell Lymphoma, newest first

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9 completed. 9 Phase 1, 2 Phase 2.

By phase and status

PhaseTrialsStatus
Phase 19Completed 9
Phase 22Completed 2

Follow Childhood Diffuse Large Cell Lymphoma: new trials by email Literature Review of Childhood Diffuse Large Cell Lymphoma trials Research Report on Childhood Diffuse Large Cell Lymphoma

Trials (filtered) newest first · largest first

All 9 trials

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
MORAb-004 in Treating Young Patients With Recurrent or Refractory Solid Tumors or Lymphoma
anti-endosialin/TEM1 monoclonal antibody MORAb-004, pharmacological study, laboratory biomarker analysis - Adult Nasal Type Extranodal NK/T-cell Lymphoma, Anaplastic Large Cell Lymphoma
Phase 1CompletedMorphotek272013-11-012016-01-08
MK2206 in Treating Younger Patients With Recurrent or Refractory Solid Tumors or Leukemia
Akt inhibitor MK2206, diagnostic laboratory biomarker analysis, pharmacological study - Accelerated Phase Chronic Myelogenous Leukemia, Acute Leukemias of Ambiguous Lineage
Phase 1CompletedNational Cancer Institute (NCI)452011-01-012014-04-29
Vorinostat and Bortezomib in Treating Young Patients With Refractory or Recurrent Solid Tumors, Including Central Nervous System Tumors and Lymphoma
vorinostat, bortezomib, pharmacological study - Childhood Burkitt Lymphoma, Childhood Central Nervous System Choriocarcinoma
Phase 1CompletedNational Cancer Institute (NCI)202009-08-012013-07-02
Bevacizumab and Cediranib Maleate in Treating Patients With Metastatic or Unresectable Solid Tumor, Lymphoma, Intracranial Glioblastoma, Gliosarcoma or Anaplastic Astrocytoma
bevacizumab, cediranib maleate - Adult Grade III Lymphomatoid Granulomatosis, Adult Nasal Type Extranodal NK/T-cell Lymphoma
Phase 1CompletedNational Cancer Institute (NCI)572007-05-012014-02-19
A Pilot Study to Evaluate the Co-Infusion of Ex Vivo Expanded Cord Blood Cells With an Unmanipulated Cord Blood Unit in Patients Undergoing Cord Blood Transplant for Hematologic Malignancies
cyclophosphamide, fludarabine phosphate, cyclosporine - Accelerated Phase Chronic Myelogenous Leukemia, Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome
Phase 1CompletedFred Hutchinson Cancer Center232006-04-012015-02-11
Vorinostat With or Without Isotretinoin in Treating Young Patients With Recurrent or Refractory Solid Tumors, Lymphoma, or Leukemia
vorinostat, isotretinoin - Childhood Acute Promyelocytic Leukemia (M3), Childhood Atypical Teratoid/Rhabdoid Tumor
Phase 1CompletedNational Cancer Institute (NCI)602005-08-012014-06-17
Oxaliplatin and Irinotecan in Treating Young Patients With Refractory Solid Tumors or Lymphomas
irinotecan hydrochloride, oxaliplatin - Childhood Burkitt Lymphoma, Childhood Central Nervous System Germ Cell Tumor
Phase 1CompletedNational Cancer Institute (NCI)242005-03-012013-06-05
Mycophenolate Mofetil and Cyclosporine in Reducing Graft-Versus-Host Disease in Patients With Hematologic Malignancies or Metastatic Kidney Cancer Undergoing Donor Stem Cell Transplant
fludarabine phosphate, total-body irradiation, nonmyeloablative allogeneic hematopoietic stem cell transplantation - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission
Phase 1 / Phase 2CompletedFred Hutchinson Cancer Center372003-09-012020-01-18
Fludarabine Phosphate, Low-Dose Total-Body Irradiation, and Donor Stem Cell Transplant Followed by Cyclosporine, Mycophenolate Mofetil, Donor Lymphocyte Infusion in Treating Patients With Hematopoietic Cancer
total-body irradiation, fludarabine phosphate, cyclosporine - Acute Undifferentiated Leukemia, Adult Nasal Type Extranodal NK/T-cell Lymphoma
Phase 1 / Phase 2CompletedFred Hutchinson Cancer Center212000-05-012020-01-21

Narrower conditions

Burkitt Lymphoma (9)  ·  Dendritic Cell Sarcoma, Interdigitating (9)  ·  Lymphoma, Large B-Cell, Diffuse (9)  ·  Recurrence (8)  ·  Lymphoma, Extranodal NK-T-Cell (7)  ·  Lymphoma, Large-Cell, Anaplastic (7)  ·  Precursor Cell Lymphoblastic Leukemia-Lymphoma (7)  ·  Lymphoma, B-Cell, Marginal Zone (6)  ·  Lymphoma, Follicular (6)  ·  Lymphoma, Mantle-Cell (6)  ·  Leukemia, Hairy Cell (5)  ·  Leukemia, Large Granular Lymphocytic (5)  ·  Leukemia, Lymphocytic, Chronic, B-Cell (5)  ·  Lymphoma, Large-Cell, Immunoblastic (5)  ·  Lymphoma, Non-Hodgkin (5)

Broader conditions

DNA Virus Infections (9)  ·  Disease Attributes (9)  ·  Epstein-Barr Virus Infections (9)  ·  Hemic and Lymphatic Diseases (9)  ·  Herpesviridae Infections (9)  ·  Histiocytic Disorders, Malignant (9)  ·  Histiocytosis (9)  ·  Immune System Diseases (9)  ·  Immunoproliferative Disorders (9)  ·  Infections (9)  ·  Lymphatic Diseases (9)  ·  Lymphoma (9)  ·  Lymphoma, B-Cell (9)  ·  Lymphoproliferative Disorders (9)  ·  Neoplasms (9)

Interventions

Cyclosporine (3)  ·  Mycophenolic Acid (3)  ·  fludarabine phosphate (3)  ·  Peripheral Blood Stem Cell Transplantation (2)  ·  Vorinostat (2)  ·  Whole-Body Irradiation (2)  ·  Bevacizumab (1)  ·  Biopsy (1)  ·  Bortezomib (1)  ·  Cyclophosphamide (1)  ·  Immunologic Techniques (1)  ·  Irinotecan (1)  ·  Isotretinoin (1)  ·  MK 2206 (1)  ·  Oxaliplatin (1)

Sponsors

National Cancer Institute (NCI) (5)  ·  Fred Hutchinson Cancer Center (3)  ·  Morphotek (1)

Countries

United States (9)  ·  Italy (2)  ·  Canada (1)  ·  Germany (1)

Top investigators

Maryam Fouladi (2)  ·  Brenda Sandmaier (1)  ·  Colleen Delaney (1)  ·  David Hong (1)  ·  David Maloney (1)  ·  Jodi Muscal (1)  ·  Lisa McGregor (1)  ·  Robin Norris (1)

Results publications

PMID 32499241, PMID 29292843

NIH funding

U01CA097452 (4), P30CA015704 (2), P01CA018029 (1), P01CA078902 (1), P30CA016672 (1), R24HL074445 (1), R43HL106868 (1), RC2HL101844 (1), U01CA062461 (1)