53 completed, 1 recruiting. 54 Phase 1, 11 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 54 | Completed 53, Recruiting 1 |
| Phase 2 | 11 | Completed 10, Recruiting 1 |
Follow Bird Diseases: new trials by email Literature Review of Bird Diseases trials Research Report on Bird Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Safety and Immunogenicity of the Monovalent Influenza Vaccine A (H5N8) (Inactivated, Fragmented and Adjuvanted) in Adults and Older Adults Monovalent Influenza Vaccine A (H5N8) (Inactivated, Fragmented, and Adjuvanted) 7.5 mcg, Monovalent influenza vaccine type A (H5N8) 15 mcg, Placebo - Avian Influenza A Virus | Phase 1 / Phase 2 | Recruiting | Butantan Institute | 700 | 2025-09-10 | 2026-04-02 |
| A Study to Evaluate the Safety and Immunogenicity of Two Doses of a Novel H5 Central Antigen mRNA-LNP in Healthy Adults H5 AC-Anhui RNA Vaccine, H5 Astrakhan RNA Vaccine, Sodium Chloride, 0.9% - Avian Influenza | Phase 1 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 80 | 2025-06-12 | 2026-06-12 |
| A Study to Find and Confirm the Dose and Assess Safety, Reactogenicity and Immune Response of a Vaccine Against Pandemic H5N1 Influenza Virus in Healthy Younger and Older Adults Flu Pandemic mRNA_Dose level 1, Flu Pandemic mRNA_Dose level 2, Flu Pandemic mRNA_ Dose level 3. - Influenza, Human | Phase 1 / Phase 2 | Completed | GlaxoSmithKline | 991 | 2024-04-18 | 2026-02-05 |
| H5N1 With or Without Topical Aldara in Healthy Adults Aqueous Cream B.P., Imiquimod, Influenza Virus Vaccine, Monovalent A/H5N1 A/Vietnam/1203/04 - Avian Influenza, Influenza Immunisation | Phase 1 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 50 | 2018-06-13 | 2020-02-24 |
| H5N8 Mix and Match With or Without AS03 or MF59 in Healthy Adults: Immunology AS03, MF59, Monovalent Influenza A/H5N8 vaccine - Avian Influenza | Phase 1 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 388 | 2017-01-09 | 2024-09-23 |
| Recombinant H7 Hemagglutinin Influenza Vaccine Trial Recombinant influenza hemagglutinin - Influenza, Avian | Phase 1 | Completed | Vaxine Pty Ltd | 150 | 2017-01-01 | 2019-05-07 |
| H5N8 Mix and Match With or Without AS03 or MF59 in Healthy Adults AS03, MF59 adjuvant, Monovalent Influenza A/H5N8 vaccine - Avian Influenza, Influenza | Phase 1 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 276 | 2016-08-16 | 2019-10-23 |
| A Phase I Study Priming With an Inactivated A/H7N9 Influenza Virus Vaccine With or Without MF59 Adjuvant Followed by Live Attenuated A/H7N9 Influenza Virus Vaccine Influenza Virus Vaccine, Live Attenuated H7N9 Anhui 2013/AA ca, Influenza Virus Vaccine, Monovalent A/H7N9 A/Shanghai/2/2013, MF59 adjuvant - Avian Influenza, Immunisation | Phase 1 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 62 | 2015-05-18 | 2020-01-27 |
| H7 Influenza Prime-Boost Regimens in Healthy Adults: Recombinant H7 DNA Plasmid Vaccine, VRC-FLUDNA071-00-VP, Administered Alone or With Monovalent Influenza Subunit Virion H7N9 Vaccine (MIV) as Prime With MIV Boost Compared to MIV Prime With MIV Boo... A/Shanghai/02/2013 (H7N9) MIV, VRC-FLUDNA071-00-VP - Influenza | Phase 1 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 30 | 2014-07-29 | 2019-12-17 |
| Dose-finding Study of Four Dosage Levels of an H7N9 Influenza Vaccine in Adults Between Ages of 18 Years and 65 Years H7N9c low dose with adjuvant, H7N9c medium dose with adjuvant, H7N9c high dose with adjuvant - H7N9 Influenza | Phase 1 | Completed | Novartis Vaccines | 402 | 2013-08-01 | 2019-06-11 |
| A(H7N9) VLP Antigen Dose Ranging Study With Adjuvant 1 Monovalent Avian Influenza VLP (H7N9), Adjuvant 1, Placebo - Avian Influenza | Phase 1 | Completed | Novavax | 280 | 2013-07-01 | 2014-10-13 |
| Safety and Pharmacokinetics Study of FBF001 FBF001, Placebo - Avian Influenza | Phase 1 | Completed | Fab'entech | 16 | 2012-10-01 | 2014-11-20 |
| Immunogenicity of ND1.1 by Delivery Directly to the Ileum ND1.1 - Avian Influenza | Phase 1 | Completed | Vaxart | 12 | 2012-09-01 | 2014-12-10 |
| A Phase I Study to Evaluate the Safety, Reactogenicity, and Humoral Immune Responses to an Inactivated H5N1 Influenza Vaccine AT-301 - Bird Flu, Avian Influenza | Phase 1 | Completed | Medigen Biotechnology Corporation | 36 | 2012-08-01 | 2013-10-25 |
| H5N1 Vaccination With and Without AS03: Systems Biology Analysis ASO3 Adjuvant, Influenza A/H5N1 Vaccine - Influenza | Phase 1 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 20 | 2012-05-24 | 2019-10-21 |
| Phase I Safety and Immunogenicity of Live Attenuated Influenza H5 Candidate Vaccine Strain A/17/Turkey/Turkey/05/133 (H5N2) in Healthy Thai Volunteers Avian Flu Vaccine, Placebo - Preventive Avian Flu | Phase 1 | Completed | Mahidol University | 2012-05-01 | 2012-08-08 | |
| Safety Trial of Live Attenuated Influenza (H7N3) Vaccine LAIV H7N3, placebo - Influenza, Avian Influenza | Phase 1 | Completed | PATH | 40 | 2012-04-01 | 2019-04-22 |
| H5N1 Mix and Match With MF59 Phosphate Buffered Saline (PBS) diluent, MF59 Adjuvant, H5N1 Antigen - Influenza | Phase 1 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 270 | 2011-05-01 | 2013-01-25 |
| A Follow-On Study With an H5 Influenza Vaccine for Subjects Who Participated in Study FLU-001 INO-3401 + EP - Healthy | Phase 1 | Completed | Inovio Pharmaceuticals | 22 | 2011-05-01 | 2017-09-13 |
| H5N1 Mix and Match With AS03 AS03 Adjuvant, Phosphate Buffered Saline (PBS) diluent, Sanofi H5N1 Antigen - Influenza | Phase 1 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 245 | 2011-05-01 | 2013-01-18 |
Showing 20 of 54. Sign in to see all of them.
Influenza in Birds (53) · Influenza, Human (35) · Virus Diseases (8) · Fowlpox (1) · Orthomyxoviridae Infections (1) · Prostatic Neoplasms (1) · Respiratory Tract Diseases (1)
Animal Diseases (54) · Infections (54) · RNA Virus Infections (53) · Orthomyxoviridae Infections (52) · Virus Diseases (46) · Respiratory Tract Infections (35) · Respiratory Tract Diseases (34) · DNA Virus Infections (1) · Genital Diseases (1) · Genital Diseases, Male (1) · Genital Neoplasms, Male (1) · Male Urogenital Diseases (1) · Neoplasms (1) · Neoplasms by Site (1)
Influenza Vaccines (5) · AS03 adjuvant (2) · Aluminum Hydroxide (2) · Sodium Chloride (2) · Vaccines (2) · Adjuvants, Pharmaceutic (1) · Imiquimod (1) · MF59 oil emulsion (1) · Oseltamivir (1) · Probenecid (1) · SE 1-step Futurabond M (1) · chiron (1) · peramivir (1)
National Institute of Allergy and Infectious Diseases (NIAID) (29) · Alachua Government Services, Inc. (2) · Inovio Pharmaceuticals (2) · Mahidol University (2) · Vaxart (2) · Vical (2) · AVIR Green Hills Biotechnology AG (1) · Altimmune, Inc. (1) · Butantan Institute (1) · Emergent BioSolutions (1) · Fab'entech (1) · GeneOne Life Science, Inc. (1) · GlaxoSmithKline (1) · Green Cross Corporation (1) · Medigen Biotechnology Corporation (1)
United States (40) · Australia (3) · Finland (2) · Russia (2) · South Korea (2) · Thailand (2) · Austria (1) · Belgium (1) · Brazil (1) · Singapore (1) · Spain (1) · Taiwan (1)
Ruth A. Karron, MD (4) · Don Guterwill, BS, MT (2) · D. Nigel Thomas, Ph.D. (1) · David Liebowitz, MD, PhD (1) · Dimitar Sajkov, MD, PhD (1) · Gerald Aichinger, MD (1) · Igor Victorevich (1) · John Treanor, MD (1) · Julie E Ledgerwood, D.O. (1) · Kathleen M Neuzil, MD, MPH (1) · Kawsar Talaat, MD (1) · Larisa G Rudenko, MD, PhD, DSc (1) · Marc Gurwith, M.D., J.D. (1) · Mark Bagarazzi, MD (1)
PMID 19540952, PMID 21975270, PMID 18260764, PMID 18576945, PMID 18808338, PMID 19210163, PMID 19464558, PMID 22542645, PMID 23357198, PMID 23369412, PMID 23633404, PMID 23633407, PMID 24041789, PMID 24224560, PMID 24533064, PMID 25662592, PMID 25734159, PMID 26432909, PMID 28099485, PMID 31155415, PMID 31255574, PMID 33852718, PMID 35115707, PMID 38181048